A novel HPLC method for the determination of zonisamide in human plasma using microextraction by packed sorbent optimised by experimental design

2017 ◽  
Vol 9 (40) ◽  
pp. 5910-5919 ◽  
Author(s):  
Dina Lourenço ◽  
Mafalda Sarraguça ◽  
Gilberto Alves ◽  
Paula Coutinho ◽  
André R. T. S. Araujo ◽  
...  

A novel high-performance liquid chromatography-diode array detection method based on microextraction by packed sorbent as a sample preparation approach was developed and validated for the determination of zonisamide in human plasma.

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