Tumor marker detection using surface enhanced Raman spectroscopy on 3D Au butterfly wings

2017 ◽  
Vol 5 (8) ◽  
pp. 1594-1600 ◽  
Author(s):  
Guofen Song ◽  
Han Zhou ◽  
Jiajun Gu ◽  
Qinglei Liu ◽  
Wang Zhang ◽  
...  

Tumor markers are usually over-expressed in human body fluids during the development of cancers.

2020 ◽  
Vol 3 (11) ◽  
pp. 8012-8022
Author(s):  
Ying Chen ◽  
Hongmei Liu ◽  
Jiamin Jiang ◽  
Chenjie Gu ◽  
Ziqi Zhao ◽  
...  

2019 ◽  
Vol 7 (44) ◽  
pp. 13887-13895 ◽  
Author(s):  
Levi D. Palmer ◽  
James L. Brooks ◽  
Renee R. Frontiera

The photonic architectures of butterfly wings selectively increase surface-enhanced Raman scattering and we quantitate the enhancement of this photonic–plasmonic interaction.


2021 ◽  
Vol 9 ◽  
Author(s):  
Aleksandra Szaniawska ◽  
Andrzej Kudelski

In this mini-review, we briefly describe certain recently developed applications of the surface-enhanced Raman spectroscopy (SERS) for determining various biochemically (especially medically) important species from ones as simple as hydrogen cations to those as complex as specific DNA fragments. We present a SERS analysis of species whose characterization is important to our understanding of various mechanisms in the human body and to show its potential as an alternative for methods routinely used in diagnostics and clinics. Furthermore, we explain how such SERS-based sensors operate and point out future prospects in this field.


2015 ◽  
Vol 7 (16) ◽  
pp. 6489-6495 ◽  
Author(s):  
Ming Ge ◽  
Chao Wei ◽  
Minmin Xu ◽  
Congwei Fang ◽  
Yaxian Yuan ◽  
...  

Human epididymis protein 4 (HE4), as a serological marker, has been proposed to be the most promising tumor marker in ovarian cancer diagnosis.


2017 ◽  
Author(s):  
Caitlin S. DeJong ◽  
David I. Wang ◽  
Aleksandr Polyakov ◽  
Anita Rogacs ◽  
Steven J. Simske ◽  
...  

Through the direct detection of bacterial volatile organic compounds (VOCs), via surface enhanced Raman spectroscopy (SERS), we report here a reconfigurable assay for the identification and monitoring of bacteria. We demonstrate differentiation between highly clinically relevant organisms: <i>Escherichia coli</i>, <i>Enterobacter cloacae</i>, and <i>Serratia marcescens</i>. This is the first differentiation of bacteria via SERS of bacterial VOC signatures. The assay also detected as few as 10 CFU/ml of <i>E. coli</i> in under 12 hrs, and detected <i>E. coli</i> from whole human blood and human urine in 16 hrs at clinically relevant concentrations of 10<sup>3</sup> CFU/ml and 10<sup>4</sup> CFU/ml, respectively. In addition, the recent emergence of portable Raman spectrometers uniquely allows SERS to bring VOC detection to point-of-care settings for diagnosing bacterial infections.


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