Fabrication and characterization of bioactive glass/alginate composite scaffolds by a self-crosslinking processing for bone regeneration

RSC Advances ◽  
2016 ◽  
Vol 6 (94) ◽  
pp. 91201-91208 ◽  
Author(s):  
Fujian Zhao ◽  
Wen Zhang ◽  
Xiaoling Fu ◽  
Weihan Xie ◽  
Xiaofeng Chen
Keyword(s):  
Bioactive Glass ◽  
Bone Regeneration ◽  
Glass Microspheres ◽  
Composite Scaffolds ◽  
Crosslinking Process ◽  
Fabrication And Characterization

Bioactive glass/alginate composite scaffolds were fabricated through a self-crosslinking process by bioactive glass microspheres provided Ca2+completely.

scholarly journals Fabrication and in vitro characterization of bioactive glass composite scaffolds for bone regeneration

2013 ◽  
Vol 5 (4) ◽  
pp. 045005 ◽  
Author(s):  
Patrina S P Poh ◽  
Dietmar W Hutmacher ◽  
Molly M Stevens ◽  
Maria A Woodruff
Keyword(s):  
Bioactive Glass ◽  
Bone Regeneration ◽  
Glass Composite ◽  
Composite Scaffolds ◽  
In Vitro Characterization

scholarly journals Fabrication and characterization of 45S5 bioactive glass microspheres

2020 ◽  
Author(s):  
Nursyazwani Ismail ◽  
Hasmaliza Mohamad ◽  
Nurazreena Ahmad
Keyword(s):  
Bioactive Glass ◽  
Glass Microspheres ◽  
Fabrication And Characterization

scholarly journals Fabrication and Characterization of Ta–GelMA–BG Scaffolds by Chemical Crosslinking Processing for Promotion Osteointegration

2021 ◽  
Vol 8 ◽  
Author(s):  
Fujian Zhao ◽  
Xiongfa Ji ◽  
Yang Yan ◽  
Zhen Yang ◽  
Xiaofeng Chen ◽  
...  
Keyword(s):  
Early Stage ◽  
Bone Defects ◽  
Chemical Crosslinking ◽  
Composite Scaffolds ◽  
Load Bearing ◽  
3D Printed ◽  
Fabrication And Characterization ◽  
Cell Adhesion And Proliferation

The repair of bone defects in load-bearing positions still faces great challenges. Tantalum (Ta) has attempted to repair bone defects based on the excellent mechanical properties. However, the osseointegration of Ta needs to be improved due to the lack of osteoinduction. Herein, tantalum–gelatin–methacryloyl–bioactive glass (Ta–GelMA–BG) scaffolds were successfully fabricated by loading BG in 3D-printed Ta scaffolds through a chemical crosslinking method. The results showed that the composite scaffolds have the ability to promote cell adhesion and proliferation. The incorporation of BG resulted in a significant increase in apatite-forming and osteogenesis differentiation abilities. In vivo results indicated that the Ta–GelMA–BG scaffolds significantly enhanced the osteointegration at the early stage after implantation. Overall, the Ta–GelMA–BG scaffolds are a promising platform for the load bearing bone regeneration field.

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