Supramolecular prodrug micelles based on the complementary multiple hydrogen bonds as drug delivery platform for thrombosis therapy

RSC Advances ◽  
2016 ◽  
Vol 6 (67) ◽  
pp. 62478-62484 ◽  
Author(s):  
Wen'en Li ◽  
Haibo Wang ◽  
Zeliang Wei ◽  
Juewei Ning ◽  
Limei Ma ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Hydrogen Bonds ◽  
Ethylene Glycol ◽  
Poly Ethylene Glycol ◽  
Delivery Platform ◽  
Poly Ethylene ◽  
Multiple Hydrogen Bonds

To improve the effect of thrombosis therapy, an amphiphilic supramolecular prodrug consisting of diosgenin derivative (theophylline–diosgenin) and uracil-terminated poly(ethylene glycol) (PEG-U) was designed and synthesized successfully.

scholarly journals Bioreducible Micelles Self-Assembled from Poly(ethylene glycol)-Cholesteryl Conjugate As a Drug Delivery Platform

Polymers ◽  
2015 ◽  
Vol 7 (11) ◽  
pp. 2245-2258 ◽  
Author(s):  
Chulsu Baek ◽  
Tae-Lin Ha ◽  
Eunjoo Kim ◽  
Sang Jeong ◽  
Se Lee ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Ethylene Glycol ◽  
Poly Ethylene Glycol ◽  
Delivery Platform ◽  
Self Assembled ◽  
Poly Ethylene

Synthesis and self-assembly behaviour of poly(Nα-Boc-l-tryptophan)-block-poly(ethylene glycol)-block-poly(Nα-Boc-l-tryptophan)

RSC Advances ◽  
2016 ◽  
Vol 6 (29) ◽  
pp. 24142-24153
Author(s):  
Andreea S. Voda ◽  
Kevin Magniez ◽  
Nisa V. Salim ◽  
Cynthia Wong ◽  
Qipeng Guo
Keyword(s):  
Drug Delivery ◽  
Ethylene Glycol ◽  
Self Assembly ◽  
Triblock Copolymers ◽  
Potential Drug ◽  
Poly Ethylene Glycol ◽  
Drug Delivery Applications ◽  
Poly Ethylene ◽  
First Time

We report for the first time the use of Nα-Boc-l-tryptophan for the synthesis of amphiphilic BAB triblock copolymers for potential drug delivery applications.

Recent development of poly(ethylene glycol)-cholesterol conjugates as drug delivery systems

2014 ◽  
Vol 469 (1) ◽  
pp. 168-178 ◽  
Author(s):  
Zhi-Yao He ◽  
Bing-Yang Chu ◽  
Xia-Wei Wei ◽  
Jiao Li ◽  
Carl K. Edwards ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Ethylene Glycol ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene

Controlled Release of Proteins from Their Poly(Ethylene Glycol) Conjugates:  Drug Delivery Systems Employing 1,6-Elimination

2003 ◽  
Vol 14 (2) ◽  
pp. 395-403 ◽  
Author(s):  
Richard B. Greenwald ◽  
Karen Yang ◽  
Hong Zhao ◽  
Charles D. Conover ◽  
Stanford Lee ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Controlled Release ◽  
Ethylene Glycol ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene
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