scholarly journals One pot synthesis of amine-functionalized and angular-shaped superparamagnetic iron oxide nanoparticles for MR/fluorescence bimodal imaging application

RSC Advances ◽  
2017 ◽  
Vol 7 (21) ◽  
pp. 12876-12885 ◽  
Author(s):  
Donggeon Yoo ◽  
Chaedong Lee ◽  
Bokyung Seo ◽  
Yuanzhe Piao

Herein, we report the simple preparation of water dispersible angular-shaped amine-functionalized super-paramagnetic iron oxide nanoparticles (A-SPIONs).

2019 ◽  
Vol 290 ◽  
pp. 301-306
Author(s):  
Osama Abu Noqta ◽  
Azlan Abdul Aziz ◽  
Adamu Ibrahim Usman

Superparamagnetic iron oxide nanoparticles (SPION) were synthesized by one pot coprecipitation method at room temperature in the presence of Polyvinylpyrrolidone (PVP). X-ray powder diffraction (XRD), transmission electron microscopy (TEM), and Vibrating Sample Magnetometer (VSM) were used to analysis the physicochemical properties of PVP-SPION. The XRD patterns confirmed that the structure of as-synthesized sample is magnetite with cubic structure system. In TEM results, the image of PVP-SPION displayed that the size of particles was 14.05 nm with narrower size distribution and also the PVP played important role to minimize the agglomeration of SPION. Finally, the high saturation magnetization value of PVP-SPION (53.0 emu/g) indicate the as-synthesized sample has a great potential as a contrast agent for MRI.


RSC Advances ◽  
2016 ◽  
Vol 6 (102) ◽  
pp. 99948-99959 ◽  
Author(s):  
Ganeshlenin Kandasamy ◽  
Sreeraj Surendran ◽  
Anindita Chakrabarty ◽  
S. N. Kale ◽  
Dipak Maity

We report a one-step facile synthesis of novel water-soluble and functionalized SPIONs, which could be promising candidates for cancer theranostics.


2010 ◽  
Vol 3 (2) ◽  
pp. 161-167 ◽  
Author(s):  
Anuj Shukla ◽  
Manoj Kumar Patra ◽  
Manoth Mathew ◽  
Sandhya Songara ◽  
Vivek Kumar Singh ◽  
...  

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Thomas Girardet ◽  
Amel Cherraj ◽  
Astrid Pinzano ◽  
Christel Henrionnet ◽  
Franck Cleymand ◽  
...  

Abstract Superparamagnetic Iron Oxide Nanoparticles (SPIONs) are widely used in various areas of the biomedical field: for diagnosis (Magnetic Resonance Imaging), for therapeutic applications (hyperthermia, nanovectorization). These applications require a good stability in water and no aggregation of SPIONs, with well-controlled physicochemical and magnetic properties. In this work, SPIONs functionalized by citrate ligands are synthesized in a one-step process with the aim of producing stable water-dispersible nanoparticles with a well-crystallized spinel structure. Microwave technology is implemented to achieve this objective given the ease, speed and reproducibility of the method. For their future use in biomedical applications, the sterilization of these SPIONs are essential by an autoclave treatment. The influence of this treatment on the physicochemical and magnetic properties of the SPIONs is determined by a systematic characterization before and after sterilization by Transmission Electronic Microscopy, Dynamic Light Scattering, X-ray Diffraction, Fourier Transformed Infra-Red, ThermoGravimetric Analysis and magnetic measurements.


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