Ultrafast structural dynamics of photoexcited adenine

2017 ◽  
Vol 19 (30) ◽  
pp. 20224-20240 ◽  
Author(s):  
Sayan Mondal ◽  
Mrinalini Puranik
Keyword(s):  
Electronic Properties ◽  
Excited States ◽  
Structural Dynamics ◽  
Resonance Raman ◽  
Ultraviolet Resonance Raman

Ultraviolet Resonance Raman (UVRR) spectroscopy derives distinct electronic properties of adenine in the La (260 nm) and Bb (210 nm) excited states.

Ultraviolet Resonance Raman Observations of the Structural Dynamics of Rhizobial Oxygen Sensor FixL on Ligand Recognition

2013 ◽  
Vol 117 (49) ◽  
pp. 15786-15791 ◽  
Author(s):  
Shinji Yano ◽  
Haruto Ishikawa ◽  
Misao Mizuno ◽  
Hiro Nakamura ◽  
Yoshitsugu Shiro ◽  
...  
Keyword(s):  
Structural Dynamics ◽  
Oxygen Sensor ◽  
Resonance Raman ◽  
Ligand Recognition ◽  
Ultraviolet Resonance Raman

Initial excited-state structural dynamics of 2′-deoxyadenosine

2019 ◽  
Vol 97 (6) ◽  
pp. 406-412 ◽  
Author(s):  
Swaroop Sasidharanpillai ◽  
Adam A. Friedman ◽  
Glen R. Loppnow
Keyword(s):  
Excited State ◽  
Electronic State ◽  
Structural Dynamics ◽  
Excited Electronic State ◽  
Resonance Raman ◽  
Photochemical Reactions ◽  
Spontaneous Breaking ◽  
Quantum Yields ◽  
Dna And Rna ◽  
Ultraviolet Resonance Raman

Purine nucleobases (adenosine and guanosine) are prone to spontaneous breaking of the nucleosidic bond to form abasic sites in both DNA and RNA. However, the purines also undergo photochemical reactions, including oxidation and cycloaddition, to form damage sites, albeit at lower photochemical quantum yields than the pyrimidines. In this study, we use ultraviolet resonance Raman spectroscopy to measure the initial excited-state structural dynamics in the nucleoside, 2′-deoxyadenosine. The resonance Raman-derived initial excited-state structural dynamics throughout the 260 nm La excited electronic state of adenine are found to be smaller in the nucleoside than in the previously reported 9-methyladenine nucleobase derivative, consistent with what is found for the pyrimidines thymine and uracil. Interestingly, resonance-enhanced vibrational modes in this electronic state also contain internal coordinates localized on the sugar, which may represent a different energy dissipation mechanism than in the pyrimidine nucleosides. The results will be discussed in terms of the initial excited-state photophysics and photochemistry of DNA and RNA.

Sign in / Sign up

Export Citation Format

Share Document