Biomimetic matrix mediated room temperature synthesis and characterization of nano-hydroxyapatite towards targeted drug delivery

RSC Advances ◽  
2016 ◽  
Vol 6 (67) ◽  
pp. 62556-62571 ◽  
Author(s):  
Lubna Sheikh ◽  
Sucheta Tripathy ◽  
Suprabha Nayar
Keyword(s):  
Drug Delivery ◽  
Targeted Drug Delivery ◽  
Room Temperature ◽  
Nucleation And Growth ◽  
Hydroxyapatite Nanoparticles ◽  
Delivery Vehicle ◽  
Temperature Synthesis ◽  
Targeted Drug ◽  
Potent Drug

Nucleation and growth of hydroxyapatite nanoparticles in the presence of different matrices acting as a potent drug delivery vehicle.

Exosomes separated based on the “STOP” criteria for tumor-targeted drug delivery

2018 ◽  
Vol 6 (18) ◽  
pp. 2758-2768 ◽  
Author(s):  
Hongzhao Qi ◽  
Lijun Yang ◽  
Xueping Li ◽  
Qi Zhan ◽  
Donglin Han ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Targeted Drug Delivery ◽  
Clinical Translation ◽  
Delivery Vehicle ◽  
Drug Delivery Vehicle ◽  
Related Drug ◽  
Targeted Drug

A new exosome-related drug delivery vehicle was explored based on the “STOP” criteria, dramatically promoting the clinical translation of exosomes.

Rhein-PEG-nHA conjugate as a bone targeted drug delivery vehicle for enhanced cancer chemoradiotherapy

2020 ◽  
Vol 27 ◽  
pp. 102196
Author(s):  
Xiuying Yang ◽  
Dongliang Zhai ◽  
Jia Song ◽  
Rui Qing ◽  
Bochu Wang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Targeted Drug Delivery ◽  
Delivery Vehicle ◽  
Drug Delivery Vehicle ◽  
Targeted Drug

scholarly journals Synthesis and characterization of a tumor-seeking LyP-1 peptide integrated lipid–polymer composite nanoparticle

2020 ◽  
Vol 1 (3) ◽  
pp. 469-480
Author(s):  
Ramesh Marasini ◽  
Tuyen Duong Thanh Nguyen ◽  
Sagar Rayamajhi ◽  
Santosh Aryal
Keyword(s):  
Drug Delivery ◽  
Polymer Composite ◽  
Targeted Drug Delivery ◽  
Synthesis And Characterization ◽  
Single Session ◽  
Biocompatible Polymer ◽  
Composite Nanoparticle ◽  
Targeted Drug

A simple and versatile nanoformulation strategy is presented by combining the synthetic lipids, biocompatible polymer, and tumor penetrating peptide (LyP-1) into a composite nanosystem for targeted drug delivery and imaging in a single session. 

scholarly journals Development and characterization of surface engineered PPI dendrimers for targeted drug delivery

2016 ◽  
Vol 45 (3) ◽  
pp. 414-425 ◽  
Author(s):  
Avleen Kaur ◽  
Keerti Jain ◽  
Neelesh Kumar Mehra ◽  
N. K. Jain
Keyword(s):  
Drug Delivery ◽  
Targeted Drug Delivery ◽  
Targeted Drug

Redox-responsive nanoreservoirs based on collagen end-capped mesoporous hydroxyapatite nanoparticles for targeted drug delivery

2014 ◽  
Vol 2 (36) ◽  
pp. 6089-6096 ◽  
Author(s):  
Dalong Li ◽  
Jinmei He ◽  
Weilu Cheng ◽  
Yadong Wu ◽  
Zhen Hu ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Targeted Drug Delivery ◽  
Hydroxyapatite Nanoparticles ◽  
Redox Responsive ◽  
Targeted Drug

Schematic illustration of a redox-responsive system based on collagen-capped MHAp for cell-targeted drug delivery.

Diselenium-containing ultrathin polymer nanocapsules for highly efficient targeted drug delivery and combined anticancer effect

2019 ◽  
Vol 7 (32) ◽  
pp. 4927-4932 ◽  
Author(s):  
Shuang Fu ◽  
Fei Li ◽  
Mingsong Zang ◽  
Zherui Zhang ◽  
Yuancheng Ji ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Targeted Drug Delivery ◽  
Anticancer Effect ◽  
Delivery Vehicle ◽  
Drug Delivery Vehicle ◽  
Highly Efficient ◽  
Targeted Drug

A new highly efficient targeting drug delivery vehicle based on diselenium-containing ultrathin polymer nanocapsules was designed and prepared.

Preparation and characterization of an elastin nanogel with enhanced biocompatibility and improved entrapment efficiency in prostate cancer cells

2021 ◽  
Vol 11 (1) ◽  
pp. 16-27
Author(s):  
Vinoth-Kumar Lakshmanan ◽  
Byoungkwon Kim ◽  
Shreesh Ojha ◽  
Ahmed M. Al-Abd ◽  
Myung Geun Shin ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Drug Delivery ◽  
Targeted Drug Delivery ◽  
Room Temperature ◽  
Vascular Tissue ◽  
Prostate Cancer Cell ◽  
Drug Carrier ◽  
Entrapment Efficiency ◽  
Prostate Cancer Cells

Nanogels represent an emerging class of drug delivery systems with enhanced renal clearance and serum half-life. However, synthetic polymeric nanogels are immunogenic and less biodegradable than other systems. Protein nanogels, being non-immunogenic; biodegradable; biocompatible; and mechanically, spatially, and temporally tunable, are gaining widespread attention. Elastin, a natural structural component of connective tissue, has enhanced vascular mobility and is highly biodegradable, biocompatible, temperature and pH sensitive, inert in the bloodstream, able to self-assemble, and able to permeate the blood-brain-barrier. In this study, the development of an Elastin Nanogel (ENG) and its functional capacity as a next generation injectable nano-drug carrier was studied. ENG was prepared via an inverse mini-emulsion technique and was characterized and found to be stable at room temperature and cytocompatible with five different prostate cancer cell lines of varied etiologies. Rhodamine-loaded ENG showed enhanced cellular uptake. Blood smear, hemolysis, CBC, PT/APTT, and C3a complement activation assays showed that ENG is vascular tissue compatible and hence meets the objectives of injectable nanogels. The formulated ENG can be efficiently used as an injectable nano-drug carrier for cancer therapy. Moreover, ENG has the potential to encapsulate hydrophobic drugs for targeted drug delivery.

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