A smartphone-based double-channel fluorescence setup for immunoassay of a carcinoembryonic antigen using CuS nanoparticles for signal amplification

The Analyst ◽  
2018 ◽  
Vol 143 (7) ◽  
pp. 1670-1678 ◽  
Author(s):  
Honghai Wang ◽  
Yan Sun ◽  
Weiwei Yue ◽  
Qi Kang ◽  
Huijuan Li ◽  
...  
Keyword(s):  
Carcinoembryonic Antigen ◽  
Clinical Diagnosis ◽  
Signal Amplification ◽  
Cancer Biomarkers ◽  
Sensitive Detection ◽  
Diagnosis And Treatment ◽  
Treatment Assessment ◽  
Double Channel

Sensitive detection of cancer biomarkers is valuable for clinical diagnosis and treatment assessment of cancers.

Extracellular Vesicles in Tumor Diagnosis: A Mini-Review

2020 ◽  
Vol 20 ◽  
Author(s):  
Si Yu ◽  
Menglin Huang ◽  
Jingyu Wang ◽  
Yongchang Zheng ◽  
Haifeng Xu
Keyword(s):  
Clinical Diagnosis ◽  
Sensitivity And Specificity ◽  
Cancer Diagnosis ◽  
Cancer Biomarkers ◽  
Related Substances ◽  
Physiological Processes ◽  
Cancer Pathogenesis ◽  
Limited Application ◽  
Low Sensitivity ◽  
Shed Light

: Widely exploration of noninvasive tumor/cancer biomarkers has shed light on clinical diagnosis. However, many under-investigated biomarkers showed limited application potency due to low sensitivity and specificity, while extracellular vehicles (EVs) were gradually recognized as promising candidates. EVs are small vesicles transporting bioactive cargos between cells in multiple physiological processes and also in tumor/cancer pathogenesis. This review aimed to offer recent studies of EVs on structure, classification, physiological functions, as well as changes in tumor initiation and progression. Furthermore, we focused on advances of EVs and/or EV-related substances in cancer diagnosis, and summarized ongoing studies of promising candidates for future investigations.

A DNAzyme-catalyzed label-free aptasensor based on multifunctional dendrimer-like DNA assembly for sensitive detection of carcinoembryonic antigen

2021 ◽  
Vol 194 ◽  
pp. 113618
Author(s):  
Xiao-Jing Zhai ◽  
Qiong-Lin Wang ◽  
Hui-Fang Cui ◽  
Xiaojie Song ◽  
Qi-Yan Lv ◽  
...  
Keyword(s):  
Carcinoembryonic Antigen ◽  
Sensitive Detection ◽  
Dna Assembly ◽  
Label Free

scholarly journals Carcinoembryonic Antigen Elevation in a Patient with SARS-CoV-2 and a History of Colon Cancer

2021 ◽  
pp. 802-805
Author(s):  
Taha Alrifai ◽  
Anita Sharko ◽  
William T. Leslie
Keyword(s):  
Health Care ◽  
Colon Cancer ◽  
Severe Acute Respiratory Syndrome ◽  
Carcinoembryonic Antigen ◽  
Health Care Delivery ◽  
Care Delivery ◽  
Prognostic Biomarkers ◽  
Diagnosis And Treatment ◽  
Routine Surveillance ◽  
History Of

The severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) pandemic continues to affect millions of people and impact health-care delivery worldwide. New data and insights into the diagnosis and treatment of SARS-CoV-2 are emerging rapidly. Several prognostic biomarkers have been studied in patients with SARS-CoV-2. Among those biomarkers is the carcinoembryonic antigen (CEA). We report the case of a 46-year-old male with a history of colon cancer who was found to have an elevated CEA level during routine surveillance. Further workup confirmed a diagnosis of SARS-CoV-2 infection. The CEA level normalized with the resolution of the infection.

scholarly journals Epidemiological Distribution and Subtype Analysis of Premenstrual Dysphoric Disorder Syndromes and Symptoms Based on TCM Theories

2017 ◽  
Vol 2017 ◽  
pp. 1-9 ◽  
Author(s):  
Mingqi Qiao ◽  
Peng Sun ◽  
Haijun Wang ◽  
Yang Wang ◽  
Xianghong Zhan ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Clinical Diagnosis ◽  
Premenstrual Dysphoric Disorder ◽  
Diagnosis And Treatment ◽  
Epidemiological Investigation ◽  
Different Types

We performed an epidemiological investigation of subjects with premenstrual dysphoric disorder (PMDD) to identify the clinical distribution of the major syndromes and symptoms. The pathogenesis of PMDD mainly involves the dysfunction of liver conveyance and dispersion. Excessive liver conveyance and dispersion are associated with liver-qi invasion syndrome, while insufficient liver conveyance and dispersion are expressed as liver-qi depression syndrome. Additionally, a nonconditional logistic regression was performed to analyze the symptomatic features of liver-qi invasion and liver-qi depression. As a result of this analysis, two subtypes of PMDD are proposed, namely, excessive liver conveyance and dispersion (liver-qi invasion syndrome) and insufficient liver conveyance and dispersion (liver-qi depression syndrome). Our findings provide an epidemiological foundation for the clinical diagnosis and treatment of PMDD based on the identification of different types.

A highly sensitive fluorescence biosensor for detection of Staphylococcus aureus based on HCR-mediated three-way DNA junction nicking enzyme assisted signal amplification

The Analyst ◽  
2021 ◽  
Author(s):  
Chuyan Zhang ◽  
Zewei Luo ◽  
Mengfan Wu ◽  
Wei Ning ◽  
Ziyi Tian ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Food Safety ◽  
Signal Amplification ◽  
Sensitive Detection ◽  
Safety Control ◽  
Food Borne ◽  
Highly Sensitive ◽  
Fluorescence Biosensor ◽  
Highly Sensitive Detection ◽  
Nicking Enzyme

Sensitive and efficient monitoring of food-borne bacteria is of great importance for food safety control. Herein, a novel biosensor for highly sensitive detection of Staphylococcus aureus (S. aureus) was constructed...

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