scholarly journals Development and characterization of heparin-immobilized polycaprolactone nanofibrous scaffolds for tissue engineering using gamma-irradiation

RSC Advances ◽  
2017 ◽  
Vol 7 (15) ◽  
pp. 8963-8972 ◽  
Author(s):  
Jin-Oh Jeong ◽  
Sung In Jeong ◽  
Jong-Seok Park ◽  
Hui-Jeong Gwon ◽  
Sung-Jun Ahn ◽  
...  

Polycaprolactone (PCL) has been considered a useful material for orthopedic devices and osseous implants because of its biocompatibility and bone-forming activity.

2014 ◽  
Vol 55 (4) ◽  
pp. 907-916 ◽  
Author(s):  
Caihong Lei ◽  
Hailin Zhu ◽  
Jingjing Li ◽  
Jiuming Li ◽  
Xinxing Feng ◽  
...  

2011 ◽  
Vol 284-286 ◽  
pp. 459-463 ◽  
Author(s):  
Yuan Yuan Qi ◽  
Bin Liu ◽  
Xing Bin Yan

Nanofibrous scaffolds of PVA and HA were prepared by electrospinning. SEM showed the scaffolds had porous nanofibrous morphology, and the diameter of the fibers was in the range of 200-1000 nm. FTIR and XRD showed the presence of HA in the scaffolds. The mechanical properties of the scaffolds changed by the adding content of HA. For the nanoscaffolds with 2wt % HA, the ultimate tensile strength and the elongation at break was 7.5 MPa and 17%. The PVA/HA nanoscaffolds prepared by electrospinning indicated good properties, and had a potential applications in bone tissue engineering and drug delivery systems.


Author(s):  
Touseef Amna ◽  
M. Shamshi Haasan ◽  
Myung-Seob Khil ◽  
Inho Hwang

Nanotextured materials or nanomaterials offer diverse remarkable applications in various walks of life owing to their unique geometry. This chapter is focused on the synthesis and characterization of electrospun nanofibrous matrices as a novel biomimetic scaffold for the cultivation of cells and tissues; in particular muscle cells and tissues. Tissue engineering is exceedingly interdisciplinary branch of science which integrates the benefits of life sciences and medicine with those of engineering. In order to cultivate muscle cells in-vitro, it is necessary to have a 3D scaffold. In tissue engineering applications or even in 3D cell cultures, the biological cross talk between cells and the scaffold is controlled by the material properties and scaffold characteristics. This chapter provides a general overview of the common approaches and techniques used for designing nanofibrous scaffolds for culture of cells specifically muscle cells. The limitations and benefits of the tissue engineering are discussed.


2017 ◽  
Vol 67 (1) ◽  
pp. 27-35 ◽  
Author(s):  
Shiva Rahmani ◽  
Fatemeh Tabandeh ◽  
Shahab Faghihi ◽  
Ghassem Amoabediny ◽  
Mehdi Shakibaie ◽  
...  

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