Photodynamic inactivation against Pseudomonas aeruginosa by curcumin microemulsions

RSC Advances ◽  
2016 ◽  
Vol 6 (67) ◽  
pp. 63013-63022 ◽  
Author(s):  
Chi-Hsien Liu ◽  
Wei-Shiou Lee ◽  
Wei-Chi Wu

Photodynamic inhibition of Pseudomonas aeruginosa is confirmed by curcumin microemulsion through the help of the blue light diode.

Author(s):  
Mariana Carreira Geralde ◽  
Thaila Quatrini Correa ◽  
Jose Dirceu Vollet-Filho ◽  
Cristina Kurachi ◽  
Vanderlei Salvador Bagnato ◽  
...  

Author(s):  
Eleonora Martegani ◽  
Fabrizio Bolognese ◽  
Nicola Trivellin ◽  
Viviana Teresa Orlandi

2009 ◽  
Vol 41 (5) ◽  
pp. 391-397 ◽  
Author(s):  
S.P. Tseng ◽  
L.J. Teng ◽  
C.T. Chen ◽  
T.H. Lo ◽  
W.C. Hung ◽  
...  

2015 ◽  
Vol 158 (4) ◽  
pp. 475-477 ◽  
Author(s):  
E. S. Keshishyan ◽  
Z. V. Zaporozhtseva ◽  
O. M. Zenina ◽  
V. S. Zrodnikov

2020 ◽  
Author(s):  
Artur Martynov ◽  
Boris Farber ◽  
Tatyana Osolodchenko ◽  
Ilya Klein

AbstractOne of the most promising methods for non-covalent inactivation of vaccine-producing microorganisms is the use of photoinactivation using riboflavin derivatives. The study used a dynamic combinatorial derivative of riboflavin - succinyl-maleinyl riboflavin. Corpuscular vaccines are divided into the following groups: from 2AB to 5AB - bacteria were inactivated by riboflavin derivative and blue light, and groups from 6AB to 9AB were inactivated by formalin (0.1% formalin in 9 log CFU was kept for 2 weeks in an thermostat and then sterility was determined - bacterial growth was not observed). A dynamic derivative of riboflavin at a final concentration of 0.02% can photo inactivate 6 time more bacteria P. Aeruginosa and E. coli than riboflavin. The minimum effective blue light emitter power (450 nm) for the photodynamic inactivation of both P. aeruginosa and E. coli is 1024.2 mW / cm2. In groups of mice pre-vaccinated intraperitoneally with corpuscular photo inactivated vaccines based on suspensions of and E. coli at doses of 0.5-1.0 ml 4 log (CFU) / mL, 100% survival of all animals was observed, whereas in control group with the same type of vaccines but formalin-treated vaccines, it failed to achieve a 100% protective effect.


Sign in / Sign up

Export Citation Format

Share Document