Rapid magnetic solid-phase extraction combined with ultra-high performance liquid chromatography and quadrupole-time-of-flight mass spectrometry for analysis of thrombin binders from a crude extract and injection of Erigeron breviscapus

RSC Advances ◽  
2016 ◽  
Vol 6 (41) ◽  
pp. 34782-34790 ◽  
Author(s):  
Yi Tao ◽  
Yanhui Jiang ◽  
Weidong Li ◽  
Baochang Cai
Keyword(s):  
Mass Spectrometry ◽  
High Performance Liquid Chromatography ◽  
High Performance ◽  
Solid Phase ◽  
Magnetic Solid Phase Extraction ◽  
Phase Extraction ◽  
Flight Mass Spectrometry ◽  
Magnetic Solid ◽  
Erigeron Breviscapus ◽  
Coagulation Pathway

Thrombin, which acts as a serine protease that converts soluble fibrinogen into insoluble strands of fibrin, plays crucial roles in the blood coagulation pathway.

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