Bilayered nanofibrous 3D hierarchy as skin rudiment by emulsion electrospinning for burn wound management

2017 ◽  
Vol 5 (9) ◽  
pp. 1786-1799 ◽  
Author(s):  
Pallabi Pal ◽  
Prabhash Dadhich ◽  
Pavan Kumar Srivas ◽  
Bodhisatwa Das ◽  
Dhrubajyoti Maulik ◽  
...  
Keyword(s):  
Extracellular Matrix ◽  
Skin Graft ◽  
Wound Management ◽  
Cotton Wool ◽  
Burn Wound ◽  
Membranous Structure ◽  
Matrix Hierarchy

Mimicking skin extracellular matrix hierarchy, the present work aims to develop a bilayer skin graft comprising a porous cotton-wool-like 3D layer with membranous structure of PCL–chitosan nanofibers.

scholarly journals A Narrative Review of the History of Skin Grafting in Burn Care

Medicina ◽  
2021 ◽  
Vol 57 (4) ◽  
pp. 380
Author(s):  
Deepak K. Ozhathil ◽  
Michael W. Tay ◽  
Steven E. Wolf ◽  
Ludwik K. Branski
Keyword(s):  
Donor Site ◽  
Subsequent Development ◽  
Skin Grafting ◽  
Human Condition ◽  
Surgical Instruments ◽  
Wound Management ◽  
Burn Wound ◽  
Medical Progress ◽  
Burn Care ◽  
History Of

Thermal injuries have been a phenomenon intertwined with the human condition since the dawn of our species. Autologous skin translocation, also known as skin grafting, has played an important role in burn wound management and has a rich history of its own. In fact, some of the oldest known medical texts describe ancient methods of skin translocation. In this article, we examine how skin grafting has evolved from its origins of necessity in the ancient world to the well-calibrated tool utilized in modern medicine. The popularity of skin grafting has ebbed and flowed multiple times throughout history, often suppressed for cultural, religious, pseudo-scientific, or anecdotal reasons. It was not until the 1800s, that skin grafting was widely accepted as a safe and effective treatment for wound management, and shortly thereafter for burn injuries. In the nineteenth and twentieth centuries skin grafting advanced considerably, accelerated by exponential medical progress and the occurrence of man-made disasters and global warfare. The introduction of surgical instruments specifically designed for skin grafting gave surgeons more control over the depth and consistency of harvested tissues, vastly improving outcomes. The invention of powered surgical instruments, such as the electric dermatome, reduced technical barriers for many surgeons, allowing the practice of skin grafting to be extended ubiquitously from a small group of technically gifted reconstructive surgeons to nearly all interested sub-specialists. The subsequent development of biologic and synthetic skin substitutes have been spurred onward by the clinical challenges unique to burn care: recurrent graft failure, microbial wound colonization, and limited donor site availability. These improvements have laid the framework for more advanced forms of tissue engineering including micrografts, cultured skin grafts, aerosolized skin cell application, and stem-cell impregnated dermal matrices. In this article, we will explore the convoluted journey that modern skin grafting has taken and potential future directions the procedure may yet go.

524 Effectiveness of Burns Wound Cleansing by Comparison of Prewash and Post Wash Swab Reports

2021 ◽  
Vol 108 (Supplement_6) ◽  
Author(s):  
M A Sayed ◽  
S Jabeen ◽  
A Soueid
Keyword(s):  
Bacterial Load ◽  
Total Body Surface Area ◽  
Wound Management ◽  
Burn Patients ◽  
Burn Wound ◽  
Staph Aureus ◽  
Sex Type ◽  
Total Body ◽  
Burns Unit ◽  
Type Of Injury

Abstract Aim The main aim and objective were to optimise wound healing through infection prevention. This clinical audit aimed to investigate the effectiveness of burn wound cleansing in decreasing bacterial load by comparing pre-wash and post-wash swab results against local burn wound management and aseptic non touch technique (ANTT) guidelines. Method The audit was conducted retrospectively on children admitted to Burns Unit during August 2019, excluding resuscitation burn patients. Pre- and post-wash swabs taken on admission were included and the results obtained from Chameleon database. Data were collected on excel spread sheets including demographic variables such as age, sex, type of injury, percentage total body surface area (TBSA) and mechanism of injury. Data were analysed and results compiled. Results Fifty patients were admitted over a month period; amongst those 60% were male and 40% female of ages ranging from 5 months to 14 years. Scald (50%) was found to be the most common mode of injury followed by contact burn (36%) involving 0.30 to 9% TBSA. Among 50 patients, 30 (60%) showed no growth in pre-wash and 36 (72%) in post-wash swabs. However, 6% post-wash swabs that were initially negative later showed bacillus cereus, staph aureus, Enterobacter, and Acinetobacter. Similarly, another 4% post-wash swabs developed new microorganisms as compared to pre-wash swabs. Conclusions The most common bacteria colonising both pre- and post-wash swabs was staph aureus. Overall, cleansing had reduced the bacterial load significantly around 82% very effective. It is imperative to stick to local guidelines to reduce morbidity and mortality in burn patients.

Current status and future outlook of nano‐based systems for burn wound management

2019 ◽  
Vol 108 (5) ◽  
pp. 1934-1952 ◽  
Author(s):  
Morteza Abazari ◽  
Azadeh Ghaffari ◽  
Hamid Rashidzadeh ◽  
Safa Momeni badeleh ◽  
Yaser Maleki
Keyword(s):  
Wound Management ◽  
Current Status ◽  
Burn Wound ◽  
Future Outlook

Advance in burn wound management improves burn survival rate

Burns ◽  
2007 ◽  
Vol 33 (1) ◽  
pp. S16 ◽  
Author(s):  
Yue-Sheng Huang ◽  
P. Yizhi ◽  
L. Xusheng ◽  
L. Xusheng
Keyword(s):  
Survival Rate ◽  
Wound Management ◽  
Burn Wound

Burn wound management

1982 ◽  
Vol 17 (1) ◽  
pp. 95
Author(s):  
L. Rangecroft
Keyword(s):  
Wound Management ◽  
Burn Wound

A reappraisal of the role of cerium in burn wound management

2003 ◽  
Vol 12 (3) ◽  
pp. 113-118 ◽  
Author(s):  
A.B.G. Lansdown ◽  
S.R. Myers ◽  
J.A. Clarke ◽  
P. O'Sullivan
Keyword(s):  
Wound Management ◽  
Burn Wound
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