Two orders of magnitude electrokinetic stacking of proteins in one minute on a simple paper fluidic channel

2017 ◽  
Vol 9 (18) ◽  
pp. 2703-2709 ◽  
Author(s):  
Biao Ma ◽  
Song-Fang Xie ◽  
Lei Liu ◽  
Fang Fang ◽  
Zhi-Yong Wu
Keyword(s):  
Bovine Hemoglobin ◽  
Fluidic Channel ◽  
Model Protein ◽  
Stacking Effect ◽  
Electrokinetic Stacking ◽  
Analytical Device

New insights were brought into the field amplified stacking effect implemented on a paper-based analytical device, and a model protein of bovine hemoglobin was 150-fold stacked within 60 sec.

Highly efficient sample stacking by enhanced field amplification on a simple paper device

Lab on a Chip ◽  
2016 ◽  
Vol 16 (18) ◽  
pp. 3460-3465 ◽  
Author(s):  
Biao Ma ◽  
Yi-Zhen Song ◽  
Ji-Cheng Niu ◽  
Zhi-Yong Wu
Keyword(s):  
Sample Stacking ◽  
Highly Efficient ◽  
Field Amplification ◽  
Paper Device ◽  
Signal Improvement ◽  
Electrokinetic Stacking ◽  
Analytical Device

Electrokinetic stacking based on field amplification was firstly introduced to a paper-based analytical device, and over 1000-fold signal improvement was achieved.

Fast and highly efficient multiplexed electrokinetic stacking on a paper-based analytical device

2021 ◽  
pp. 107041
Author(s):  
Yu-Qi Liu ◽  
Bin Ji ◽  
Xiang-Hong Yan ◽  
Shuang Lv ◽  
Fang Fang ◽  
...  
Keyword(s):  
Highly Efficient ◽  
Electrokinetic Stacking ◽  
Analytical Device

Simultaneous electrokinetic stacking and separation of anionic and cationic species on a paper fluidic channel

Lab on a Chip ◽  
2019 ◽  
Vol 19 (5) ◽  
pp. 845-850 ◽  
Author(s):  
Lei Liu ◽  
Mao-Rong Xie ◽  
Yu-Zhu Chen ◽  
Zhi-Yong Wu
Keyword(s):  
Fluidic Channel ◽  
Amplification Effect ◽  
Cationic Species ◽  
Field Amplification ◽  
Electrokinetic Stacking

Both anionic and cationic species can be simultaneously stacked and separated on a paper fluidic channel based on field amplification effect.

DEVELOPMENT OF MAGNETICALLY RESPONSIVE Fe3O4@C CORE/SHELL MICROSPHERES AS POTENTIAL VECTORS FOR DRUG-DELIVERY APPLICATIONS

NANO ◽  
2013 ◽  
Vol 08 (04) ◽  
pp. 1350039 ◽  
Author(s):  
WENJING YUAN ◽  
LING ZHU ◽  
PING CHEN ◽  
ANJIAN XIE ◽  
HUI ZHANG ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Electron Microscope ◽  
Nitrogen Adsorption ◽  
Mesoporous Structure ◽  
Bet Surface Area ◽  
Core Shell ◽  
Bovine Hemoglobin ◽  
Hydrothermal Route ◽  
Model Protein ◽  
Adsorption Desorption

The Fe3O4@C core/shell microspheres were fabricated via a two-step process. Fe3O4 microspheres were firstly prepared, and Fe3O4@C core/shell microspheres were subsequently fabricated using glucose as a carbon source by a hydrothermal route, in which the thickness of the carbon coating was about 20 nm. The resulting products were characterized by scanning electron microscope (SEM), transmission electron microscope (TEM), X-ray diffraction (XRD) and Fourier transform infrared spectra (FTIR). The Nitrogen adsorption–desorption isotherms reveal their mesoporous structure and larger BET surface area (62.3 m2g-1). The Fe3O4@C core/shell microspheres possess ferromagnetism and high saturation magnetization (39.2 emu ⋅ g-1). Bovine hemoglobin (BHb) was used as a model protein to test the adsorption and desorption properties of the Fe3O4@C core/shell microspheres. The capacity for BHb adsorption was more than 71.3 mg/g. According to the values obtained in the MTT (3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide) assay the Fe3O4@C core/shell microspheres show a low toxicity. Therefore, the prepared Fe3O4@C core/shell microspheres are of great significance for guided site-specific drug delivery.

Electrokinetic stacking of electrically neutral analytes with paper-based analytical device

Talanta ◽  
2018 ◽  
Vol 182 ◽  
pp. 247-252 ◽  
Author(s):  
Yi-Zhen Song ◽  
Xiu-Xiu Zhang ◽  
Jia-Juan Liu ◽  
Fang Fang ◽  
Zhi-Yong Wu
Keyword(s):  
Electrokinetic Stacking ◽  
Analytical Device ◽  
Neutral Analytes
Sign in / Sign up

Export Citation Format

Share Document