Synthesis of enaminones via copper-catalyzed decarboxylative coupling reaction under redox-neutral conditions

2017 ◽  
Vol 53 (22) ◽  
pp. 3228-3231 ◽  
Author(s):  
Zhongzhi Zhu ◽  
Xiaodong Tang ◽  
Jianxiao Li ◽  
Xianwei Li ◽  
Wanqing Wu ◽  
...  
Keyword(s):  
Coupling Reaction ◽  
Oxidative Functionalization ◽  
Decarboxylative Coupling ◽  
Neutral Conditions

A novel copper-catalyzed C(sp3)–H oxidative functionalization of oxime acetates for the synthesis of enaminones under redox-neutral conditions has been developed.

Ni(0)-Catalyzed α-Allylic Alkylation of Regular Ketones with 1,3-Dienes under pH and Redox-neutral Conditions

2019 ◽  
Author(s):  
Tiantian Chen ◽  
Yang Yang ◽  
Liyu Xie ◽  
Haijian Yang ◽  
Guangbin Dong ◽  
...  
Keyword(s):  
Oxidative Addition ◽  
Coupling Reaction ◽  
Cross Coupling ◽  
Dual Role ◽  
Allylic Alkylation ◽  
Cross Coupling Reaction ◽  
Neutral Conditions

<p>We report a Ni(0)-catalyzed cross coupling reaction between simple ketones and 1,3-dienes. A variety of a-allylic alkylation products were formed in an 1,2-addition manner with excellent regioselectivity. Water was found to significantly accelerate this transformation. A HO-Ni-H species generated from oxidative addition of Ni(0) to H<sub>2</sub>O is proposed to play a “dual role” in activating both the ketone and the diene substrate.</p>

Palladium-catalyzed decarboxylative coupling reaction with alkynyl carboxylic acids and arylsiloxanes

2016 ◽  
Vol 57 (41) ◽  
pp. 4581-4584 ◽  
Author(s):  
Jisun Jang ◽  
Gabriel Charles Edwin Raja ◽  
Ju-Hyeon Lee ◽  
Yujeong Son ◽  
Jimin Kim ◽  
...  
Keyword(s):  
Carboxylic Acids ◽  
Coupling Reaction ◽  
Decarboxylative Coupling ◽  
Palladium Catalyzed

Electrochemical synthesis of enaminones via a decarboxylative coupling reaction

2019 ◽  
Vol 21 (14) ◽  
pp. 3796-3801 ◽  
Author(s):  
Xianqiang Kong ◽  
Yulong Liu ◽  
Long Lin ◽  
Qianjin Chen ◽  
Bo Xu
Keyword(s):  
Electrochemical Synthesis ◽  
Coupling Reaction ◽  
Metal Free ◽  
Redox Catalyst ◽  
Decarboxylative Coupling

Metal-free and oxidant-free n-Bu4NI as a redox catalyst and electrolyte.

An unprecedented Pd-catalyzed decarboxylative coupling reaction of aromatic carboxylic acids in aqueous medium under air: synthesis of 3-aryl-imidazo[1,2-a]pyridines from aryl chlorides

2016 ◽  
Vol 14 (1) ◽  
pp. 246-250 ◽  
Author(s):  
Bing Mu ◽  
Yusheng Wu ◽  
Jingya Li ◽  
Dapeng Zou ◽  
Junbiao Chang ◽  
...  
Keyword(s):  
Aqueous Medium ◽  
Carboxylic Acids ◽  
Coupling Reaction ◽  
Aromatic Carboxylic Acids ◽  
Aryl Chlorides ◽  
Decarboxylative Coupling ◽  
Palladium Catalyzed

An efficient and facile protocol for the synthesis of 3-aryl-imidazo[1,2-a]pyridines was investigated via palladium-catalyzed decarboxylative arylation of imidazo[1,2-a]pyridine-3-carboxylic acids.

scholarly journals Mechanistic studies on the metal-free decarboxylative coupling reaction for synthesis of propargylamines by NMR

ARKIVOC ◽  
2016 ◽  
Vol 2016 (5) ◽  
pp. 1-12
Author(s):  
Yongjun Lee ◽  
Kyungho Park ◽  
Han-Sung Kim ◽  
Jimin Kim ◽  
Young Ju Lee ◽  
...  
Keyword(s):  
Coupling Reaction ◽  
Mechanistic Studies ◽  
Metal Free ◽  
Decarboxylative Coupling
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