Determination of p-aminohippuric acid with β-cyclodextrin sensitized fluorescence spectrometry

RSC Advances ◽  
2016 ◽  
Vol 6 (115) ◽  
pp. 114296-114303 ◽  
Author(s):  
Rashed H. Alremeithi ◽  
Mohammed A. Meetani ◽  
Mu'ath K. Mousa ◽  
Na'il I. Saleh ◽  
John Graham
Keyword(s):  
Fluorescence Detection ◽  
Plasma Flow ◽  
Renal Plasma Flow ◽  
Effective Renal Plasma Flow ◽  
Fluorescence Spectrometry ◽  
Detection Methods ◽  
Sensitized Fluorescence

Sensitive spectrofluorometric and HPLC with fluorescence detection methods have been developed for detection and determination of para-aminohippuric acid (a marker used for estimating effective renal plasma flow) in the presence of β-cyclodextrin.

Technetium-99mL,l-ethylenedicysteine clearance and correlation with iodine-125 orthoiodohippurate for the determination of effective renal plasma flow

1996 ◽  
Vol 23 (4) ◽  
pp. 365-370 ◽  
Author(s):  
Michel Stoffel ◽  
François Jamar ◽  
Chris Van Nerom ◽  
Alfons Verbruggen ◽  
Tatiana Besse ◽  
...  
Keyword(s):  
Plasma Flow ◽  
Renal Plasma Flow ◽  
Effective Renal Plasma Flow ◽  
Iodine 125

Comparison of 99Tcm-mercaptoacetyltriglycine and 131I-orthoiodohippurate in determination of effective renal plasma flow (ERPF)

1989 ◽  
Vol 10 (2) ◽  
pp. 99-108 ◽  
Author(s):  
HUSSEIN M. ABDEL-DAYEM ◽  
SAMY SADEK ◽  
RIAD AL-BAHAR ◽  
MOHAMMED SABHA ◽  
MOHAMMAD EL-SAYED
Keyword(s):  
Plasma Flow ◽  
Renal Plasma Flow ◽  
Effective Renal Plasma Flow

A Simplified Method for the Routine Determination of Effective Renal Plasma Flow

1986 ◽  
Vol 11 (11) ◽  
pp. 758-759
Author(s):  
JOHN L. FLOYD ◽  
DONALD E. JACKSON ◽  
JIM M. THOMAS
Keyword(s):  
Plasma Flow ◽  
Renal Plasma Flow ◽  
Effective Renal Plasma Flow ◽  
Simplified Method

A simplified method for the determination of effective renal plasma flow

1967 ◽  
Vol 15 (2) ◽  
pp. 219-231 ◽  
Author(s):  
L.W.Statius Van Eps ◽  
J. Geerling ◽  
M.E. Smorenberg-Schoorl ◽  
L.A. De Vries ◽  
A. Zurcher-Mulder
Keyword(s):  
Plasma Flow ◽  
Renal Plasma Flow ◽  
Effective Renal Plasma Flow ◽  
Simplified Method

EXTERNAL MONITORING AND PLASMA DISAPPEARANCE FOR THE DETERMINATION OF RENAL FUNCTION: COMPARISON OF EFFECTIVE RENAL PLASMA FLOW AND GLOMERULAR FILTRATION RATE

PEDIATRICS ◽  
1971 ◽  
Vol 48 (3) ◽  
pp. 377-392
Author(s):  
Melvin L. Cohen ◽  
Jivan K. Patel ◽  
David L. Baxter
Keyword(s):  
Glomerular Filtration ◽  
Plasma Flow ◽  
Single Injection ◽  
Renal Plasma Flow ◽  
Effective Renal Plasma Flow ◽  
External Monitoring ◽  
Disappearance Curve ◽  
Plasma Disappearance Curve ◽  
Small Scatter

In 40 patients effective renal plasma flow (ERPF) was measured by analyzing mathematically the plasma disappearance curve and the precordial external monitor disappearance curve of Na hippuran I131 simultaneously after a single injection of 30 µCu. The monitor curve is variably more shallow than the actual plasma curve. A mathematical interpolation is described using two plasma samples to correct the external monitor curve to approximate the entire plasma curve. ERPF determined by using the corrected monitor curve correlates well (r = .998) with the ERPF determined from the actual plasma curve and gives a small scatter (S.E. of estimate 11.1). The terminal exponential slope of plasma disappearance of Na hippuran I131 is apparent before 30 minutes and ERPF can then be obtained in a 40-minute study. Glomerular filtration rates (GFR) were performed in 34 patients using 10 µsCu of Na iothalamate I125, comparing values derived by blood and urine sampling with those derived by plasma disappearance. The latter method gave consistently falsely high values. The terminal exponential slope of the plasma disappearance curve for this isotope was not apparent before 80 or 90 minutes. Determination of GFR by plasma disappearance alone using Na iothalamate I125 is invalid in studies lasting up to 100 minutes after a single injection.

Comparative studies on the determination of the differential effective renal plasma flow with131I-hippuran and PAH

1973 ◽  
Vol 5 (2) ◽  
pp. 205-208
Author(s):  
D. Mushmov ◽  
M. Brailska ◽  
G. Budevski ◽  
L. Salambashev ◽  
Sl. Dimitrova
Keyword(s):  
Plasma Flow ◽  
Comparative Studies ◽  
Renal Plasma Flow ◽  
Effective Renal Plasma Flow

Clinical Renal Function Testing by External Double Isotope Monitoring Technique

1971 ◽  
Vol 10 (01) ◽  
pp. 16-24
Author(s):  
J. Fog Pedersen ◽  
M. Fog Pedersen ◽  
Paul Madsen
Keyword(s):  
Renal Function ◽  
Glomerular Filtration Rate ◽  
Glomerular Filtration ◽  
Plasma Flow ◽  
Filtration Rate ◽  
Renal Plasma Flow ◽  
Correlation Coefficients ◽  
Feedback System ◽  
Effective Renal Plasma Flow ◽  
Advantages And Disadvantages

SummaryAn accurate catheter-free technique for clinical determination simultaneouslyof glomerular filtration rate and effective renal plasma flow by means of radioisotopes has been developed. The renal function is estimated by the amount of radioisotopes necessary to maintain a constant concentration in the patient’s blood. The infusion pumps are steered by a feedback system, the pumps being automatically turned on when the radiation measured over the patient’s head falls below a certain preset level and turned off when this level is again readied. 131I-iodopyracet was used for the estimation of effective renal plasma flow and125I-iothalamate estimation of the glomerular filtration rate. These clearances were compared to the conventional bladder clearances and good correlation was found between these two clearance methods (correlation coefficients 0.97 and.90 respectively). The advantages and disadvantages of this new clearance technique are discussed.

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