Gold nanoparticles/Orange II functionalized graphene nanohybrid based electrochemical aptasensor for label-free determination of insulin

RSC Advances ◽  
2016 ◽  
Vol 6 (36) ◽  
pp. 30732-30738 ◽  
Author(s):  
Tingting Li ◽  
Zhiguang Liu ◽  
Li Wang ◽  
Yujing Guo
Keyword(s):  
Gold Nanoparticles ◽  
Electrode Surface ◽  
Insulin Binding ◽  
Orange Ii ◽  
Functionalized Graphene ◽  
Label Free ◽  
Electrochemical Aptasensor

Nanocomposites, gold nanoparticles on Orange II functionalized graphene (AuNPs/O-GNs), were developed to modify the electrode surface for anchoring an insulin binding aptamer.

Novel label-free electrochemical aptasensor for determination of Diazinon using gold nanoparticles-modified screen-printed gold electrode

2018 ◽  
Vol 120 ◽  
pp. 122-128 ◽  
Author(s):  
Shokoufeh Hassani ◽  
Milad Rezaei Akmal ◽  
Armin Salek-Maghsoudi ◽  
Soheila Rahmani ◽  
Mohammad Reza Ganjali ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Gold Electrode ◽  
Label Free ◽  
Electrochemical Aptasensor ◽  
Screen Printed

Electrochemical aptasensor based on Mo2C/Mo2N and gold nanoparticles for determination of chlorpyrifos

2021 ◽  
Vol 188 (5) ◽  
Author(s):  
Zhenfeng Lin ◽  
Xin Liu ◽  
Yangzi Li ◽  
Changxiang Li ◽  
Liu Yang ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Electrochemical Aptasensor

Encapsulation of hemin in Fe-based metal-organic frameworks and its application for the direct determination of aflatoxin M1

2021 ◽  
pp. 1-10
Author(s):  
F. Jahangiri-Dehaghani ◽  
H.R. Zare ◽  
Z. Shekari
Keyword(s):  
Electrochemical Impedance ◽  
Metal Organic Frameworks ◽  
Direct Determination ◽  
Differential Pulse ◽  
Aflatoxin M1 ◽  
Label Free ◽  
Electrochemical Aptasensor ◽  
Selective Determination ◽  
Metal Organic

A label-free electrochemical aptasensor was constructed for the sensitive and selective determination of AFM1. For preparation of the aptasensor, the AFM1 aptamer was immobilised on the surface of a glassy carbon electrode modified with hemin encapsulated in Fe-based metal-organic frameworks (hemin@Fe-MIL-101). The morphology and the structure of Fe-MIL-101 and hemin@Fe-MIL-101 were evaluated by scanning electron microscopy, Fourier-transform infrared spectroscopy, X-ray powder diffraction and Brunauer-Emmett-Teller-N2 sorption methods. Electrochemical impedance spectroscopy and cyclic voltammetry were performed to monitor the fabrication process of the electrochemical aptasensor. The electrochemical reduction current of hemin encapsulated in Fe-MIL-101 serves as a signal for the quantitative determination of AFM1. Differential pulse voltammetry was done to determine the AFM1 concentration in the linear range of 1.0×10-1-100.0 ng/ml. The detection limit of AFM1 was estimated to be 4.6×10-2 ng/ml. Finally, the fabricated aptasensor was applied to determine AFM1 in raw and boiled milk samples.

scholarly journals Label-Free and Sensitive Determination of Cadmium Ions Using a Ti-Modified Co3O4-Based Electrochemical Aptasensor

Biosensors ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. 195
Author(s):  
Yang Liu ◽  
Dongwei Zhang ◽  
Jina Ding ◽  
Kashif Hayat ◽  
Xijia Yang ◽  
...  
Keyword(s):  
Environmental Protection Agency ◽  
Concentration Limit ◽  
Co3o4 Nanoparticles ◽  
Label Free ◽  
Current Signal ◽  
Electrochemical Aptasensor ◽  
Screen Printed Carbon Electrode ◽  
Sensitive Determination

The current work demonstrates an electrochemical aptasensor for sensitive determination of Cd2+ based on the Ti-modified Co3O4 nanoparticles. In this unlabeled system, Ti-modified Co3O4 nanoparticles act as current signal amplifiers modified on the screen-printed carbon electrode (SPCE) surface, while the derivative aptamer of Cd2+ works as a target recognizer. In addition, the sensing is based on the increase in electrochemical probe thionine current signal due to the binding of aptamer to Cd2+ via specific recognition. In the current study, key parameters, including aptamer concentration, pH, and incubation time were optimized, respectively, to ensure sensing performance. Cyclic voltammetry was used not only to characterize each preparation and optimization step, but also to profile the bindings of aptamer to Cd2+. Under optimal conditions, Cd2+ can be determined in a linear range of 0.20 to 15 ng/mL, with a detection limit of 0.49 ng/mL, significantly below the maximum concentration limit set by the U.S. Environmental Protection Agency. Based on comparative analysis and the results of recovery test with real samples, this simple, label-free but highly selective method has considerable potential and thus can be used as an in-situ environmental monitoring platform for Cd2+ testing.

A Simple and Sensitive Voltammetric Method for the Determination of Orange II Based on a Functionalized Graphene-Modified Electrode

2016 ◽  
Vol 99 (5) ◽  
pp. 1287-1294 ◽  
Author(s):  
Yudong Gao ◽  
Zhengkun Xie ◽  
Yulong Zhang ◽  
Lina Zou ◽  
Baoxian Ye
Keyword(s):  
Phosphate Buffer Solution ◽  
Linear Sweep Voltammetry ◽  
Food Samples ◽  
Orange Ii ◽  
Voltammetric Sensor ◽  
Functionalized Graphene ◽  
Modified Glassy Carbon Electrode ◽  
Buffer Solution ◽  
Accumulation Ability

Abstract A simple and sensitive voltammetric sensor for Orange II was developed, based on a poly(sodium p-styrenesulfonate)-functionalized graphene-modified glassy carbon electrode. This voltammetric sensor showed strong accumulation ability and an excellent voltammetric response for Orange II. The electrochemical behavior of Orange II was systematically investigated in a pH 7.0 phosphate buffer solution. By linear sweep voltammetry, under optimum conditions, a good linear relationship was obtained between peak currents and Orange II concentrations in the wider range of 3 × 10−8 to 5 × 10−6 mol/L, with an LOD of 1 × 10−8 mol/L. In addition, the proposed Orange II sensor was successfully applied to real food samples with satisfactory recovery.

Determination of cysteamine using label-free gold nanoparticles

2012 ◽  
Vol 4 (10) ◽  
pp. 3193 ◽  
Author(s):  
Vladimir V. Apyari ◽  
Stanislava G. Dmitrienko ◽  
Viktoriya V. Arkhipova ◽  
Aydar G. Atnagulov ◽  
Yuri A. Zolotov
Keyword(s):  
Gold Nanoparticles ◽  
Label Free ◽  
Free Gold
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