Deep eutectic solvent mediated synthesis of quinazolinones and dihydroquinazolinones: synthesis of natural products and drugs

RSC Advances ◽  
2016 ◽  
Vol 6 (33) ◽  
pp. 27378-27387 ◽  
Author(s):  
Suman Kr Ghosh ◽  
Rajagopal Nagarajan

A mild and greener protocol was developed to synthesize substituted quinazolinones and dihydroquinazolinones via deep eutectic solvent mediated cyclization with aliphatic, aromatic, and heteroaromatic aldehydes in good to excellent yields.

2016 ◽  
Vol 1443 ◽  
pp. 262-266 ◽  
Author(s):  
Man Wang ◽  
Jiaqin Wang ◽  
Yue Zhang ◽  
Qian Xia ◽  
Wentao Bi ◽  
...  

RSC Advances ◽  
2021 ◽  
Vol 11 (29) ◽  
pp. 17924-17935
Author(s):  
Lei Wang ◽  
Xianying Fang ◽  
Yang Hu ◽  
Yiwei Zhang ◽  
Zhipeng Qi ◽  
...  

In recent years, deep eutectic solvent (DES) has attracted comprehensive attention on the extraction of natural products, and is regarded as an alternative to traditional organic solvents for the environmental advantages.


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