AuPd bimetallic nanoparticle-supported carbon nanotubes for selective detection of dopamine in the presence of ascorbic acid

2017 ◽  
Vol 9 (21) ◽  
pp. 3191-3199 ◽  
Author(s):  
Haitang Yang ◽  
Dandan Liu ◽  
Xiaoyu Zhao ◽  
Jing-He Yang ◽  
Haibo Chang ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
Ascorbic Acid ◽  
Electrocatalytic Activity ◽  
Linear Range ◽  
Selective Detection ◽  
Bimetallic Nanoparticle ◽  
Dopamine Oxidation ◽  
High Concentrations

The AuPd/CNTs–Nafion/GCE sensor shows markedly improved and selective electrocatalytic activity towards dopamine oxidation with a linear range from 0.2 to 50 μM in the presence of high concentrations of ascorbic acid in PBS solution at pH 7.0.

PdPt bimetallic alloy nanowires-based electrochemical sensor for sensitive detection of ascorbic acid

RSC Advances ◽  
2016 ◽  
Vol 6 (48) ◽  
pp. 42008-42013 ◽  
Author(s):  
Lihua Jin ◽  
Zaihua Zhang ◽  
Zhihua Zhuang ◽  
Zheng Meng ◽  
Cong Li ◽  
...  
Keyword(s):  
Ascorbic Acid ◽  
Detection Limit ◽  
Electrochemical Sensor ◽  
Electrocatalytic Activity ◽  
Linear Range ◽  
Sensitive Detection ◽  
Wide Linear Range ◽  
Bimetallic Alloy ◽  
Alloy Nanowires

A novel PdPt bimetallic alloy nanowires-based electrochemical sensor for sensitive detection of ascorbic acid with remarkable electrocatalytic activity in a wide linear range (0.01–0.97 mM) and a detection limit as low as 0.2 μM.

Selective Detection of Dopamine in Presence of Ascorbic Acid by Use of Glassy-Carbon Electrode Modified with Amino-β-Cyclodextrin and Carbon Nanotubes

2014 ◽  
Vol 26 (12) ◽  
pp. 2747-2753 ◽  
Author(s):  
Aymen Gaied ◽  
Nejmeddine Jaballah ◽  
Moncef Tounsi ◽  
Mohamed Braiek ◽  
Nicole Jaffrezic-Renault ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
Ascorbic Acid ◽  
Glassy Carbon Electrode ◽  
Glassy Carbon ◽  
Selective Detection ◽  
Carbon Electrode

Molecularly Imprinted Sensor for Ascorbic Acid Based on Gold Nanoparticles and Multiwalled Carbon Nanotubes

2020 ◽  
Vol 16 (7) ◽  
pp. 905-913
Author(s):  
Youyuan Peng ◽  
Qingshan Miao
Keyword(s):  
Carbon Nanotubes ◽  
Gold Nanoparticles ◽  
Ascorbic Acid ◽  
Multiwalled Carbon Nanotubes ◽  
Ph Value ◽  
Biological Fluids ◽  
Water Soluble ◽  
Multiwalled Carbon ◽  
Experimental Conditions ◽  
Molecularly Imprinted

Background: L-Ascorbic acid (AA) is a kind of water soluble vitamin, which is mainly present in fruits, vegetables and biological fluids. As a low cost antioxidant and effective scavenger of free radicals, AA may help to prevent diseases such as cancer and Parkinson’s disease. Owing to its role in the biological metabolism, AA has also been utilized for the therapy of mental illness, common cold and for improving the immunity. Therefore, it is very necessary and urgent to develop a simple, rapid and selective strategy for the detection of AA in various samples. Methods: The molecularly imprinted poly(o-phenylenediamine) (PoPD) film was prepared for the analysis of L-ascorbic acid (AA) on gold nanoparticles (AuNPs) - multiwalled carbon nanotubes (MWCNTs) modified glass carbon electrode (GCE) by electropolymerization of o-phenylenediamine (oPD) and AA. Experimental parameters including pH value of running buffer and scan rates were optimized. Scanning electron microscope (SEM), fourier-transform infrared (FTIR) spectra, cyclic voltammetry (CV) and differential pulse voltammetry (DPV) were utilized for the characterization of the imprinted polymer film. Results: Under the selected experimental conditions, the DPV peak currents of AA exhibit two distinct linear responses ranging from 0.01 to 2 μmol L-1 and 2 to 100 μmol L-1 towards the concentrations of AA, and the detection limit was 2 nmol L-1 (S/N=3). Conclusion: The proposed electrochemical sensor possesses excellent selectivity for AA, along with good reproducibility and stability. The results obtained from the analysis of AA in real samples demonstrated the applicability of the proposed sensor to practical analysis.

High dose ascorbic acid treatment in COVID-19 patients raised some problems in clinical chemistry testing

2020 ◽  
Vol 45 (5) ◽  
pp. 491-498
Author(s):  
Fatih Yesildal ◽  
Ferruh Kemal Isman
Keyword(s):  
Ascorbic Acid ◽  
Ldl Cholesterol ◽  
Clinical Chemistry ◽  
Assay Method ◽  
High Dose ◽  
Serum Samples ◽  
Choice Of Treatment ◽  
High Concentrations ◽  
Clinical Chemistry Tests ◽  
Abbott Architect

AbstractObjectiveCOVID-19 pandemia still continues to threaten the whole world. High dose ascorbic acid (AA) infusion is a choice of treatment and its efficiency is still being investigated. AA interferes with many clinical chemistry tests. However, data about the interference of high concentrations of AA is not sufficient. In this study, we aimed to investigate the interference of AA at high concentrations on commonly used chemistry assays.Materials and MethodsSerum samples at AA concentrations of 200, 150, 100, 75, 50, 25, 10, 5, 2 and 0 mg/dL were prepared by using the stock solution of 15000 mg/dL AA. Each sample was analyzed by using the most common 30 chemistry tests (Abbott Architect C8000, Illinois, USA) and a POCT glucometer (STANDARD GlucoNavii, Gyeonggi-do, Republic of Korea).ResultsCreatinine, sodium and glucose (POCT) tests were found to be positively interfered by increasing AA concentrations; while direct bilirubin, lipase, UIBC, triglyceride, total cholesterol, HDL/LDL cholesterol tests were negatively interfered. Absolute interference (%) increased as the AA concentration increased.ConclusionThis is the largest and first study to investigate the interference of high dose AA, which is used in severe COVID-19 patients nowadays. Manufacturers and clinicians should be aware of the possibility of aberrant results due to high dose AA infusion. Clinicians should not forget to consult a laboratory specialist, since he is the only person to monitor the reactions in all assays, and know the technical subjects like interferences, assay method specifications. This issue is very important for correct decision-making and interpretation of the data-mining studies accurately and efficiently.

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