Dihydropyridine-based fluorescence probe for nitric oxide

RSC Advances ◽  
2016 ◽  
Vol 6 (89) ◽  
pp. 85698-85703 ◽  
Author(s):  
Su-Fang Ma ◽  
Qiu-Hua Wang ◽  
Fu-Tao Liu ◽  
Hui-Li Wang ◽  
De-Cai Fang ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Cell Imaging ◽  
High Selectivity ◽  
Fluorescence Probe

A fluorescence probe for detecting nitric oxide based on dihydropyridine showed high selectivity and sensitivity as well as cell imaging ability.

scholarly journals Nile-Red-Based Fluorescence Probe for Selective Detection of Biothiols, Computational Study, and Application in Cell Imaging

Molecules ◽  
2020 ◽  
Vol 25 (20) ◽  
pp. 4718
Author(s):  
Xiang Rong ◽  
Zhong-Yong Xu ◽  
Jin-Wu Yan ◽  
Zhi-Zhong Meng ◽  
Bin Zhu ◽  
...  
Keyword(s):  
Cell Imaging ◽  
High Selectivity ◽  
Fluorescence Enhancement ◽  
Fluorescence Probe ◽  
Color Change ◽  
Computational Study ◽  
Theoretical Calculations ◽  
Nile Red ◽  
Blue Shift ◽  
Selective Detection

A new colorimetric and fluorescence probe NRSH based on Nile-red chromophore for the detection of biothiols has been developed, exhibiting high selectivity towards biothiols over other interfering species. NRSH shows a blue shift in absorption peak upon reacting with biothiols, from 587 nm to 567 nm, which induces an obvious color change from blue to pink and exhibits a 35-fold fluorescence enhancement at 645 nm in red emission range. NRSH displays rapid (<1 min) response for H2S, which is faster than other biothiols (>5 min). The detection limits of probe NRSH towards biothiols are very low (22.05 nM for H2S, 34.04 nM for Cys, 107.28 nM for GSH and 113.65 nM for Hcy). Furthermore, NRSH is low cytotoxic and can be successfully applied as a bioimaging tool for real-time monitoring biothiols in HeLa cells. In addition, fluorescence mechanism of probe NRSH is further understood by theoretical calculations.

Dansyl-appended CuII-complex-based nitroxyl (HNO) sensing with living cell imaging application and DFT studies

2019 ◽  
Vol 48 (8) ◽  
pp. 2760-2771 ◽  
Author(s):  
Debjani Maiti ◽  
Abu Saleh Musha Islam ◽  
Ananya Dutta ◽  
Mihir Sasmal ◽  
Chandraday Prodhan ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Copper Complex ◽  
Cell Imaging ◽  
High Selectivity ◽  
Dft Studies ◽  
Sulfur Species ◽  
Turn On ◽  
Imaging Application ◽  
Fluorescence Turn On ◽  
Living Cell Imaging

We introduce herein, a novel copper complex-based fluorescent probe[CuII(DQ468)Cl]+that exhibits a significant fluorescence turn-on response towards nitroxyl with high selectivity over other biological reactive oxygen, nitrogen and sulfur species, including nitric oxide.

scholarly journals A Highly Selective Turn-On Fluorescent Probe for the Detection of Zinc

Molecules ◽  
2021 ◽  
Vol 26 (13) ◽  
pp. 3825
Author(s):  
Ling-Yi Shen ◽  
Xiao-Li Chen ◽  
Xian-Jiong Yang ◽  
Hong Xu ◽  
Ya-Li Huang ◽  
...  
Keyword(s):  
High Selectivity ◽  
Fluorescence Probe ◽  
Stoichiometric Ratio ◽  
X Ray Diffraction ◽  
X Ray ◽  
Turn On ◽  
Imine Nitrogen ◽  
System A ◽  
Plot Analysis ◽  
L System

A novel turn-on fluorescence probe L has been designed that exhibits high selectivity and sensitivity with a detection limit of 9.53 × 10−8 mol/L for the quantification of Zn2+. 1H-NMR spectroscopy and single crystal X-ray diffraction analysis revealed the unsymmetrical nature of the structure of the Schiff base probe L. An emission titration experiment in the presence of different molar fractions of Zn2+ was used to perform a Job’s plot analysis. The results showed that the stoichiometric ratio of the complex formed by L and Zn2+ was 1:1. Moreover, the molecular structure of the mononuclear Cu complex reveals one ligand L coordinates with one Cu atom in the asymmetric unit. On adding CuCl2 to the ZnCl2/L system, a Cu-Zn complex was formed and a strong quenching behavior was observed, which inferred that the Cu2+ displaced Zn2+ to coordinate with the imine nitrogen atoms and hydroxyl oxygen atoms of probe L.

scholarly journals A highly selective ratiometric fluorescent probe for the cascade detection of Zn2+ and H2PO4− and its application in living cell imaging

RSC Advances ◽  
2017 ◽  
Vol 7 (64) ◽  
pp. 40615-40620 ◽  
Author(s):  
Kui Du ◽  
Shizhen Niu ◽  
Li Qiao ◽  
Yandong Dou ◽  
Qing Zhu ◽  
...  
Keyword(s):  
Charge Transfer ◽  
Fluorescent Probe ◽  
Living Cell ◽  
Cell Imaging ◽  
High Selectivity ◽  
Ratiometric Sensor ◽  
Intermolecular Charge Transfer ◽  
Living Cell Imaging ◽  
Ratiometric Fluorescent Probe

