Full vs. partial competitive binding behaviour in molecularly imprinted polymers. The case for a chlorinated phenoxyacids-binding polymer

RSC Advances ◽  
2016 ◽  
Vol 6 (82) ◽  
pp. 78317-78321
Author(s):  
G. Spano ◽  
C. Giovannoli ◽  
F. Di Nardo ◽  
L. Anfossi ◽  
C. Baggiani
Keyword(s):  
Molecularly Imprinted Polymers ◽  
Competitive Binding ◽  
Molecularly Imprinted ◽  
Imprinted Polymers ◽  
Binding Behaviour

The parameters governing the binding of a MIP towards a ligand are not conditioned by the presence of other competitors.

Synthesis and Evaluation of a Molecularly Imprinted Polymer Selective to 2,4,6-Trichlorophenol

2004 ◽  
Vol 57 (8) ◽  
pp. 759 ◽  
Author(s):  
Lachlan Schwarz ◽  
Clovia I. Holdsworth ◽  
Adam McCluskey ◽  
Michael C. Bowyer
Keyword(s):  
Molecularly Imprinted Polymer ◽  
Molecularly Imprinted Polymers ◽  
Competitive Binding ◽  
Imprinted Polymer ◽  
Binding Studies ◽  
Molecularly Imprinted ◽  
Imprinted Polymers ◽  
Target Molecule ◽  
High Preference ◽  
Structural Analogues

Molecularly imprinted polymers (MIPs) selective for the phenolic contaminant 2,4,6-trichlorophenol (2,4,6-TCP) were prepared and evaluated in three porogens of differing character (hexane, acetonitrile, dichloromethane). Rebinding of 2,4,6-TCP was found to be most effective in dichloromethane (imprinting factor: 13.2). Competitive binding studies performed against a range of close structural analogues showed a high preference for the target molecule, although partial recognition towards 2,4-dichlorophenol was also observed. Specificity was found to be dependent upon the presence of ring chlorine on the target, which suggested that these atoms participate in secondary binding interactions that are essential for successful recognition in the polymer cavity.

scholarly journals Synthesis of fluorescent drug molecules for competitive binding assay based on molecularly imprinted polymers

RSC Advances ◽  
2019 ◽  
Vol 9 (12) ◽  
pp. 6779-6784 ◽  
Author(s):  
Muyasier Wubulikasimu ◽  
Turghun Muhammad ◽  
Mukhtar Imerhasan ◽  
Nurmemet Hudaberdi ◽  
Wenwu Yang ◽  
...  
Keyword(s):  
Molecularly Imprinted Polymers ◽  
Binding Assay ◽  
Competitive Binding ◽  
Natural Antibody ◽  
Competitive Binding Assay ◽  
Molecularly Imprinted ◽  
Imprinted Polymers ◽  
Drug Molecules ◽  
Immunosorbent Assays

Drug molecules (metronidazole, zidovudine and lamivudine) were successfully labelled with a fluorescent reagent and used to develop fluorescent biomimetic immunosorbent assays using molecularly imprinted polymers in the place of natural antibody.

Binding behaviour of molecularly imprinted polymers prepared by a hierarchical approach in mesoporous silica beads of varying porosity

2011 ◽  
Vol 1218 (14) ◽  
pp. 1828-1834 ◽  
Author(s):  
Claudio Baggiani ◽  
Patrizia Baravalle ◽  
Cristina Giovannoli ◽  
Laura Anfossi ◽  
Cinzia Passini ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Molecularly Imprinted Polymers ◽  
Hierarchical Approach ◽  
Molecularly Imprinted ◽  
Imprinted Polymers ◽  
Silica Beads ◽  
Binding Behaviour

Preparation of Benzonic Acid Molecularly Imprinted Polymers and Its Adsorption Property

2010 ◽  
Vol 38 (3) ◽  
pp. 401-404
Author(s):  
Da-Wei LOU ◽  
Ying-Jie YANG ◽  
Guang HUANG ◽  
Ping-Li PU ◽  
Xin-Qing LEE ◽  
...  
Keyword(s):  
Molecularly Imprinted Polymers ◽  
Adsorption Property ◽  
Molecularly Imprinted ◽  
Imprinted Polymers

scholarly journals Adsorption Capacity and Selectivity of Molecularly Imprinted Polymers towards β-Sitosterol

2019 ◽  
Vol 31 (11) ◽  
pp. 2527-2531
Author(s):  
St. Fauziah ◽  
N.H. Soekamto ◽  
P. Budi ◽  
P. Taba
Keyword(s):  
Adsorption Capacity ◽  
Molecularly Imprinted Polymers ◽  
Solid Phase ◽  
Polymerization Reaction ◽  
Molecularly Imprinted ◽  
Imprinted Polymers ◽  
Sample Extract ◽  
Uv Visible ◽  
Adsorption Desorption ◽  
Isothermal Equation

Molecularly imprinted polymers (MIP) as an adsorbent has been synthesized using β-sitosterol as molecule template on free radical polymerization reaction. The capacity and selectivity of the adsorption from MIP to β-sitosterol was studied in this study. The β-sitosterol concentration in the adsorption-desorption test and the MIP selectivity test were analyzed by UV-visible and HPLC. The MIP obtained from the synthesis results in a high adsorption capacity. Based on the Freundlich adsorption isothermal equation, the adsorption capacity (k) was found to be 1.24 mg/g. The MIP can adsorb 100 % β-sitosterol while cholesterol was only 3 %. The MIP is most selective to β-sitosterol, therefore, has high potential to apply as adsorbent at solid phase extraction method to isolate β-sitosterol from sample extract.

Analytical Methods Incorporating Molecularly Imprinted Polymers (MIPs) for the Quantification of Microcystins: A Mini-Review

2021 ◽  
pp. 1-15
Author(s):  
P. U. Ashvin Iresh Fernando ◽  
Matthew W. Glasscott ◽  
Kaytee Pokrzywinski ◽  
Brianna M. Fernando ◽  
Gilbert K. Kosgei ◽  
...  
Keyword(s):  
Molecularly Imprinted Polymers ◽  
Analytical Methods ◽  
Molecularly Imprinted ◽  
Imprinted Polymers
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