Three-dimensional multiscale fiber matrices: development and characterization for increased HepG2 functional maintenance for bio-artificial liver application

2018 ◽  
Vol 6 (2) ◽  
pp. 280-291 ◽  
Author(s):  
Surendra Kumar Verma ◽  
Akshay Modi ◽  
Jayesh Bellare
Keyword(s):  
Hepg2 Cells ◽  
Three Dimensional ◽  
Characteristic Functions ◽  
Artificial Liver ◽  
Fiber Matrices ◽  
One Step

One-step development of three-dimensional multiscale fiber matrices to enhance attachment, proliferation, and characteristic functions of HepG2 cells.

Three-dimensional high-density culture of HepG2 cells in a 5-ml radial-flow bioreactor for construction of artificial liver

2005 ◽  
Vol 99 (3) ◽  
pp. 237-244 ◽  
Author(s):  
Tomokatsu Hongo ◽  
Mariko Kajikawa ◽  
Seiichi Ishida ◽  
Shogo Ozawa ◽  
Yasuo Ohno ◽  
...  
Keyword(s):  
Hepg2 Cells ◽  
Radial Flow ◽  
Three Dimensional ◽  
High Density ◽  
Artificial Liver ◽  
High Density Culture ◽  
Radial Flow Bioreactor

Controllable Electrochemical Synthesis of Ag Hierarchical Micro/Nanostructures with High SERS-Activity

NANO ◽  
2020 ◽  
Vol 15 (04) ◽  
pp. 2050043
Author(s):  
Huayu Zhou ◽  
Jingjing Wang ◽  
Qiong Yang ◽  
Menglei Chen ◽  
Changsheng Song ◽  
...  
Keyword(s):  
Indium Tin Oxide ◽  
Current System ◽  
Three Dimensional ◽  
Constant Current ◽  
Localized Surface Plasmon ◽  
Excitation Wavelength ◽  
Raman Signal ◽  
Mixed Solution ◽  
Raman Enhancement ◽  
One Step

We report a one-step electrochemical deposition technique to prepare three-dimensional (3D) Ag hierarchical micro/nanostructured film consisting of well-crystallized Ag nanosheets grown on an indium tin oxide (ITO) conductive substrate. The Ag hierarchical micro/nanostructures were fabricated in the mixed solution of AgNO3 and sodium citrate in a constant current system at room temperature. Through reduction of Ag[Formula: see text] electrodeposited on the surface of ITO substrate, nanoparticles were grown to form nanosheets which further combined into 3D sphere-like microstructures. The 3D Ag micro/nanostructures have many sharp edges and nanoscale gaps which can give rise to good Raman-enhanced effect. Due to localized surface plasmon resonance (LSPR) effects, these special Ag micro/nanostructures exhibited good Raman-enhanced performance. Using Rhodamine 6G (R6G) molecules as probe molecule, we studied the influence of excitation wavelength on Raman enhancement. The results showed that the 532[Formula: see text]nm excitation wavelength is the best to obtain the strongest Raman signal and to reduce the influence of other impurity peaks. Using the as-synthesized Ag hierarchical micro/nanostructures, we can detect the 10[Formula: see text][Formula: see text]mol/L R6G aqueous solution, exhibiting great Raman-enhanced effect.

scholarly journals A Review on Additive Manufacturing Possibilities for Electrical Machines

Energies ◽  
2021 ◽  
Vol 14 (7) ◽  
pp. 1940
Author(s):  
Muhammad Usman Naseer ◽  
Ants Kallaste ◽  
Bilal Asad ◽  
Toomas Vaimann ◽  
Anton Rassõlkin
Keyword(s):  
Additive Manufacturing ◽  
Large Scale ◽  
Three Dimensional ◽  
Electrical Machines ◽  
Electromagnetic Properties ◽  
Scale Production ◽  
Performance Parameters ◽  
Large Scale Production ◽  
One Step ◽  
Manufacturing Techniques

This paper presents current research trends and prospects of utilizing additive manufacturing (AM) techniques to manufacture electrical machines. Modern-day machine applications require extraordinary performance parameters such as high power-density, integrated functionalities, improved thermal, mechanical & electromagnetic properties. AM offers a higher degree of design flexibility to achieve these performance parameters, which is impossible to realize through conventional manufacturing techniques. AM has a lot to offer in every aspect of machine fabrication, such that from size/weight reduction to the realization of complex geometric designs. However, some practical limitations of existing AM techniques restrict their utilization in large scale production industry. The introduction of three-dimensional asymmetry in machine design is an aspect that can be exploited most with the prevalent level of research in AM. In order to take one step further towards the enablement of large-scale production of AM-built electrical machines, this paper also discusses some machine types which can best utilize existing developments in the field of AM.

scholarly journals Is Dialdehyde Chitosan a Good Substance to Modify Physicochemical Properties of Biopolymeric Materials?

