Boronic acid functionalized magnetic nanoparticles synthesized by atom transfer radical polymerization and their application for selective enrichment of glycoproteins

RSC Advances ◽  
2016 ◽  
Vol 6 (52) ◽  
pp. 47055-47061 ◽  
Author(s):  
Jiewen Wang ◽  
Xiwen He ◽  
Langxing Chen ◽  
Yukui Zhang

A facile and efficient approach to synthesize boronate affinity ligand-functionalized magnetic nanoparticles for specific enrichment of glycoproteins via surface-initiated atom transfer radical polymerization (SI-ATRP) has been developed.

2016 ◽  
Vol 4 (36) ◽  
pp. 6125-6133 ◽  
Author(s):  
Xiangyang An ◽  
Xiwen He ◽  
Langxing Chen ◽  
Yukui Zhang

A facile and efficient method was developed to synthesize boronic acid polymer brushes immobilized on magnetic graphene oxide for the selective enrichment of glycoproteins from complex biological samples via surface initiated atom transfer radical polymerization (SI-ATRP).


2017 ◽  
Vol 41 (22) ◽  
pp. 13399-13407 ◽  
Author(s):  
Lei Gu ◽  
Yun Wang ◽  
Juan Han ◽  
Lei Wang ◽  
Xu Tang ◽  
...  

We developed an efficient and mild method for the preparation of boronic acid-functionalized magnetic nanoparticles (MNPs), and the selective separation of fructose from a sample solution was demonstrated for the first time.


2015 ◽  
Vol 7 (11) ◽  
pp. 4708-4716 ◽  
Author(s):  
Xuedong Mao ◽  
Hongyu Sun ◽  
Xiwen He ◽  
Langxing Chen ◽  
Yukui Zhang

A facile and efficient approach combining surface-initiated atom transfer radical polymerization (ATRP) to prepare Fe3O4@SMZ-MIP core–shell nanoparticles is presented. The MIPs exhibit high adsorption capacity and selectivity.


The Analyst ◽  
2017 ◽  
Vol 142 (23) ◽  
pp. 4494-4502 ◽  
Author(s):  
Daojin Li ◽  
Zijun Bie

Boronate affinity materials, as efficient sorbents for extraction, separation and enrichment of glycoproteins, have attracted more and more attention in recent years.


The Analyst ◽  
2019 ◽  
Vol 144 (2) ◽  
pp. 641-648 ◽  
Author(s):  
Xiaoting Xue ◽  
Rui Lu ◽  
Min Liu ◽  
Yi Li ◽  
Jiansheng Li ◽  
...  

Biomedical applications and biomarkers for early clinical diagnostics and the treatment of diseases demand efficient and selective enrichment platforms for glycoproteins.


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