Supported lipid bilayer membrane arrays on micro-patterned ITO electrodes

RSC Advances ◽  
2016 ◽  
Vol 6 (76) ◽  
pp. 72821-72826 ◽  
Author(s):  
Xuejing Wang ◽  
Ying Zhang ◽  
Hongmei Bi ◽  
Xiaojun Han

Lipid bilayer arrays were formed on micropatterned ITO electrodes. With this bilayer array platform both the fluorescence microscopy and electrochemical detection can be realized to explore the biophysical properties of cell membrane.

2013 ◽  
Vol 181 (1-2) ◽  
pp. 205-212 ◽  
Author(s):  
Peiyi Gao ◽  
Yunfeng Xia ◽  
Lele Yang ◽  
Tengfei Ma ◽  
Ling Yang ◽  
...  

Author(s):  
Zhihong Zhang ◽  
Wendong Ma ◽  
Kejie He ◽  
Bing Yuan ◽  
Kai Yang

Nanoparticles (NPs) promise a huge potential for clinically diagnostic and therapeutic applications. However, the nano-bio (e.g., the NP-cell membrane) interactions and underlying mechanisms are still largely elusive. In this work,...


Langmuir ◽  
1998 ◽  
Vol 14 (23) ◽  
pp. 6628-6631 ◽  
Author(s):  
James D. Burgess ◽  
Vivian W. Jones ◽  
Marc D. Porter ◽  
Melissa C. Rhoten ◽  
Fred M. Hawkridge

2018 ◽  
Vol 150 (11) ◽  
pp. 1472-1483 ◽  
Author(s):  
Janice L. Robertson

In 1918, the year the Journal of General Physiology was founded, there was little understanding of the structure of the cell membrane. It was evident that cells had invisible barriers separating the cytoplasm from the external solution. However, it would take decades before lipid bilayers were identified as the essential constituent of membranes. It would take even longer before it was accepted that there existed hydrophobic proteins that were embedded within the membrane and that these proteins were responsible for selective permeability in cells. With a combination of intuitive experiments and quantitative thinking, the last century of cell membrane research has led us to a molecular understanding of the structure of the membrane, as well as many of the proteins embedded within. Now, research is turning toward a physical understanding of the reactions of membrane proteins and lipids in this unique and incredibly complex solvent environment.


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