A simple ratiometric sensor (L1) for the cascade detection of Zn2+ and H2PO4− with high selectivity was reported based on the intermolecular charge transfer (ICT) mechanism.

scholarly journals Correction: A smart molecular probe for selective recognition of nitric oxide in 100% aqueous solution with cell imaging application and DFT studies

2019 ◽  
Vol 17 (10) ◽  
pp. 2825-2825 ◽  
Author(s):  
Ananya Dutta ◽  
Abu Saleh Musha Islam ◽  
Debjani Maiti ◽  
Mihir Sasmal ◽  
Chandraday Prodhan ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Aqueous Solution ◽  
Cell Imaging ◽  
Molecular Probe ◽  
Selective Recognition ◽  
Dft Studies ◽  
Imaging Application

Correction for ‘A smart molecular probe for selective recognition of nitric oxide in 100% aqueous solution with cell imaging application and DFT studies’ by Ananya Dutta et al., Org. Biomol. Chem., 2019, DOI: 10.1039/c9ob00177h.

scholarly journals A highly selective fluorescent probe for the sensing of Cu2+ based on the hydrolysis of a quinoline-2-carboxylate and its application in cell imaging

2020 ◽  
pp. 174751982097392
Author(s):  
Qihua You ◽  
Yihua Zhuo ◽  
Yadong Feng ◽  
Yujuan Xiao ◽  
Yanyu Zhang ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Cell Imaging ◽  
High Selectivity ◽  
Living Cells ◽  
World Health ◽  
Strong Fluorescence ◽  
The World ◽  
Phenolic Group ◽  
Health Organization ◽  
Hydrolysis Of

A highly selective OFF–ON fluorescent probe is developed for the sensing of Cu2+ based on the hydrolysis of a quinoline-2-carboxylate moiety. The probe is weakly fluorescent due to esterification of the phenolic group. Upon treatment with 1 equiv. of Cu2+, the probe exhibits strong fluorescence at 570 nm. The probe also exhibits high selectivity for Cu2+ over other cations with a low detection limit of 0.2 μM, which is sensitive enough to meet the standard of the World Health Organization for Cu2+ in drinking water (30 μM). Moreover, the probe shows a very low cell cytotoxicity, and imaging experiments demonstrate that the probe can be used for the sensing of Cu2+ in living cells.

A turn-on near-infrared fluorescence probe with aggregation-induced emission based on dibenzo[a,c]phenazine for detection of superoxide anions and its application in cell imaging

The Analyst ◽  
2018 ◽  
Vol 143 (5) ◽  
pp. 1242-1249 ◽  
Author(s):  
Ji Yang ◽  
Xianglong Liu ◽  
Honglei Wang ◽  
Haoqi Tan ◽  
Xiaoxu Xie ◽  
...  
Keyword(s):  
Superoxide Anion ◽  
Near Infrared ◽  
Cell Imaging ◽  
Fluorescence Probe ◽  
Stokes Shift ◽  
Superoxide Anions ◽  
Near Infrared Fluorescence ◽  
Anion Detection ◽  
Aggregation Induced Emission ◽  
Turn On

A new turn-on near-infrared fluorescence probe (BDP) based on dibenzo[a,c]phenazine for superoxide anion detection with AIE properties and a large Stokes shift was developed.

A novel rhodamine-based fluorescent probe for selective detection of ClO– and its application in living cell imaging

2018 ◽  
Vol 96 (12) ◽  
pp. 1129-1133
Author(s):  
Changping Yang ◽  
Mingliang Zuo ◽  
Xiaoli Hu ◽  
Xuelin Chen ◽  
Duoduo Zhang ◽  
...  
Keyword(s):  
Aqueous Solution ◽  
Cell Imaging ◽  
High Selectivity ◽  
Fluorescence Enhancement ◽  
Colour Change ◽  
Living Cells ◽  
Fluorescent Imaging ◽  
Selective Detection ◽  
Living Cell Imaging ◽  
Interfering Ions

A novel fluorescent rhodamine-based probe L for selective responding to ClO– has been synthesized and characterized. The spectroscopy showed that probe L can detect ClO– in aqueous solution without interaction with other interfering ions, and the detection is also evident by the colour change from colourless to reddish purple under white light. The remarkable fluorescence enhancement showed the high selectivity and sensitivity of probe L for the detection of ClO–. Furthermore, probe L was applied to intracellular fluorescent imaging of HeLa cells treated with ClO– and MTT assay showed nontoxicity in living cells.

A novel ratiometric fluorescence probe for hypochlorite detection and its application in cell imaging

2020 ◽  
Vol 1221 ◽  
pp. 128812 ◽  
Author(s):  
Zhiwei Ma ◽  
Xiaopei Chen ◽  
Chuanchuan Wang ◽  
Quanjian Lv
Keyword(s):  
Cell Imaging ◽  
Fluorescence Probe ◽  
Ratiometric Fluorescence
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