New chloramphenicol Schiff base ligands for the titanium-mediated asymmetric aldol reaction of α,β-unsaturated aldehydes with diketene: a short synthesis of atorvastatin calcium

RSC Advances ◽  
2016 ◽  
Vol 6 (79) ◽  
pp. 75470-75477 ◽  
Author(s):  
Haifeng Wang ◽  
Linjie Yan ◽  
Fangjun Xiong ◽  
Yan Wu ◽  
Fener Chen
Keyword(s):  
Schiff Base ◽  
Aldol Reaction ◽  
Schiff Base Ligands ◽  
Asymmetric Aldol ◽  
Atorvastatin Calcium ◽  
Unsaturated Aldehydes ◽  
Asymmetric Aldol Reaction ◽  
Chiral Schiff Base ◽  
Short Synthesis

Several novel chiral Schiff base ligands were prepared from a commercially available chloramphenicol base and applied to the titanium-mediated asymmetric aldol reaction of diketene with various α,β-unsaturated aldehydes.

ChemInform Abstract: Asymmetric Aldol Reaction of Dichloroacetaldehyde Catalyzed by Diarylprolinol.

ChemInform ◽  
2016 ◽  
Vol 47 (49) ◽  
Author(s):  
Yujiro Hayashi ◽  
Daichi Nakamura ◽  
Yusuke Yasui ◽  
Kotaro Iwasaki ◽  
Hiroaki Chiba
Keyword(s):  
Aldol Reaction ◽  
Asymmetric Aldol ◽  
Asymmetric Aldol Reaction
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