Supercritical fluid (CO2) chromatography for quantitative determination of selected cancer therapeutic drugs in the prescence of potential impurities in injection formulations

2017 ◽  
Vol 9 (20) ◽  
pp. 3003-3018 ◽  
Author(s):  
Venkata Narasimha Rao G. ◽  
Ravi B. ◽  
Jalandhar D. ◽  
Manoj P. ◽  
R. Venkata Nadh
Keyword(s):  
Quantitative Determination ◽  
Supercritical Fluid ◽  
Supercritical State ◽  
Therapeutic Drugs ◽  
Supercritical Fluid Co2

In the present study, two cancer therapeutic drugs (docetaxel and bortezomib) were separated from their potential impurities on a chromatographic platform by utilizing CO2 gas (supercritical state) and quantified.

Supercritical fluid (CO2) chromatography for quantitative determination of selected cancer therapeutic drugs in the presence of potential impurities

2015 ◽  
Vol 7 (3) ◽  
pp. 1092-1097 ◽  
Author(s):  
Venkata Narasimha Rao Ganipisetty ◽  
B. Ravi ◽  
Ch. Rajsekhara Reddy ◽  
RajKumar Gurjar ◽  
P. Manoj ◽  
...  
Keyword(s):  
Quantitative Determination ◽  
Supercritical Fluid ◽  
Chromatographic Methods ◽  
Therapeutic Drugs ◽  
System P ◽  
Supercritical Fluid Co2

In the present study, supercritical fluid (CO2) chromatographic methods were validated for the estimation of two cancer therapeutic drugs, fulvestrant and azacitidine, using UPC2system.

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