Nanoporous anodic aluminum oxide internalized with gold nanoparticles for on-chip PCR and direct detection by surface-enhanced Raman scattering

The Analyst ◽  
2018 ◽  
Vol 143 (4) ◽  
pp. 808-812 ◽  
Author(s):  
B. M. Tran ◽  
N. N. Nam ◽  
S. J. Son ◽  
N. Y. Lee

Nanoporous anodic aluminum oxide (AAO) internalized with gold nanoparticles was utilized as an integrated platform miniaturized for consecutively performing on-chip PCR and downstream detection of the target DNA amplicons using surface-enhanced Raman scattering (SERS).

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