Preparation and characterization of foamy poly(γ-benzyl-l-glutamate-co-l-phenylalanine)/bioglass composite scaffolds for bone tissue engineering

RSC Advances ◽  
2016 ◽  
Vol 6 (77) ◽  
pp. 73699-73708 ◽  
Author(s):  
Ning Cui ◽  
Junmin Qian ◽  
Jinlei Wang ◽  
Chuanlei Ji ◽  
Weijun Xu ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Amino Acid ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Ring Opening ◽  
Ring Opening Polymerization ◽  
Composite Scaffolds ◽  
Templating Method

Novel foamy scaffolds of poly(γ-benzyl-l-glutamate) and poly(γ-benzyl-l-glutamate-co-l-phenylalanine) were fabricated via a combination of a sintered NaCl templating method and ring-opening polymerization of α-amino acid N-carboxyanhydrides.

Preparation and characterization of nano-sized hydroxyapatite/alginate/chitosan composite scaffolds for bone tissue engineering

2015 ◽  
Vol 54 ◽  
pp. 20-25 ◽  
Author(s):  
Hye-Lee Kim ◽  
Gil-Yong Jung ◽  
Jun-Ho Yoon ◽  
Jung-Suk Han ◽  
Yoon-Jeong Park ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Composite Scaffolds ◽  
Chitosan Composite

scholarly journals Enzyme-Mediated Ring-Opening Polymerization of Pentadecalactone to Obtain Biodegradable Polymer for Fabrication of Scaffolds for Bone Tissue Engineering

2013 ◽  
Vol 2013 ◽  
pp. 1-10 ◽  
Author(s):  
V. A. Korzhikov ◽  
K. V. Gusevskaya ◽  
E. N. Litvinchuk ◽  
E. G. Vlakh ◽  
T. B. Tennikova
Keyword(s):  
Tissue Engineering ◽  
Molecular Weight ◽  
Phase Separation ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Biodegradable Polymer ◽  
Ring Opening ◽  
Monomer Concentration ◽  
Ring Opening Polymerization ◽  
Enzyme Ratio

The optimization of enzyme-mediated polymerization of pentadecalactone (PDL) was performed to obtain macromolecular products suitable for generation of 3D cell supports (scaffolds) for bone tissue engineering. Such parameters as temperature, monomer/enzyme ratio, and monomer concentration were studied. The maximum molecular weight of synthesized polymers was about 90,000. Methods allowing the introduction of reactive double bonds into polypentadecalactone (polyPDL) structure were developed. The macroporous matrices were obtained by modification of thermoinduced phase separation method.

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