scholarly journals Thermoplastic microfluidic devices for targeted chemical and biological applications

RSC Advances ◽  
2017 ◽  
Vol 7 (5) ◽  
pp. 2884-2889 ◽  
Author(s):  
Dan Voicu ◽  
Gabriella Lestari ◽  
Yihe Wang ◽  
Michael DeBono ◽  
Minseok Seo ◽  
...  
Keyword(s):  
Microfluidic Devices ◽  
Hot Embossing ◽  
High Fidelity ◽  
Biological Applications ◽  
Cost Efficient

Photolithography and hot embossing offers the capability of cost-efficient and high-fidelity fabrication of polymer microfluidic devices.

scholarly journals High fidelity, high yield production of microfluidic devices by hot embossing lithography: rheology and stiction

Lab on a Chip ◽  
2006 ◽  
Vol 6 (7) ◽  
pp. 936 ◽  
Author(s):  
Neil S. Cameron ◽  
Helene Roberge ◽  
Teodor Veres ◽  
Stephen C. Jakeway ◽  
H. John Crabtree
Keyword(s):  
Microfluidic Devices ◽  
Hot Embossing ◽  
High Yield ◽  
High Fidelity ◽  
Yield Production ◽  
High Yield Production

REPLICATION OF NANO/MICRO QUARTZ MOLD BY HOT EMBOSSING AND ITS APPLICATION TO BOROSILICATE GLASS EMBOSSING

2008 ◽  
Vol 22 (31n32) ◽  
pp. 6118-6123 ◽  
Author(s):  
SUNG-WON YOUN ◽  
CHIEKO OKUYAMA ◽  
MASHARU TAKAHASHI ◽  
RYUTARO MAEDA
Keyword(s):  
High Performance ◽  
Focused Ion Beam ◽  
Ion Beam ◽  
Hot Embossing ◽  
High Fidelity ◽  
Borosilicate Glasses ◽  
Mems Devices ◽  
Barrier Layers ◽  
Multiple Copies ◽  
Micro Electromechanical System

Glass hot-embossing is one of essential techniques for the development of high-performance optical, bio, and chemical micro electromechanical system (MEMS) devices. This method is convenient, does not require routine access to clean rooms and photolithographic equipment, and can be used to produce multiple copies of a quartz mold as well as a MEMS component. In this study, quartz molds were prepared by hot-embossing with the glassy carbon (GC) masters, and they were applied to the hot-emboss of borosilicate glasses. The GC masters were prepared by dicing and focused ion beam (FIB) milling techniques. Additionally, the surfaces of the embossed quartz molds were coated with molybdenum barrier layers before embossing borosilicate glasses. As a result, micro-hot-embossed structures could be developed in borosilicate glasses with high fidelity by hot embossing with quartz molds.

Cyclic olefin copolymer as an X-ray compatible material for microfluidic devices

Lab on a Chip ◽  
2018 ◽  
Vol 18 (1) ◽  
pp. 171-178 ◽  
Author(s):  
Manuela Denz ◽  
Gerrit Brehm ◽  
Clément Y. J. Hémonnot ◽  
Heidi Spears ◽  
Andrew Wittmeier ◽  
...  
Keyword(s):  
Small Angle ◽  
Microfluidic Devices ◽  
Hot Embossing ◽  
Cyclic Olefin Copolymer ◽  
Cyclic Olefin ◽  
X Ray ◽  
X Ray Scattering ◽  
Ray Scattering

Fabrication of X-ray compatible microfluidic devices by hot embossing, and characterization for small angle X-ray scattering.

Fabrication of a Flexible Metal/Polymer Mold With Liquid Crystal Polymer Material for Hot-Embossing Process

2010 ◽  
Author(s):  
Haijing Lu ◽  
Xiao Fang Ang ◽  
Hongping Liu ◽  
Zheng Sun ◽  
Jun Wei
Keyword(s):  
Smooth Surface ◽  
Low Cost ◽  
Hot Embossing ◽  
High Fidelity ◽  
Thermoplastic Polymer ◽  
Flexible Polymer ◽  
Crystal Polymer ◽  
Flexible Metal ◽  
Polymer Mold ◽  
Metal Polymer

A flexible polymer is considered as an alternative of low-cost mold materials. Molds with a high density aspect ratio, smooth surface, vertical sidewalls and lightweight have been fabricated and it is easy-to-use features in the hot embossing process. The study also indicated that the flexible metal/polymer mold could be used for thermoplastic polymer patterning with high fidelity and low cost. Using the flexible metal/polymer mold, 10um and 5um structures were fabricated.

scholarly journals 3D printed metal molds for hot embossing plastic microfluidic devices

Lab on a Chip ◽  
2017 ◽  
Vol 17 (2) ◽  
pp. 241-247 ◽  
Author(s):  
Tung-Yi Lin ◽  
Truong Do ◽  
Patrick Kwon ◽  
Peter B. Lillehoj
Keyword(s):  
Microfluidic Devices ◽  
Hot Embossing ◽  
Unique Approach ◽  
3D Printed

We demonstrate a unique approach for fabricating plastic microfluidic devices via hot embossing using 3D printed metal molds.

Avoiding Thiol Compound Interference: A Nanoplatform Based on High-Fidelity Au-Se Bonds for Biological Applications

2018 ◽  
Vol 130 (19) ◽  
pp. 5404-5407 ◽  
Author(s):  
Bo Hu ◽  
Fanpeng Kong ◽  
Xiaonan Gao ◽  
Lulu Jiang ◽  
Xiaofeng Li ◽  
...  
Keyword(s):  
High Fidelity ◽  
Biological Applications ◽  
Thiol Compound

Microfabrication (Hot-Embossing) of COC Microfluidic Devices: Effect of Norbornene Content on Replication Fidelity and Surface Modification by UV-Photografting

2013 ◽  
Vol 543 ◽  
pp. 51-54
Author(s):  
Rajeeb Kumar Jena ◽  
Chee Yoon Yue
Keyword(s):  
Surface Modification ◽  
Microfluidic Devices ◽  
Processing Parameters ◽  
Hot Embossing ◽  
Contact Angle Measurement ◽  
Angle Measurement ◽  
Experimental Conditions ◽  
Water Contact ◽  
Replication Fidelity ◽  
Modified Surface

The fabrication of polymer based microfluidic devices using the hot embossing technique and their surface modification for easy fluid flow through the devices has been a growing field of research. During hot embossing, the replication fidelity on polymer substrate not only depends on the processing parameters such as temperature, pressure and time but also on their chemical structure which affects their thermo-dependent viscoelastic properties. For copolymers such as cyclic olefin copolymer (COC) which comprises ethylene and norbornene units, such properties depend on their relative ethylene and norbornene content. We report in this paper, a systematic study of replication fidelity and surface modification on COC polymer with varying norbornene content from 65 to 82 wt%. Replication fidelity which includes the surface morphology and cross-section profiles of the microchannel were characterized using SEM and Confocal microscope respectively. The modified surface was evaluated using Fourier transform infrared spectroscopy (FTIR spectroscopy) and water contact angle measurement. It was observed that in hot embossing, higher norbornene content contributed to good replication fidelity at identical experimental conditions. Furthermore, it was observed that with increase in norbornene content, the grafting efficiency decreases resulting in poor surface modification.

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