Fabrication and characterization of electrospun nanofibers composed of decellularized meniscus extracellular matrix and polycaprolactone for meniscus tissue engineering

2017 ◽  
Vol 5 (12) ◽  
pp. 2273-2285 ◽  
Author(s):  
Shuang Gao ◽  
Weimin Guo ◽  
Mingxue Chen ◽  
Zhiguo Yuan ◽  
Mingjie Wang ◽  
...  

Decellularized meniscus extracellular matrix (DMECM) and polycaprolactone (PCL) were electrospun into nanofibers to make meniscus scaffolds with good mechanical properties.

RSC Advances ◽  
2016 ◽  
Vol 6 (112) ◽  
pp. 110557-110565 ◽  
Author(s):  
Yinxian Yu ◽  
Sha Hua ◽  
Mengkai Yang ◽  
Zeze Fu ◽  
Songsong Teng ◽  
...  

A composite scaffold was fabricated with a method involving both electrospinning and 3D printing to give microscale pores and good mechanical properties. Biocompatibility and cell infiltration on the scaffold was evaluated by an in vitro study.


2014 ◽  
Vol 695 ◽  
pp. 195-198
Author(s):  
Lor Huai Chong ◽  
Mim Mim Lim ◽  
Naznin Sultana

Tissue engineering (TE) provides an alternative option to solve limitation of organ and tissue transplantation issues. Fabrication of scaffold is a major challenge because it needs to provide a suitable medium for cell growing and drug delivery which enhances cell transplantation efficiency. The porosity, biodegradability and biocompatibility are the important properties in fabricating a scaffold. Our previous work had found that electrospinning of Polycarprolactone (PCL)/ Gelatin (GE)-based nanofibers in 14% w/v polymer solution in 18kV showed the best results in morphology, average diameters, average pore size and hydrophilicity. Hence, in this project, we are interested to study the relationship between weight ratio of PCL and GE in the same concentration (14%) to the morphology, degradation rate and porosity of nanofibers. Experimental results showed that PCL with 1.2g and GE with 0.2g was able to produce better nanofibers. The sample was then further deployed in drug (tetracycline hydrochloride) loading and it was successfully loaded proven by Energy Dispersive X-Ray (EDX) Spectrum. These nanofibers are predicted to be potentially useful for drug delivery and TE application.


2021 ◽  
pp. 50547
Author(s):  
Shabnam Shokraei ◽  
Esmaeil Mirzaei ◽  
Nasim Shokraei ◽  
Mohammad Ali Derakhshan ◽  
Hossein Ghanbari ◽  
...  

2015 ◽  
Vol 1105 ◽  
pp. 51-55 ◽  
Author(s):  
K.M. Gupta ◽  
Kishor Kalauni

Bhimal fibres are quite a newer kind of bio-degradable fibres. They have never been heard before in literatures from the view point of their utility as engineering material. These fibres have been utilized for investigation of their properties. Characterization of this fibre is essential to determine its properties for further use as reinforcing fibre in polymeric, bio-degradable and other kinds of matrix. With this objective, the fabrication method and other mechanical properties of Bhimal-reinforced-PVA biocomposite have been discussed. The stress-strain curves and load-deflection characteristics are obtained. The tensile, compressive, flexure and impact strengths have been calculated. The results are shown in tables and graphs. The results obtained are compared with other existing natural fibre biocomposites. From the observations, it has been concluded that the tensile strength of Bhimal-reinforced-PVA biocomposite is higher than other natural fibre composites. Hence these can be used as reinforcement to produce much lighter weight biocomposites.


2011 ◽  
Vol 12 (3) ◽  
pp. 345-351 ◽  
Author(s):  
Chaorong Li ◽  
Rui Chen ◽  
Xiaoqiang Zhang ◽  
Jie Xiong ◽  
Yingying Zheng ◽  
...  

Vacuum ◽  
2016 ◽  
Vol 128 ◽  
pp. 230-233 ◽  
Author(s):  
Wei Li ◽  
Jia Meng ◽  
Ping Liu ◽  
Haoming Du ◽  
Ke Zhang ◽  
...  

Author(s):  
Miguel R. Matus-Muñoz ◽  
Rubén Ruiz-Ramos ◽  
Víctor Altuzar ◽  
Hiram Isaac Beltrán ◽  
Martha A. Palomino-Ovando ◽  
...  

2016 ◽  
Vol 7 (14) ◽  
pp. 2553-2564 ◽  
Author(s):  
Yating Jia ◽  
Weizhong Wang ◽  
Xiaojun Zhou ◽  
Wei Nie ◽  
Liang Chen ◽  
...  

A poly(glycerol sebacate)-based elastomeric copolyesters with improved mechanical properties and higher water uptake capacity.


2014 ◽  
Vol 40 (5) ◽  
pp. 6405-6411 ◽  
Author(s):  
Abbas Teimouri ◽  
Leila Ghorbanian ◽  
Alireza Najafi Chermahini ◽  
Rahmatollah Emadi

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