In situ forming gelatin hydrogels by dual-enzymatic cross-linking for enhanced tissue adhesiveness

2017 ◽  
Vol 5 (4) ◽  
pp. 757-764 ◽  
Author(s):  
Phuong Le Thi ◽  
Yunki Lee ◽  
Dai Hai Nguyen ◽  
Ki Dong Park
Keyword(s):  
Biomedical Applications ◽  
Cross Linking ◽  
In Situ Forming ◽  
Wide Range

In situ forming hydrogels show promise as therapeutic implants and carriers in a wide range of biomedical applications.

Introduction to In Situ Forming Hydrogels for Biomedical Applications

2014 ◽  
pp. 5-35 ◽  
Author(s):  
Bogyu Choi ◽  
Xian Jun Loh ◽  
Aloysius Tan ◽  
Chun Keat Loh ◽  
Enyi Ye ◽  
...  
Keyword(s):  
Biomedical Applications ◽  
In Situ Forming ◽  
In Situ Forming Hydrogels

scholarly journals In situ forming IPN hydrogels of calcium alginate and dextran-HEMA for biomedical applications

2011 ◽  
Vol 7 (4) ◽  
pp. 1627-1633 ◽  
Author(s):  
Laura Pescosolido ◽  
Tina Vermonden ◽  
Jos Malda ◽  
Roberta Censi ◽  
Wouter J.A. Dhert ◽  
...  
Keyword(s):  
Calcium Alginate ◽  
Biomedical Applications ◽  
In Situ Forming

Enzyme-mediated cross-linking of Pluronic copolymer micelles for injectable and in situ forming hydrogels

2011 ◽  
Vol 7 (4) ◽  
pp. 1468-1476 ◽  
Author(s):  
Soo Hyeon Lee ◽  
Yuhan Lee ◽  
Sang-Woo Lee ◽  
Ha-Yeun Ji ◽  
Ji-Hee Lee ◽  
...  
Keyword(s):  
Cross Linking ◽  
In Situ Forming ◽  
Copolymer Micelles ◽  
In Situ Forming Hydrogels

Polymeric in situ forming systems for biomedical applications. Part II. Injectable hydrogel systems

Polimery ◽  
2015 ◽  
Vol 60 (07/08) ◽  
pp. 435-447 ◽  
Author(s):  
Anna Korytkowska-Walach ◽  
Monika Smiga-Matuszowicz ◽  
Jan Lukaszczyk
Keyword(s):  
Biomedical Applications ◽  
Injectable Hydrogel ◽  
In Situ Forming

Potential of Electrospun Graphene Oxide-Gelatin Composite Nanofibers for Biomedical Applications

2015 ◽  
Vol 830-831 ◽  
pp. 581-584
Author(s):  
K Jalaja ◽  
R. James Nirmala
Keyword(s):  
Graphene Oxide ◽  
Polymer Matrix ◽  
Biomedical Applications ◽  
Composite Nanofibers ◽  
Water Resistance ◽  
Mechanical Performance ◽  
Cross Linking ◽  
Reinforcing Effect ◽  
Wide Range ◽  
Versatile Technique

Graphene oxide incorporated polymer matrix provides a multifunctional facet due to the reinforcing effect of graphene oxide (GO) with wide range of properties. Nanofibers are fabricated by a versatile technique known as electrospinning. The present study demonstrates the fabrication of gelatin, a protein nanofibers non-covalently functionalized with GO. The effect of GO on gelatin nanofibers in terms of mechanical performance is studied. In order to improve the water resistance of the resulting nanofibers, cross-linking is performed using dextran aldehyde.

In Situ Forming Chitosan Hydrogels Prepared via Ionic/Covalent Co-Cross-Linking

2011 ◽  
Vol 12 (9) ◽  
pp. 3275-3284 ◽  
Author(s):  
M. José Moura ◽  
H. Faneca ◽  
M. Pedroso Lima ◽  
M. Helena Gil ◽  
M. Margarida Figueiredo
Keyword(s):  
Cross Linking ◽  
In Situ Forming ◽  
Chitosan Hydrogels

scholarly journals In situ crosslinkable hydrogels for engineered cellular microenvironments

2017 ◽  
Vol 19 (3) ◽  
pp. 53-64
Author(s):  
Kyung Min Park ◽  
Ki Dong Park ◽  
V. I. Sevastianov ◽  
E. A. Nemetz ◽  
V. N. Vasilets
Keyword(s):  
Extracellular Matrix ◽  
Biomedical Applications ◽  
Structural Similarity ◽  
Biological Properties ◽  
In Situ Forming ◽  
Physical Chemical ◽  
Cellular Microenvironments ◽  
Artificial Extracellular Matrix ◽  
In Situ Forming Hydrogels

In situ crosslinkable hydrogels have been widely used as therapeutic implants and vehicles for a broad range of biomedical applications including tissue regenerative medicine because of their biocompatibility and easiness of encapsulation of cells or signaling molecules during hydrogel formation. Recently, these hydrogel materials have been widely utilized as an artificial extracellular matrix (aECM) because of its structural similarity with the native extracellular matrix (ECM) of the human body and its multi-tunable properties. Various synthetic, natural, and semisynthetic hydrogels have been developed as engineered cellular microenvironments by using various crosslinking strategies. In this review, we discuss how in situ forming hydrogels are being created with tunable physical, chemical, and biological properties. In particular, we focus on emerging techniques to apply advanced hydrogel materials for engineered cellular microenvironments.

Synthesis and Characterization of an Enzyme Mediated in situ Forming Hydrogel Based on Gum Tragacanth for Biomedical Applications

2014 ◽  
Vol 12 (1) ◽  
Author(s):  
Moslem Tavakol ◽  
Ebrahim Vasheghani-Farahani ◽  
Masoud Soleimani ◽  
Mohammad Amin Mohammadifar ◽  
Sameereh Hashemi-Najafabadi ◽  
...  
Keyword(s):  
Biomedical Applications ◽  
Synthesis And Characterization ◽  
Gum Tragacanth ◽  
In Situ Forming
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