Mixed micelles obtained by co-assembling comb-like and grafting copolymers as gene carriers for efficient gene delivery and expression in endothelial cells

2017 ◽  
Vol 5 (8) ◽  
pp. 1673-1687 ◽  
Author(s):  
Qian Li ◽  
Xuefang Hao ◽  
Juan Lv ◽  
Xiangkui Ren ◽  
Kunyu Zhang ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Gene Delivery ◽  
Mixed Micelles ◽  
Gene Carriers ◽  
Efficient Gene

Ligand targeting and peptide functionalized polymers as non-viral carriers for gene therapy

2020 ◽  
Vol 8 (1) ◽  
pp. 64-83 ◽  
Author(s):  
Khan Muhammad ◽  
Jing Zhao ◽  
Ihsan Ullah ◽  
Jintang Guo ◽  
Xiang-kui Ren ◽  
...  
Keyword(s):  
Gene Therapy ◽  
Gene Delivery ◽  
Functionalized Polymers ◽  
Gene Carriers ◽  
Efficient Gene

Ligand targeting and peptide functionalized polymers serve as gene carriers for efficient gene delivery.

Amino acids functionalized dendrimers with nucleus accumulation for efficient gene delivery

2021 ◽  
pp. 120641
Author(s):  
Guoxin Tan ◽  
Jiayang Li ◽  
Dandan Liu ◽  
Hao Pan ◽  
Renfang Zhu ◽  
...  
Keyword(s):  
Amino Acids ◽  
Gene Delivery ◽  
Efficient Gene

scholarly journals Carbon Dot Nanoparticles: Exploring the Potential Use for Gene Delivery in Ophthalmic Diseases

Nanomaterials ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 935
Author(s):  
Manas R. Biswal ◽  
Sofia Bhatia
Keyword(s):  
Gene Delivery ◽  
Therapeutic Option ◽  
Retinal Dystrophy ◽  
Retinal Cells ◽  
Adeno Associated Virus ◽  
Inherited Retinal Dystrophies ◽  
Retinal Dystrophies ◽  
Efficient Gene ◽  
New Type ◽  
Viral Nanoparticles

Ocular gene therapy offers significant potential for preventing retinal dystrophy in patients with inherited retinal dystrophies (IRD). Adeno-associated virus (AAV) based gene transfer is the most common and successful gene delivery approach to the eye. These days, many studies are using non-viral nanoparticles (NPs) as an alternative therapeutic option because of their unique properties and biocompatibility. Here, we discuss the potential of carbon dots (CDs), a new type of nanocarrier for gene delivery to the retinal cells. The unique physicochemical properties of CDs (such as optical, electronic, and catalytic) make them suitable for biosensing, imaging, drug, and gene delivery applications. Efficient gene delivery to the retinal cells using CDs depends on various factors, such as photoluminescence, quantum yield, biocompatibility, size, and shape. In this review, we focused on different approaches used to synthesize CDs, classify CDs, various pathways for the intake of gene-loaded carbon nanoparticles inside the cell, and multiple studies that worked on transferring nucleic acid in the eye using CDs.

Polyethylenimine-poly(amidoamine) dendrimer modified with l-arginines as an efficient gene delivery vector

2015 ◽  
Vol 23 (8) ◽  
pp. 726-733 ◽  
Author(s):  
Nan Young Ahn ◽  
Tae-Hun Kim ◽  
Su Jeong Song ◽  
Jeong-Mi Moon ◽  
Tai Hwan Ha ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Gene Delivery Vector ◽  
Delivery Vector ◽  
Efficient Gene

pH-Sensitive Pentablock Copolymer Nanocapsules as Nontoxic and Efficient Gene Carriers

2011 ◽  
Vol 11 (6) ◽  
pp. 789-796 ◽  
Author(s):  
Min Sang Lee ◽  
Yeon Lim Jang ◽  
Dai Phu Huynh ◽  
Cong Truc Huynh ◽  
Yuhan Lee ◽  
...  
Keyword(s):  
Ph Sensitive ◽  
Gene Carriers ◽  
Efficient Gene ◽  
Pentablock Copolymer

scholarly journals Efficient gene delivery and silencing of mouse and human pancreatic islets

2010 ◽  
Vol 10 (1) ◽  
pp. 28 ◽  
Author(s):  
Bruno Lefebvre ◽  
Brigitte Vandewalle ◽  
Justine Longue ◽  
Ericka Moerman ◽  
Bruno Lukowiak ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Pancreatic Islets ◽  
Human Pancreatic Islets ◽  
Efficient Gene

Efficient gene delivery using chitosan–polyethylenimine hybrid systems

2008 ◽  
Vol 3 (2) ◽  
pp. 025013 ◽  
Author(s):  
Hu-Lin Jiang ◽  
Tae-Hee Kim ◽  
You-Kyoung Kim ◽  
In-Young Park ◽  
Myung-Haing Cho ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Hybrid Systems ◽  
Efficient Gene
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