scholarly journals Hierarchical supramolecular hydrogels: self-assembly by peptides and photo-controlled release via host–guest interaction

2017 ◽  
Vol 53 (92) ◽  
pp. 12450-12453 ◽  
Author(s):  
Chih-Wei Chu ◽  
Bart Jan Ravoo
Keyword(s):  
Controlled Release ◽  
Self Assembly ◽  
Peptide Hydrogel ◽  
Guest Chemistry

Using photoresponsive host–guest chemistry, three different payloads can be photo-released successively from the same peptide hydrogel.

A water-soluble pillar[6]arene: synthesis, host–guest chemistry, controllable self-assembly, and application in controlled release

RSC Advances ◽  
2014 ◽  
Vol 4 (18) ◽  
pp. 9039 ◽  
Author(s):  
Yong Yao ◽  
Jinying Li ◽  
Jing Dai ◽  
Xiaodong Chi ◽  
Min Xue
Keyword(s):  
Controlled Release ◽  
Self Assembly ◽  
Water Soluble ◽  
Guest Chemistry

scholarly journals Nanostructure, Self-Assembly, Mechanical Properties, and Antioxidant Activity of a Lupin-Derived Peptide Hydrogel

Biomedicines ◽  
2021 ◽  
Vol 9 (3) ◽  
pp. 294
Author(s):  
Raffaele Pugliese ◽  
Anna Arnoldi ◽  
Carmen Lammi
Keyword(s):  
Mechanical Properties ◽  
Antioxidant Activity ◽  
Self Assembly ◽  
Antioxidant Activities ◽  
Functional Materials ◽  
Cd Spectroscopy ◽  
Beneficial Effects ◽  
Naturally Occurring ◽  
New Research ◽  
Peptide Hydrogel

Naturally occurring food peptides are frequently used in the life sciences due to their beneficial effects through their impact on specific biochemical pathways. Furthermore, they are often leveraged for applications in areas as diverse as bioengineering, medicine, agriculture, and even fashion. However, progress toward understanding their self-assembling properties as functional materials are often hindered by their long aromatic and charged residue-enriched sequences encrypted in the parent protein sequence. In this study, we elucidate the nanostructure and the hierarchical self-assembly propensity of a lupin-derived peptide which belongs to the α-conglutin (11S globulin, legumin-like protein), with a straightforward N-terminal biotinylated oligoglycine tag-based methodology for controlling the nanostructures, biomechanics, and biological features. Extensive characterization was performed via Circular Dichroism (CD) spectroscopy, Fourier Transform Infrared spectroscopy (FT-IR), rheological measurements, and Atomic Force Microscopy (AFM) analyses. By using the biotin tag, we obtained a thixotropic lupin-derived peptide hydrogel (named BT13) with tunable mechanical properties (from 2 to 11 kPa), without impairing its spontaneous formation of β-sheet secondary structures. Lastly, we demonstrated that this hydrogel has antioxidant activity. Altogether, our findings address multiple challenges associated with the development of naturally occurring food peptide-based hydrogels, offering a new tool to both fine tune the mechanical properties and tailor the antioxidant activities, providing new research directions across food chemistry, biochemistry, and bioengineering.

Multilayer composite beads constructed via layer-by-layer self-assembly for lysozyme controlled release

RSC Advances ◽  
2014 ◽  
Vol 4 (46) ◽  
pp. 24369-24376 ◽  
Author(s):  
Jiemin Zhao ◽  
Xiaoping Wang ◽  
Yanshen Kuang ◽  
Yufeng Zhang ◽  
Xiaowen Shi ◽  
...  
Keyword(s):  
Controlled Release ◽  
Self Assembly ◽  
Cross Linking ◽  
Layer By Layer ◽  
Multilayer Composite ◽  
Composite Beads ◽  
Assembly Technique ◽  
Positively Charged

Alginate (ALG)–lysozyme (LZ) beads were fabricated by a cross-linking process. Negatively charged ALG and positively charged LZ were alternately deposited on the positively charged ALG–LZ beads via a layer-by-layer (LBL) self-assembly technique.

