Systematical investigation of in vitro molecular interaction between fluorescent carbon dots and human serum albumin

RSC Advances ◽  
2016 ◽  
Vol 6 (50) ◽  
pp. 44531-44542 ◽  
Author(s):  
Shan Huang ◽  
Hangna Qiu ◽  
Jiangning Xie ◽  
Chusheng Huang ◽  
Wei Su ◽  
...  
Keyword(s):  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Molecular Interaction ◽  
Carbon Dots ◽  
Electrochemical Techniques ◽  
Fluorescent Carbon Dots ◽  
Fluorescent Carbon

In vitro molecular interaction between fluorescent CDs and HSA was systematically investigated by multispectroscopic and electrochemical techniques.

scholarly journals In-vitro molecular interaction of boron doped carbon dots with human serum albumin

2021 ◽  
Vol 1120 (1) ◽  
pp. 012012
Author(s):  
Vinayak Sahu ◽  
Fahmida Khan ◽  
Pradeep Kumar Dewangan ◽  
Komal Kashyap ◽  
Sonalika Agrawal ◽  
...  
Keyword(s):  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Molecular Interaction ◽  
Carbon Dots ◽  
Boron Doped ◽  
Doped Carbon Dots

Spectroscopic studies on in vitro molecular interaction of highly fluorescent carbon dots with different serum albumins

2018 ◽  
Vol 255 ◽  
pp. 279-287 ◽  
Author(s):  
Reshma ◽  
Sandeep Kumar Vaishnav ◽  
Indrapal Karbhal ◽  
Manmohan L. Satnami ◽  
Kallol K. Ghosh
Keyword(s):  
Molecular Interaction ◽  
Carbon Dots ◽  
Spectroscopic Studies ◽  
Serum Albumins ◽  
Fluorescent Carbon Dots ◽  
Fluorescent Carbon

Carbon dots derived from Fusobacterium nucleatum for intracellular determination of Fe3+ and bioimaging both in vitro and in vivo

2021 ◽  
Author(s):  
Lijuan Liu ◽  
Shengting Zhang ◽  
Xiaodan Zheng ◽  
Hongmei Li ◽  
Qi Chen ◽  
...  
Keyword(s):  
Carbon Dots ◽  
Fusobacterium Nucleatum ◽  
Living Cells ◽  
First Time ◽  
Fluorescent Carbon Dots ◽  
Fluorescent Carbon

Fusobacterium nucleatum has been employed for the first time to synthesize fluorescent carbon dots which could be applied for the determination of Fe3+ ions in living cells and bioimaging in vitro and in vivo with excellent biocompatibility.

Nof2206Probing the interaction of memantine, an important Alzheimer's drug, with human serum albumin: In silico and In vitro approach

2021 ◽  
pp. 116888
Author(s):  
Fahad A. Alhumaydhi ◽  
Mohammad Abdullah Aljasir ◽  
Abdullah S.M. Aljohani ◽  
Suliman A. Alsagaby ◽  
Ameen S.S. Alwashmi ◽  
...  
Keyword(s):  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
In Silico

Fluorescent Carbon Dots an Effective Nano-Thermometer in Vitro Applications

2021 ◽  
Author(s):  
Waheed Ullah Khan ◽  
Liying Qin ◽  
Abid Alam ◽  
Ping Zhou ◽  
Yong Peng ◽  
...  
Keyword(s):  
Carbon Dots ◽  
Fluorescent Carbon Dots ◽  
Fluorescent Carbon

scholarly journals Synthesis and In Vitro Assessment of pH-Sensitive Human Serum Albumin Conjugates of Pirarubicin

2020 ◽  
Vol 14 (1) ◽  
pp. 22
Author(s):  
Kenji Tsukigawa ◽  
Shuhei Imoto ◽  
Keishi Yamasaki ◽  
Koji Nishi ◽  
Toshihiko Tsutsumi ◽  
...  
Keyword(s):  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Coupling Reaction ◽  
Synthetic Polymer ◽  
Ph Sensitive ◽  
Acidic Ph ◽  
Polymer Conjugate ◽  
Acidic Conditions

In a previous study, we reported on the development of a synthetic polymer conjugate of pirarubicin (THP) that was formed via an acid-labile hydrazone bond between the polymer and the THP. However, the synthetic polymer itself was non-biodegradable, which could lead to unexpected adverse effects. Human serum albumin (HSA), which has a high biocompatibility and good biodegradability, is also a potent carrier for delivering antitumor drugs. The objective of this study was to develop pH-sensitive HSA conjugates of THP (HSA-THP), and investigate the release of THP and the cytotoxicity under acidic conditions in vitro for further clinical development. HSA-THP was synthesized by conjugating maleimide hydrazone derivatives of THP with poly-thiolated HSA using 2-iminothiolane, via a thiol-maleimide coupling reaction. We synthesized two types of HSA-THP that contained different amounts of THP (HSA-THP2 and HSA-THP4). Free THP was released from both of the HSA conjugates more rapidly at an acidic pH, and the rates of release for HSA-THP2 and HSA-THP4 were similar. Moreover, both HSA-THPs exhibited a higher cytotoxicity at acidic pH than at neutral pH, which is consistent with the effective liberation of free THP under acidic conditions. These findings suggest that these types of HSA-THPs are promising candidates for further development.

Fluorescent carbon dots from milk by microwave cooking

RSC Advances ◽  
2016 ◽  
Vol 6 (47) ◽  
pp. 41516-41521 ◽  
Author(s):  
Dan Wang ◽  
Lin Zhu ◽  
Christopher Mccleese ◽  
Clemens Burda ◽  
Jian-Feng Chen ◽  
...  
Keyword(s):  
Carbon Dots ◽  
Cell Imaging ◽  
Two Photon ◽  
Microwave Cooking ◽  
Fluorescent Carbon Dots ◽  
Fluorescent Carbon

Fluorescent carbon dots were synthesized from milk by microwave cooking and used for two-photon excitedin vitrocell imaging.

The in Vitro Anti-HIV Efficacy of Negatively Charged Human Serum Albumin Is Antagonized by Heparin

1997 ◽  
Vol 13 (8) ◽  
pp. 677-683 ◽  
Author(s):  
P.J. SWART ◽  
C.S. SUN ◽  
M.E. KUIPERS ◽  
C. ASUNCION ◽  
S. JOSEPHS ◽  
...  
Keyword(s):  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Anti Hiv
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