Development of pH sensitive polyurethane–alginate nanoparticles for safe and efficient oral insulin delivery in animal models

RSC Advances ◽  
2016 ◽  
Vol 6 (48) ◽  
pp. 41835-41846 ◽  
Author(s):  
Aditi Bhattacharyya ◽  
Debarati Mukherjee ◽  
Roshnara Mishra ◽  
P. P. Kundu
Keyword(s):  
Animal Models ◽  
Sodium Alginate ◽  
Polyethylene Terephthalate ◽  
Insulin Delivery ◽  
Ph Sensitive ◽  
Oral Insulin

Blends of sodium alginate (ALG) and polyurethane (PU) synthesized from depolymerised polyethylene terephthalate (PET) to formulate insulin loaded PU–ALG nanoparticles for the purpose of controlled oral insulin delivery.

pH-sensitive chitosan/alginate core-shell nanoparticles for efficient and safe oral insulin delivery

2015 ◽  
Vol 72 ◽  
pp. 640-648 ◽  
Author(s):  
Piyasi Mukhopadhyay ◽  
Souma Chakraborty ◽  
Sourav Bhattacharya ◽  
Roshnara Mishra ◽  
P.P. Kundu
Keyword(s):  
Insulin Delivery ◽  
Ph Sensitive ◽  
Core Shell ◽  
Oral Insulin ◽  
Shell Nanoparticles ◽  
Core Shell Nanoparticles

An efficient pH sensitive oral insulin delivery system enhanced by deoxycholic acid

2011 ◽  
Vol 152 ◽  
pp. e184-e186 ◽  
Author(s):  
Li Zhao ◽  
Jianxun Ding ◽  
Pan He ◽  
Chunsheng Xiao ◽  
Zhaohui Tang ◽  
...  
Keyword(s):  
Delivery System ◽  
Deoxycholic Acid ◽  
Insulin Delivery ◽  
Ph Sensitive ◽  
Oral Insulin ◽  
Insulin Delivery System

pH Sensitive Thiolated Cationic Hydrogel for Oral Insulin Delivery

2014 ◽  
Vol 10 (4) ◽  
pp. 642-650 ◽  
Author(s):  
T. A. Sonia ◽  
Chandra P. Sharma
Keyword(s):  
Insulin Delivery ◽  
Ph Sensitive ◽  
Oral Insulin

pH-sensitive chitosan-deoxycholic acid/alginate nanoparticles for oral insulin delivery

2021 ◽  
pp. 1-33
Author(s):  
Ya-Wen Zhang ◽  
Ling-Lan Tu ◽  
Zhan Tang ◽  
Qiao Wang ◽  
Gao-Li Zheng ◽  
...  
Keyword(s):  
Deoxycholic Acid ◽  
Insulin Delivery ◽  
Ph Sensitive ◽  
Oral Insulin

Novel Biodegradable and pH-Sensitive Poly(ester amide) Microspheres for Oral Insulin Delivery

2012 ◽  
Vol 12 (4) ◽  
pp. 547-556 ◽  
Author(s):  
Pan He ◽  
Zhaohui Tang ◽  
Lin Lin ◽  
Mingxiao Deng ◽  
Xuan Pang ◽  
...  
Keyword(s):  
Insulin Delivery ◽  
Ph Sensitive ◽  
Oral Insulin

Synthesis and characterization of pH sensitive poly(PEGDMA-MAA) copolymeric microparticles for oral insulin delivery

2007 ◽  
Vol 107 (2) ◽  
pp. 863-871 ◽  
Author(s):  
Amit Kumar ◽  
Sitanshu S. Lahiri ◽  
Supriya Punyani ◽  
Harpal Singh
Keyword(s):  
Insulin Delivery ◽  
Ph Sensitive ◽  
Synthesis And Characterization ◽  
Oral Insulin

pH‐Sensitive Polymeric Poly (ϵ‐caprolactone) Core‐ Chitosan/Alginate Shell Particle System for Oral Insulin Delivery

2021 ◽  
Vol 6 (4) ◽  
pp. 695-704
Author(s):  
Gokce D. Kalaycioglu ◽  
Arwa A. Elamin ◽  
Hurmet Kinali ◽  
Nihal Aydogan
Keyword(s):  
Particle System ◽  
Insulin Delivery ◽  
Ph Sensitive ◽  
Oral Insulin ◽  
Shell Particle

pH sensitive N-succinyl chitosan grafted polyacrylamide hydrogel for oral insulin delivery

2014 ◽  
Vol 112 ◽  
pp. 627-637 ◽  
Author(s):  
Piyasi Mukhopadhyay ◽  
Kishor Sarkar ◽  
Sourav Bhattacharya ◽  
Aditi Bhattacharyya ◽  
Roshnara Mishra ◽  
...  
Keyword(s):  
Insulin Delivery ◽  
Ph Sensitive ◽  
Oral Insulin ◽  
Polyacrylamide Hydrogel

Preparation and characterization of layer-by-layer hypoglycemic nanoparticles with pH-sensitivity for oral insulin delivery

2018 ◽  
Vol 6 (45) ◽  
pp. 7451-7461 ◽  
Author(s):  
Li Zhang ◽  
Han Qin ◽  
Jian Li ◽  
Jia-Ni Qiu ◽  
Jing-Min Huang ◽  
...  
Keyword(s):  
Delivery System ◽  
Oral Delivery ◽  
Insulin Delivery ◽  
Ph Sensitive ◽  
Ph Sensitivity ◽  
Oral Insulin ◽  
Layer By Layer ◽  
Sensitive Material ◽  
Oral Delivery System

We developed an insulin oral delivery system with the combination of pH-sensitive material and structure to avoid intestinal degradation.

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