Synthetic route to chiral indolines via Cu(OAc)2-catalyzed ring-opening/C(sp2)–H activation of activated aziridines

2017 ◽  
Vol 53 (74) ◽  
pp. 10263-10266 ◽  
Author(s):  
Abhijit Mal ◽  
Gaurav Goswami ◽  
Imtiyaz Ahmad Wani ◽  
Manas K. Ghorai
Keyword(s):  
Lewis Acid ◽  
Ring Opening ◽  
Synthetic Route ◽  
One Pot ◽  
Acid Catalyzed

A novel synthetic route to functionalized indolinesviaLewis acid catalyzed ring-opening of activated aziridines followed by Cu(OAc)2-mediated intramolecular C–H amination in one-pot with excellent enantio- and diastereospecificity (ee 99%; de >99%).

Stereoselective synthesis of 3-spiropiperidino indoleninesviaSN2-type ring opening of activated aziridines with 1H-indoles/Pd-catalyzed spirocyclization with propargyl carbonates

2018 ◽  
Vol 54 (62) ◽  
pp. 8583-8586 ◽  
Author(s):  
Sajan Pradhan ◽  
Chandan Kumar Shahi ◽  
Aditya Bhattacharyya ◽  
Manas K. Ghorai
Keyword(s):  
Lewis Acid ◽  
Ring Opening ◽  
Stereoselective Synthesis ◽  
Synthetic Route ◽  
Acid Catalyzed ◽  
High Yields

A novel synthetic route to 3-spiropiperidino indoleninesviaLewis acid catalyzed SN2-type ring opening of activated aziridines with 1H-indoles followed by Pd-catalyzed spirocyclization with propargyl carbonates in high yields (up to 88%) with excellent diastereo- and enantiospecificity (dr >99 : 1; ee up to >99) is reported.

A heavy metal- and oxidant-free, one-pot synthesis of pyridines and fused pyridines based on a Lewis acid-catalyzed multicomponent reaction

2014 ◽  
Vol 50 (82) ◽  
pp. 12270-12272 ◽  
Author(s):  
V. P. Alex Raja ◽  
Giammarco Tenti ◽  
Subbu Perumal ◽  
J. Carlos Menéndez
Keyword(s):  
Heavy Metal ◽  
Lewis Acid ◽  
Multicomponent Reaction ◽  
One Pot ◽  
One Pot Synthesis ◽  
Acid Catalyzed

Pyridines and fused pyridines are accessible by a combination of a Lewis acid-catalyzed multicomponent reaction and aromatization involving loss of a 2-furylmethyl chain.

Lewis acid-catalyzed tandem cyclization of in situ generated o-quinone methides and arylsulfonyl hydrazides for a one-pot entry to 3-sulfonylbenzofurans

2019 ◽  
Vol 6 (24) ◽  
pp. 3929-3933 ◽  
Author(s):  
Fan-Xiao Meng ◽  
Ruo-Nan Wang ◽  
Hong-Li Huang ◽  
Shu-Wen Gong ◽  
Qian-Li Li ◽  
...  
Keyword(s):  
Lewis Acid ◽  
Quinone Methides ◽  
One Pot ◽  
Acid Catalyzed ◽  
Tandem Cyclization ◽  
First Time

Lewis acid-mediated one-pot tandem cyclization of o-QMs with arylsulfonyl hydrazides was described for the first time and the corresponding 3-sulfonylbenzofuran products were obtained in moderate to good yields.

scholarly journals Lewis Acid Catalyzed Ring-Opening 1,3-Aminothiolation of Donor–Acceptor Cyclopropanes Using Sulfenamides

2020 ◽  
Vol 22 (6) ◽  
pp. 2276-2280 ◽  
Author(s):  
Avishek Guin ◽  
Thukaram Rathod ◽  
Rahul N. Gaykar ◽  
Tony Roy ◽  
Akkattu T. Biju
Keyword(s):  
Lewis Acid ◽  
Ring Opening ◽  
Donor Acceptor ◽  
Acid Catalyzed
Sign in / Sign up

Export Citation Format

Share Document