2021 ◽  
Vol 22 (7) ◽  
pp. 3391
Author(s):  
Sylwia Grabska-Zielińska ◽  
Alina Sionkowska ◽  
Ewa Olewnik-Kruszkowska ◽  
Katarzyna Reczyńska ◽  
Elżbieta Pamuła
Keyword(s):  
Mechanical Properties ◽  
Tissue Engineering ◽  
Physicochemical Properties ◽  
Silk Fibroin ◽  
Three Dimensional ◽  
Microscopy Imaging ◽  
Maximum Deformation ◽  
One Step ◽  
Chitosan Blends ◽  
Fourier Transfer Infrared Spectroscopy

The aim of this work was to compare physicochemical properties of three dimensional scaffolds based on silk fibroin, collagen and chitosan blends, cross-linked with dialdehyde starch (DAS) and dialdehyde chitosan (DAC). DAS was commercially available, while DAC was obtained by one-step synthesis. Structure and physicochemical properties of the materials were characterized using Fourier transfer infrared spectroscopy with attenuated total reflectance device (FTIR-ATR), swelling behavior and water content measurements, porosity and density observations, scanning electron microscopy imaging (SEM), mechanical properties evaluation and thermogravimetric analysis. Metabolic activity with AlamarBlue assay and live/dead fluorescence staining were performed to evaluate the cytocompatibility of the obtained materials with MG-63 osteoblast-like cells. The results showed that the properties of the scaffolds based on silk fibroin, collagen and chitosan can be modified by chemical cross-linking with DAS and DAC. It was found that DAS and DAC have different influence on the properties of biopolymeric scaffolds. Materials cross-linked with DAS were characterized by higher swelling ability (~4000% for DAS cross-linked materials; ~2500% for DAC cross-linked materials), they had lower density (Coll/CTS/30SF scaffold cross-linked with DAS: 21.8 ± 2.4 g/cm3; cross-linked with DAC: 14.6 ± 0.7 g/cm3) and lower mechanical properties (maximum deformation for DAC cross-linked scaffolds was about 69%; for DAS cross-linked scaffolds it was in the range of 12.67 ± 1.51% and 19.83 ± 1.30%) in comparison to materials cross-linked with DAC. Additionally, scaffolds cross-linked with DAS exhibited higher biocompatibility than those cross-linked with DAC. However, the obtained results showed that both types of scaffolds can provide the support required in regenerative medicine and tissue engineering. The scaffolds presented in the present work can be potentially used in bone tissue engineering to facilitate healing of small bone defects.

scholarly journals Novel hybrid three-dimensional artificial liver using human induced pluripotent stem cells and a rat decellularized liver scaffold

2019 ◽  
Vol 10 ◽  
pp. 127-133 ◽  
Author(s):  
Takahito Minami ◽  
Takamichi Ishii ◽  
Kentaro Yasuchika ◽  
Ken Fukumitsu ◽  
Satoshi Ogiso ◽  
...  
Keyword(s):  
Stem Cells ◽  
Induced Pluripotent Stem Cells ◽  
Pluripotent Stem Cells ◽  
Three Dimensional ◽  
Artificial Liver ◽  
Induced Pluripotent ◽  
Decellularized Liver

Three-dimensional graphene/polyimide composite-derived flexible high-performance organic cathode for rechargeable lithium and sodium batteries

2017 ◽  
Vol 5 (6) ◽  
pp. 2710-2716 ◽  
Author(s):  
Yanshan Huang ◽  
Ke Li ◽  
Jingjing Liu ◽  
Xing Zhong ◽  
Xiangfeng Duan ◽  
...  
Keyword(s):  
High Performance ◽  
Three Dimensional ◽  
3D Graphene ◽  
Sodium Batteries ◽  
One Step

A 3D graphene/polyimide composite is fabricated by a one-step solvothermal strategy as a high-performance cathode for both rechargeable lithium and sodium batteries.

Three-dimensional graphene oxide/polypyrrole composite electrodes fabricated by one-step electrodeposition for high performance supercapacitors

2015 ◽  
Vol 3 (27) ◽  
pp. 14445-14457 ◽  
Author(s):  
Jianyun Cao ◽  
Yaming Wang ◽  
Junchen Chen ◽  
Xiaohong Li ◽  
Frank C. Walsh ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
High Performance ◽  
Three Dimensional ◽  
Composite Electrodes ◽  
Ion Diffusion ◽  
One Step ◽  
Supercapacitor Performance ◽  
Polypyrrole Composite ◽  
Fast Ion ◽  
Interconnected Structure

The 3D interconnected structure of the GO/PPy composite ensures fast ion diffusion through the electrode, leading to excellent supercapacitor performance.

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