scholarly journals Probing the binding behavior and kinetics of silver nanoparticles with bovine serum albumin

RSC Advances ◽  
2017 ◽  
Vol 7 (15) ◽  
pp. 9393-9401 ◽  
Author(s):  
Gongke Wang ◽  
Yanfang Lu ◽  
Huimin Hou ◽  
Yufang Liu
Keyword(s):  
Silver Nanoparticles ◽  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Bovine Serum ◽  
Binding Behavior ◽  
Kinetics Of

The binding of BSA to AgNPs will open a door to fully understand the essence of the interactions between nanoparticles and proteins.

Biodistribution and long-term fate of silver nanoparticles functionalized with bovine serum albumin in rats

Metallomics ◽  
2010 ◽  
Vol 2 (3) ◽  
pp. 204-210 ◽  
Author(s):  
Lourdes Garza-Ocañas ◽  
Domingo A. Ferrer ◽  
Justin Burt ◽  
Luis A. Diaz-Torres ◽  
Mónica Ramírez Cabrera ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Bovine Serum

Green synthesis of silver nanoparticles from Delonix regia leaf extracts: In-vitro cytotoxicity and interaction studies with bovine serum albumin

2020 ◽  
Vol 242 ◽  
pp. 122493 ◽  
Author(s):  
Md Abrar Siddiquee ◽  
Mehraj ud din Parray ◽  
Syed Hassan Mehdi ◽  
Khalid Ahmed Alzahrani ◽  
Abdulmohsen Ali Alshehri ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Green Synthesis ◽  
Bovine Serum ◽  
In Vitro Cytotoxicity ◽  
Leaf Extracts ◽  
Delonix Regia ◽  
Interaction Studies

scholarly journals Insight into the Molecular Interaction of Cloxyquin (5-chloro-8-hydroxyquinoline) with Bovine Serum Albumin: Biophysical Analysis and Computational Simulation

2019 ◽  
Vol 21 (1) ◽  
pp. 249 ◽  
Author(s):  
Kamonrat Phopin ◽  
Waralee Ruankham ◽  
Supaluk Prachayasittikul ◽  
Virapong Prachayasittikul ◽  
Tanawut Tantimongcolwat
Keyword(s):  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Hydrophobic Interaction ◽  
Bovine Serum ◽  
Computational Simulation ◽  
Docking Simulation ◽  
Biophysical Model ◽  
Therapeutic Drug ◽  
Fatty Acid Binding ◽  
Binding Behavior

Cloxyquin is a potential therapeutic compound possessing various bioactivities, especially antibacterial, antifungal, cardioprotective, and pain relief activities. Herein, the interaction mechanism between cloxyquin and bovine serum albumin (BSA) has been elucidated in order to fulfill its pharmacokinetic and pharmacodynamic gaps essential for further development as a therapeutic drug. Multi-spectroscopic and biophysical model analysis suggested that cloxyquin interacts with BSA via a static process by ground-state complex formation. Its binding behavior emerged as a biphasic fashion with a moderate binding constant at the level of 104 M−1. Thermodynamic analysis and molecular docking simulation concurrently revealed that hydrophobic interaction is a major driving force for BSA–cloxyquin complexation. Binding of cloxyquin tends to slightly enlarge the monomeric size of BSA without a significant increase of aggregate fraction. Cloxyquin preferentially binds into the fatty acid binding site 5 (FA5) of the BSA via hydrophobic interaction amongst its quinoline scaffold and Phe550, Leu531, and Leu574 residues of BSA. The quinoline ring and hydroxyl moiety of cloxyquin also form the π–π interaction and the hydrogen bond with Phe506. Our data indicate a potential function of serum albumin as a carrier of cloxyquin in blood circulation.

Aggregation kinetics of bovine serum albumin studied by FTIR spectroscopy and light scattering

2004 ◽  
Vol 107 (2) ◽  
pp. 175-187 ◽  
Author(s):  
Valeria Militello ◽  
Carlo Casarino ◽  
Antonio Emanuele ◽  
Antonella Giostra ◽  
Filippo Pullara ◽  
...  
Keyword(s):  
Light Scattering ◽  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Ftir Spectroscopy ◽  
Bovine Serum ◽  
Aggregation Kinetics ◽  
Kinetics Of

scholarly journals Kinetics of Glycoxidation of Bovine Serum Albumin by Methylglyoxal and Glyoxal and its Prevention by Various Compounds

Molecules ◽  
2014 ◽  
Vol 19 (4) ◽  
pp. 4880-4896 ◽  
Author(s):  
Izabela Sadowska-Bartosz ◽  
Sabina Galiniak ◽  
Grzegorz Bartosz
Keyword(s):  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Bovine Serum ◽  
Kinetics Of
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