Fluorescent sensors for sodium ions

2017 ◽  
Vol 9 (38) ◽  
pp. 5570-5579 ◽  
Author(s):  
Ge Gao ◽  
Yingli Cao ◽  
Wei Liu ◽  
Dai Li ◽  
Wenhu Zhou ◽  
...  
Keyword(s):  
Small Molecule ◽  
Biological Systems ◽  
Fluorescent Sensors ◽  
Sodium Ions ◽  
Small Molecule Probes

Sodium is a highly important metal in biological systems. Na+sensing can be achieved using small molecule probes, proteins and more recently DNA, and the design of these sensors are summarized.

scholarly journals Two-photon small-molecule fluorescence-based agents for sensing, imaging, and therapy within biological systems

2021 ◽  
Vol 50 (2) ◽  
pp. 702-734
Author(s):  
Luling Wu ◽  
Jihong Liu ◽  
Ping Li ◽  
Bo Tang ◽  
Tony D. James
Keyword(s):  
Small Molecule ◽  
Biological Systems ◽  
Two Photon ◽  
Small Molecule Probes ◽  
Recent Advances ◽  
Design Construction

In this tutorial review, we will explore recent advances for the design, construction and application of two-photon excited fluorescence (TPEF)-based small-molecule probes.

Small-Molecule-Based Fluorescent Sensors for Selective Detection of Reactive Oxygen Species in Biological Systems

2019 ◽  
Vol 88 (1) ◽  
pp. 605-633 ◽  
Author(s):  
Xiaoyu Bai ◽  
Kenneth King-Hei Ng ◽  
Jun Jacob Hu ◽  
Sen Ye ◽  
Dan Yang
Keyword(s):  
Reactive Oxygen Species ◽  
Small Molecule ◽  
Redox Regulation ◽  
Biological Systems ◽  
Reactive Oxygen ◽  
Fluorescent Sensors ◽  
Ros Generation ◽  
Oxygen Species ◽  
Redox Biology ◽  
Health And Disease

Reactive oxygen species (ROS) encompass a collection of intricately linked chemical entities characterized by individually distinct physicochemical properties and biological reactivities. Although excessive ROS generation is well known to underpin disease development, it has become increasingly evident that ROS also play central roles in redox regulation and normal physiology. A major challenge in uncovering the relevant biological mechanisms and deconvoluting the apparently paradoxical roles of distinct ROS in human health and disease lies in the selective and sensitive detection of these transient species in the complex biological milieu. Small-molecule-based fluorescent sensors enable molecular imaging of ROS with great spatial and temporal resolution and have thus been appreciated as excellent tools for aiding discoveries in modern redox biology. We review a selection of state-of-the-art sensors with demonstrated utility in biological systems. By providing a systematic overview based on underlying chemical sensing mechanisms, we wish to highlight the strengths and weaknesses in prior sensor works and propose some guiding principles for the development of future probes.

Controlled self-assembly of small molecule probes and the related applications in bioanalysis

2016 ◽  
Vol 76 ◽  
pp. 38-53 ◽  
Author(s):  
Yongxin Li ◽  
Huipeng Zhou ◽  
Jian Chen ◽  
Sohail Anjum Shahzad ◽  
Cong Yu
Keyword(s):  
Small Molecule ◽  
Self Assembly ◽  
Small Molecule Probes

“Click” synthesis of small molecule probes for activity-based fingerprinting of matrix metalloproteases

2006 ◽  
pp. 3783-3785 ◽  
Author(s):  
Jun Wang ◽  
Mahesh Uttamchandani ◽  
Junqi Li ◽  
Mingyu Hu ◽  
Shao Q. Yao
Keyword(s):  
Small Molecule ◽  
Matrix Metalloproteases ◽  
Small Molecule Probes ◽  
Click Synthesis

Recent progress in the design principles, sensing mechanisms, and applications of small-molecule probes for nitroreductases

2020 ◽  
Vol 421 ◽  
pp. 213460 ◽  
Author(s):  
Ya-Lin Qi ◽  
Long Guo ◽  
Li-Li Chen ◽  
Hua Li ◽  
Yu-Shun Yang ◽  
...  
Keyword(s):  
Small Molecule ◽  
Recent Progress ◽  
Design Principles ◽  
Small Molecule Probes

Selective and Reversible Approaches Toward Imaging Redox Signaling Using Small-Molecule Probes

2016 ◽  
Vol 24 (13) ◽  
pp. 713-730 ◽  
Author(s):  
Jacek L. Kolanowski ◽  
Amandeep Kaur ◽  
Elizabeth J. New
Keyword(s):  
Small Molecule ◽  
Redox Signaling ◽  
Small Molecule Probes
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