pH-Sensitive metal-free carbon monoxide prodrugs with tunable and predictable release rates

2017 ◽  
Vol 53 (69) ◽  
pp. 9628-9631 ◽  
Author(s):  
Xingyue Ji ◽  
Ladie Kimberly C. De La Cruz ◽  
Zhixiang Pan ◽  
Vayou Chittavong ◽  
Binghe Wang
Keyword(s):  
Carbon Monoxide ◽  
Side Effects ◽  
Ph Sensitive ◽  
Free Carbon ◽  
Release Rates ◽  
Triggered Release ◽  
Metal Free ◽  
Release Profiles

Carbon monoxide prodrugs with triggered release profiles are highly desirable for targeted CO delivery to minimize their untoward side-effects.

scholarly journals Metal-free carbon monoxide-releasing micelles undergo tandem photochemical reactions for cutaneous wound healing

2020 ◽  
Vol 11 (17) ◽  
pp. 4499-4507 ◽  
Author(s):  
Jian Cheng ◽  
Bin Zheng ◽  
Sheng Cheng ◽  
Guoying Zhang ◽  
Jinming Hu
Keyword(s):  
Carbon Monoxide ◽  
Wound Healing ◽  
Photochemical Reactions ◽  
Free Carbon ◽  
Cutaneous Wound Healing ◽  
Cutaneous Wound ◽  
Metal Free ◽  
Improved Stability

Metal-free carbon monoxide-releasing polymers (CORPs) are synthesized via a direct polymerization approach, exhibiting not only improved stability but also accelerated wound healing performance as compared to CORM-3.

scholarly journals Front Cover Picture: Metal‐free Carbon Monoxide (CO) Capture and Utilization: Formylation of Amines (Adv. Synth. Catal. 13/2019)

2019 ◽  
Vol 361 (13) ◽  
pp. 3015-3015
Author(s):  
Hyeong‐Wan Noh ◽  
Youngjoon An ◽  
Seulchan Lee ◽  
Jaehoon Jung ◽  
Seung Uk Son ◽  
...  
Keyword(s):  
Carbon Monoxide ◽  
Free Carbon ◽  
Front Cover ◽  
Metal Free

Metal‐free Carbon Monoxide (CO) Capture and Utilization: Formylation of Amines

2019 ◽  
Vol 361 (13) ◽  
pp. 3068-3073 ◽  
Author(s):  
Hyeong‐Wan Noh ◽  
Youngjoon An ◽  
Seulchan Lee ◽  
Jaehoon Jung ◽  
Seung Uk Son ◽  
...  
Keyword(s):  
Carbon Monoxide ◽  
Free Carbon ◽  
Metal Free

Xanthene-9-carboxylic acid: A photo-activatable transition-metal-free carbon monoxide-releasing molecule with extraordinary long half-life

Nitric Oxide ◽  
2015 ◽  
Vol 47 ◽  
pp. S35 ◽  
Author(s):  
Lucie Muchová ◽  
Jana Jašprová ◽  
Tomáš Slanina ◽  
Peter Šebej ◽  
Petr Klán ◽  
...  
Keyword(s):  
Carbon Monoxide ◽  
Carboxylic Acid ◽  
Transition Metal ◽  
Half Life ◽  
Free Carbon ◽  
Metal Free

Transition-metal-free carbonylation of aryl halides with arylboronic acids by utilizing stoichiometric CHCl3 as the carbon monoxide-precursor

2019 ◽  
Vol 21 (11) ◽  
pp. 2911-2915 ◽  
Author(s):  
Fangning Xu ◽  
Dan Li ◽  
Wei Han
Keyword(s):  
Carbon Monoxide ◽  
Transition Metal ◽  
Suzuki Coupling ◽  
Free Carbon ◽  
Aryl Halides ◽  
Metal Free ◽  
Arylboronic Acids ◽  
General Methodology

A transition-metal-free, carbon monoxide-free, and general methodology for carbonylative Suzuki coupling has been developed.

scholarly journals Dissolution Testing of Nicotine Release from OTDN Pouches: Product Characterization and Product-to-Product Comparison

Separations ◽  
2021 ◽  
Vol 8 (1) ◽  
pp. 7
Author(s):  
Fadi Aldeek ◽  
Nicholas McCutcheon ◽  
Cameron Smith ◽  
John H. Miller ◽  
Timothy L. Danielson
Keyword(s):  
In Vitro Release ◽  
Product Category ◽  
Immediate Release ◽  
Tobacco Product ◽  
Oral Dosage ◽  
Dissolution Testing ◽  
Release Rates ◽  
Usp 4 ◽  
Release Profiles

In recent years, oral tobacco-derived nicotine (OTDN) pouches have emerged as a new oral tobacco product category. They are available in a variety of flavors and do not contain cut or ground tobacco leaf. The on!® nicotine pouches fall within this category of OTDN products and are currently marketed in seven (7) flavors with five (5) different nicotine levels. Evaluation of the nicotine release from these products is valuable for product assessment and product-to-product comparisons. In this work, we characterized the in vitro release profiles of nicotine from the 35 varieties of on!® nicotine pouches using a fit-for-purpose dissolution method, employing the U.S. Pharmacopeia flow-through cell dissolution apparatus 4 (USP-4). The nicotine release profiles were compared using the FDA’s Guidance for Industry: Dissolution Testing of Immediate Release Solid Oral Dosage Forms. The cumulative release profiles of nicotine show a dose dependent response for all nicotine levels. The on!® nicotine pouches exhibit equivalent percent nicotine release rates for each flavor variant across all nicotine levels. Furthermore, the nicotine release profiles from on!® nicotine pouches were compared to a variety of other commercially available OTDN pouches and traditional pouched smokeless tobacco products. The percent nicotine release rates were found to be dependent on the product characteristics, showing similarities and differences in the nicotine release profiles between the on!® nicotine pouches and other compared products.

Hydrogen Peroxide Generation with 100% Faradaic Efficiency on Metal-Free Carbon Black

ACS Catalysis ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 2454-2459
Author(s):  
Zhe Wang ◽  
Qin-Kun Li ◽  
Chenhao Zhang ◽  
Zhihua Cheng ◽  
Weiyin Chen ◽  
...  
Keyword(s):  
Hydrogen Peroxide ◽  
Carbon Black ◽  
Free Carbon ◽  
Faradaic Efficiency ◽  
Metal Free ◽  
Hydrogen Peroxide Generation

Potassium hydroxide as a novel catalyst for metal-free carbon nanotubes growth on powder activated carbon

2021 ◽  
pp. 413294
Author(s):  
Belal Abu Tarboush ◽  
Farouq S. Mjalli ◽  
Mohammed Abdulhakim Alsaadi ◽  
Mustafa Mohammed Aljumaily
Keyword(s):  
Carbon Nanotubes ◽  
Activated Carbon ◽  
Potassium Hydroxide ◽  
Free Carbon ◽  
Metal Free ◽  
Powder Activated Carbon ◽  
Novel Catalyst

Unique Layer‐Doping‐Induced Regulation of Charge Behavior in Metal‐Free Carbon Nitride Photoanodes for Enhanced Performance

ChemSusChem ◽  
2019 ◽  
Vol 13 (2) ◽  
pp. 328-333 ◽  
Author(s):  
Peng Luan ◽  
Qingqiang Meng ◽  
Jing Wu ◽  
Qinye Li ◽  
Xiaolong Zhang ◽  
...  
Keyword(s):  
Carbon Nitride ◽  
Free Carbon ◽  
Metal Free
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