Microcapsules for controlled release fabricated via layer-by-layer self-assembly of polyelectrolytes

2008 ◽  
Vol 3 (2) ◽  
pp. 133-145 ◽  
Author(s):  
Chaoyang Wang ◽  
Shiqu Ye ◽  
Qilong Sun ◽  
Chengyi He ◽  
Weihua Ye ◽  
...  
Keyword(s):  
Controlled Release ◽  
Self Assembly ◽  
Layer By Layer

Continuous Microfluidic Self-Assembly of Hybrid Janus-Like Vesicular Motors: Autonomous Propulsion and Controlled Release

Small ◽  
2015 ◽  
Vol 11 (31) ◽  
pp. 3762-3767 ◽  
Author(s):  
Lei Wang ◽  
Yijing Liu ◽  
Jie He ◽  
Matthew J. Hourwitz ◽  
Yunlong Yang ◽  
...  
Keyword(s):  
Controlled Release ◽  
Self Assembly

Enhanced Entrapment and Improved in Vitro Controlled Release of N-Acetyl Cysteine in Hybrid PLGA/Lecithin Nanoparticles Prepared Using a Nanoprecipitation/Self-Assembly Method

2017 ◽  
Vol 118 (12) ◽  
pp. 4203-4209 ◽  
Author(s):  
Parvin Ahmaditabar ◽  
Amir A. Momtazi-Borojeni ◽  
Ali H. Rezayan ◽  
Mahboobeh Mahmoodi ◽  
Amirhossein Sahebkar ◽  
...  
Keyword(s):  
Controlled Release ◽  
Self Assembly ◽  
Assembly Method ◽  
Acetyl Cysteine

From hollow lignin microsphere preparation to simultaneous preparation of urea encapsulation for controlled release using industrial kraft lignin via slow and exhaustive acetone-water evaporation

Holzforschung ◽  
2019 ◽  
Vol 74 (1) ◽  
pp. 77-87 ◽  
Author(s):  
Miao Wang ◽  
Yadong Zhao ◽  
Jiebing Li
Keyword(s):  
Controlled Release ◽  
Self Assembly ◽  
Average Diameter ◽  
Kraft Lignin ◽  
Water Evaporation ◽  
Shell Wall ◽  
Straightforward Method ◽  
Acetone Water ◽  
Direct Preparation ◽  
Microsphere Preparation

AbstractLignin nano/microparticles have recently attracted growing interest for various value-additive applications of lignin, especially encapsulation. In this study, in order to establish a highly efficient and highly productive preparation process to effectively utilize technical lignin, a brand-new, slow and exhaustive solution evaporation process following a simple, self-assembly principle was developed using industrial softwood kraft lignin (SKL) from a starting acetone-water (80/20, v/v) solution to recover 100% of the lignin as homogeneous and well-shaped microspheres. The prepared microspheres had a typical average diameter of 0.81 ± 0.15 μm and were hollow with very thin shells (of nanoscale thickness). Based on this developed technique, encapsulation of urea by these lignin microspheres was directly achieved using the same process as hollow lignin microspheres with urea attached to the outside and entrapped inside of the wall. Two distinct urea release rates were observed for the urea-encapsulated microspheres: a fast release of the urea outside the shell wall and a slow (controlled) release of the urea inside the shell wall. The encapsulation efficiency was as high as 46% of the trapped urea as encapsulated inside the lignin microspheres. The slow and exhaustive solution evaporation procedure reported here is a simple and straightforward method for the valorization of industrial kraft lignin as hollow microspheres with controllable, homogeneous and desired morphologies, and especially for the direct preparation of lignin-based encapsulating fertilizers for controlled release.

scholarly journals ATRP-based synthesis of a pH-sensitive amphiphilic block polymer and its self-assembled micelles with hollow mesoporous silica as DOX carriers for controlled drug release

RSC Advances ◽  
2021 ◽  
Vol 11 (48) ◽  
pp. 29986-29996
Author(s):  
Xiuxiu Qi ◽  
Hongmei Yan ◽  
Yingxue Li
Keyword(s):  
Controlled Release ◽  
Drug Release ◽  
Self Assembly ◽  
Drug Loading ◽  
Controlled Drug Release ◽  
Ph Sensitive ◽  
Core Shell ◽  
Assembly Process ◽  
Block Polymer ◽  
Hollow Mesoporous Silica

A pH-sensitive core–shell nanoparticle (HMS@C18@PSDMA-b-POEGMA) was developed via a self-assembly process as the carrier of anticancer drug doxorubicin (DOX) for drug loading and controlled release.

A water-soluble biphen[3]arene: synthesis, host–guest complexation, and application in controllable self-assembly and controlled release

2015 ◽  
Vol 51 (20) ◽  
pp. 4188-4191 ◽  
Author(s):  
Jiong Zhou ◽  
Guocan Yu ◽  
Li Shao ◽  
Bin Hua ◽  
Feihe Huang
Keyword(s):  
Controlled Release ◽  
Self Assembly ◽  
Water Soluble ◽  
Ammonium Salts ◽  
Ph Responsive ◽  
Recognition Motif

The first water-soluble biphen[3]arene was synthesized. Its pH-responsive host–guest complexation with secondary ammonium salts in water was investigated. This novel recognition motif was further used in controllable self-assembly and controlled release.

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