scholarly journals β-Hairpin mimics containing a piperidine–pyrrolidine scaffold modulate the β-amyloid aggregation process preserving the monomer species

2017 ◽  
Vol 8 (2) ◽  
pp. 1295-1302 ◽  
Author(s):  
S. Pellegrino ◽  
N. Tonali ◽  
E. Erba ◽  
J. Kaffy ◽  
M. Taverna ◽  
...  
Keyword(s):  
Protein Interactions ◽  
Amyloid Β ◽  
Amyloid Β Peptide ◽  
Peptide Aggregation ◽  
Aggregation Process ◽  
Amyloid Aggregation ◽  
Protein Protein Interactions ◽  
Β Amyloid

Acyclic β-hairpins designed on oligomeric and fibril structures of Aβ1–42 disrupt protein–protein interactions mediating amyloid β-peptide aggregation.

Specific Binding of a β-Cyclodextrin Dimer to the Amyloid β Peptide Modulates the Peptide Aggregation Process

Biochemistry ◽  
2012 ◽  
Vol 51 (21) ◽  
pp. 4280-4289 ◽  
Author(s):  
Anna Wahlström ◽  
Risto Cukalevski ◽  
Jens Danielsson ◽  
Jüri Jarvet ◽  
Hideki Onagi ◽  
...  
Keyword(s):  
Specific Binding ◽  
Amyloid Β ◽  
Amyloid Β Peptide ◽  
Peptide Aggregation ◽  
Aggregation Process ◽  
Cyclodextrin Dimer

The effect of β-sheet breaker peptides on metal associated Amyloid-β peptide aggregation process

2017 ◽  
Vol 229 ◽  
pp. 110-114 ◽  
Author(s):  
F. Stellato ◽  
Z. Fusco ◽  
R. Chiaraluce ◽  
V. Consalvi ◽  
S. Dinarelli ◽  
...  
Keyword(s):  
Amyloid Β ◽  
Amyloid Β Peptide ◽  
Peptide Aggregation ◽  
Aggregation Process ◽  
Β Sheet

Direct electrochemical and AFM detection of amyloid-β peptide aggregation on basal plane HOPG

Nanoscale ◽  
2014 ◽  
Vol 6 (14) ◽  
pp. 7853-7857 ◽  
Author(s):  
Paula Lopes ◽  
Meng Xu ◽  
Min Zhang ◽  
Ting Zhou ◽  
Yanlian Yang ◽  
...  
Keyword(s):  
Basal Plane ◽  
Amyloid Β ◽  
Electrochemical Characterization ◽  
Amyloid Peptide ◽  
Amyloid Β Peptide ◽  
Peptide Aggregation ◽  
Β Amyloid ◽  
Β Amyloid Peptide ◽  
First Time

AFM and electrochemical characterization of β-amyloid peptide aggregation was for the first time performed on the same substrate thus enabling advanced screening of amyloidosis progression.

Modulation of amyloid β peptide aggregation by hydrophilic polymers

2019 ◽  
Vol 21 (37) ◽  
pp. 20999-21006
Author(s):  
Zhanna Evgrafova ◽  
Bruno Voigt ◽  
Andreas H. Roos ◽  
Gerd Hause ◽  
Dariush Hinderberger ◽  
...  
Keyword(s):  
Amyloid Β ◽  
Hydrophilic Polymers ◽  
Amyloid Β Peptide ◽  
Peptide Aggregation ◽  
Amyloidogenic Protein

Careful balance of hydrophilicity of precisely engineered polymers alters aggregation of the amyloidogenic protein Aβ1–40.

scholarly journals Inhibition of Glycosphingolipid Biosynthesis Reduces Secretion of the β-Amyloid Precursor Protein and Amyloid β-Peptide

2005 ◽  
Vol 280 (30) ◽  
pp. 28110-28117 ◽  
Author(s):  
Irfan Y. Tamboli ◽  
Kai Prager ◽  
Esther Barth ◽  
Michael Heneka ◽  
Konrad Sandhoff ◽  
...  
Keyword(s):  
Amyloid Precursor Protein ◽  
Amyloid Β ◽  
Precursor Protein ◽  
Amyloid Β Peptide ◽  
Β Amyloid ◽  
Glycosphingolipid Biosynthesis
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