Paper test card for detection of adulterated milk

2017 ◽  
Vol 9 (38) ◽  
pp. 5674-5683 ◽  
Author(s):  
Jamie L. Luther ◽  
Valentine Henry de Frahan ◽  
Marya Lieberman

The MilkPAD can colorimetrically detect a variety of starches, urea, glucose, and sucrose with greater than 90% sensitivity and specificity.

2019 ◽  
Vol 11 (37) ◽  
pp. 4727-4732 ◽  
Author(s):  
Sarah L. Bliese ◽  
Mercy Maina ◽  
Phelix Were ◽  
Marya Lieberman
Keyword(s):  

A paper test card can distinguish good quality ceftriaxone from ceftriaxone that has been thermally degraded, adulterated, or falsified.


PLoS ONE ◽  
2017 ◽  
Vol 12 (6) ◽  
pp. e0179716 ◽  
Author(s):  
Nicholas M. Myers ◽  
Ivan C. Leung ◽  
Sean W. McGee ◽  
Kathleen Eggleson ◽  
Marya Lieberman

2018 ◽  
Vol 2018 ◽  
pp. 1-5
Author(s):  
Lifang Zhang ◽  
Yanxia Peng ◽  
Na Jiang ◽  
Lei Shi ◽  
Jieping Lin ◽  
...  

This study was designed to prepare and evaluate the sensitivity and specificity of a Norovirus GI and GII fluorescent particles combined detection test strip method. Using selected chromatographic materials and antibodies specific to Norovirus GI and GII, the Norovirus GI and GII fluorescent particles combined detection test strip (tested method) was prepared as a conventional double antibody sandwich. The samples assayed included cultured rotavirus and 465 specimens from patients with symptoms of gastrointestinal infection. Norovirus was detected using the tested method and a reference method (CerTest Norovirus GI-GII test card). The results indicated that the sensitivity of the tested method was 4 (for GI detection) or 8 times (for GII detection) greater than the reference method. Neither of the two methods cross-reacted with rotavirus and so on. For specimens, 29 were found to be negative by the reference method and positive by the tested method, and 8 were found to be negative by the tested method and positive by the reference method. Furthermore, a retesting of these samples by qPCR showed that 28 of the 29 were positive, and 3 of the 8 were positive. In summary, the Norovirus GI and GII fluorescent particles combined detection test strip was successfully prepared and had good detection performance.


2019 ◽  
Vol 11 (37) ◽  
pp. 4741-4750 ◽  
Author(s):  
Nicholas M. Myers ◽  
Mercy W. Maina ◽  
Phelix Makoto Were ◽  
Rakhi Karwa ◽  
Sonak D. Pastakia ◽  
...  

This paper test card can identify ampicillin or amoxicillin formulations that contain <90% of the stated API content.


10.5772/62919 ◽  
2016 ◽  
Vol 3 ◽  
pp. 5
Author(s):  
Nicholas M. Myers ◽  
Emmerentia Elza Strydom ◽  
James Sweet ◽  
Christopher Sweet ◽  
Rebecca Spohrer ◽  
...  

We created a paper test card that measures a common iodizing agent, iodate, in salt. To test the analytical metrics, usability, and robustness of the paper test card when it is used in low resource settings, the South African Medical Research Council and GroundWork performed independent validation studies of the device. The accuracy and precision metrics from both studies were comparable. In the SAMRC study, more than 90% of the test results (n=1704) were correctly classified as corresponding to adequately or inadequately iodized salt. The cards are suitable for market and household surveys to determine whether salt is adequately iodized. Further development of the cards will improve their utility for monitoring salt iodization during production.


2020 ◽  
Vol 63 (6) ◽  
pp. 1916-1932 ◽  
Author(s):  
Haiying Yuan ◽  
Christine Dollaghan

Purpose No diagnostic tools exist for identifying social (pragmatic) communication disorder (SPCD), a new Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition category for individuals with social communication deficits but not the repetitive, restricted behaviors and interests (RRBIs) that would qualify them for a diagnosis of autism spectrum disorder (ASD). We explored the value of items from a widely used screening measure of ASD for distinguishing SPCD from typical controls (TC; Aim 1) and from ASD (Aim 2). Method We applied item response theory (IRT) modeling to Social Communication Questionnaire–Lifetime ( Rutter, Bailey, & Lord, 2003 ) records available in the National Database for Autism Research. We defined records from putative SPCD ( n = 54), ASD ( n = 278), and TC ( n = 274) groups retrospectively, based on National Database for Autism Research classifications and Autism Diagnostic Interview–Revised responses. After assessing model assumptions, estimating model parameters, and measuring model fit, we identified items in the social communication and RRBI domains that were maximally informative in differentiating the groups. Results IRT modeling identified a set of seven social communication items that distinguished SPCD from TC with sensitivity and specificity > 80%. A set of five RRBI items was less successful in distinguishing SPCD from ASD (sensitivity and specificity < 70%). Conclusion The IRT modeling approach and the Social Communication Questionnaire–Lifetime item sets it identified may be useful in efforts to construct screening and diagnostic measures for SPCD.


2001 ◽  
Vol 120 (5) ◽  
pp. A395-A395
Author(s):  
J WEST ◽  
A LLOYD ◽  
P HILL ◽  
G HOLMES

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