Proton-propelled methyl-tert-butyl ether extraction for highly efficient mass spectrometric analysis of phospholipids in human plasma

2017 ◽  
Vol 9 (31) ◽  
pp. 4491-4495
Author(s):  
Qiuhong Zhou ◽  
Xiaoxue Ye ◽  
Bei Nie
Keyword(s):  
Human Plasma ◽  
Mass Spectrometric ◽  
Mass Spectrometric Analysis ◽  
Methyl Tert Butyl Ether ◽  
Spectrometric Analysis ◽  
Butyl Ether ◽  
Effective Technique ◽  
Tert Butyl ◽  
Ether Extraction ◽  
Multidimensional Separation

Proton-propelled selective phospholipid extraction was found to be a clean and effective technique for mass spectrometric analysis, paving a new avenue for multidimensional separation and isolation with considerable resolution.

Mass spectrometry-based lipidomics analysis using methyl tert-butyl ether extraction in human hepatocellular carcinoma tissues

2015 ◽  
Vol 7 (19) ◽  
pp. 8466-8471 ◽  
Author(s):  
Shuxia Jiang ◽  
Yongle Li ◽  
Shuhai Lin ◽  
Hongbo Yang ◽  
Xin-yuan Guan ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Hepatocellular Carcinoma ◽  
Human Hepatocellular Carcinoma ◽  
Methyl Tert Butyl Ether ◽  
Butyl Ether ◽  
Tert Butyl ◽  
Ether Extraction

Lipidomics was applied to analyse irregular metabolites in HCC tissues through a LC-MS method which revealed great changes between HCT and ANT.

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