scholarly journals A self-assembled peptide mimetic of a tubular host and a supramolecular polymer

2017 ◽  
Vol 8 (2) ◽  
pp. 396-403 ◽  
Author(s):  
Arpita Paikar ◽  
Apurba Pramanik ◽  
Tanmay Das ◽  
Debasish Haldar
Keyword(s):  
Supramolecular Polymer ◽  
Hydrophobic Core ◽  
Peptide Mimetic ◽  
Self Assembled

A tripeptide self-assembles in a helical manner to form a tubular host-like supramolecular nanotube. The tube with a hydrophobic core has been used to develop a supramolecular polymer.

Supramolecular polymer micelles self-assembled from α -cyclodextrin and PLLA–PCL based copolymers

2011 ◽  
Vol 152 ◽  
pp. e52-e54 ◽  
Author(s):  
Haiqing Dong ◽  
Yongyong Li ◽  
Huiyun Wen ◽  
Donglu Shi ◽  
Lijian Liu
Keyword(s):  
Supramolecular Polymer ◽  
Polymer Micelles ◽  
Self Assembled

Selective fluorescence sensing of H2PO4− by the anion induced formation of self-assembled supramolecular polymers

2020 ◽  
Vol 18 (20) ◽  
pp. 3858-3866 ◽  
Author(s):  
Paula Sabater ◽  
Fabiola Zapata ◽  
Adolfo Bastida ◽  
Antonio Caballero
Keyword(s):  
Halogen Bonding ◽  
Supramolecular Polymers ◽  
Supramolecular Polymer ◽  
Fluorescence Sensing ◽  
Tripodal Receptor ◽  
Self Assembled

H2PO4− anions induced the formation of a fluorescent supramolecular polymer by halogen bonding interactions in a bromoimidazolium based tripodal receptor.

Bis-Urea-Based Supramolecular Polymer: The First Self-Assembled Drag Reducer for Hydrocarbon Solvents

Langmuir ◽  
2010 ◽  
Vol 26 (3) ◽  
pp. 1482-1486 ◽  
Author(s):  
Edvaldo Sabadini ◽  
Kelly R. Francisco ◽  
Laurent Bouteiller
Keyword(s):  
Supramolecular Polymer ◽  
Hydrocarbon Solvents ◽  
Self Assembled

Supramolecular polymer chemistry: design, synthesis, characterization, and kinetics, thermodynamics, and fidelity of formation of self-assembled dendrimers

Tetrahedron ◽  
2002 ◽  
Vol 58 (4) ◽  
pp. 825-843 ◽  
Author(s):  
Fanwen Zeng ◽  
Steven C Zimmerman ◽  
Sergei V Kolotuchin ◽  
David E.C Reichert ◽  
Yuguo Ma
Keyword(s):  
Polymer Chemistry ◽  
Supramolecular Polymer ◽  
Design Synthesis ◽  
Self Assembled

Poly{2-vinyloxyethyl 3,4,5-tris[4-(n-dodecanyloxy)benzyloxy]benzoate}: a self-assembled supramolecular polymer similar to tobacco mosaic virus

1992 ◽  
Vol 2 (10) ◽  
pp. 1033 ◽  
Author(s):  
Virgil Percec ◽  
James Heck ◽  
Myong Lee ◽  
Goran Ungar ◽  
Alberto Alvarez-Castillo
Keyword(s):  
Tobacco Mosaic Virus ◽  
Mosaic Virus ◽  
Supramolecular Polymer ◽  
Self Assembled

Pillar[5]arene-based self-assembled linear supramolecular polymer driven by guest halogen–halogen interactions in solid and solution states

2020 ◽  
Vol 11 (19) ◽  
pp. 3305-3312 ◽  
Author(s):  
Talal F. Al-Azemi ◽  
Mickey Vinodh
Keyword(s):  
Supramolecular Polymer ◽  
Solid States ◽  
Self Assembled

A pillar[5]arene-based linear supramolecular polymer mediated by guest halogen–halogen interactions (C–Br⋯Br–C) was studied in both the solution and solid states.

scholarly journals Upper-rim functionalization and supramolecular polymerization of a feet-to-feet-connected biscavitand

2020 ◽  
Vol 56 (26) ◽  
pp. 3733-3736 ◽  
Author(s):  
Daisuke Shimoyama ◽  
Ryo Sekiya ◽  
Takeharu Haino
Keyword(s):  
Solid State ◽  
Good Yield ◽  
Supramolecular Polymer ◽  
Iodination Reaction ◽  
Self Assembled ◽  
Upper Rim ◽  
Supramolecular Polymerization

An octaiodobiscavitand was synthesized via an aromatic Finkelstein iodination reaction in good yield. An octa-functionalized biscavitand self-assembled to form a supramolecular polymer in the solid state.

Formation of lead chalcogenide quantum dot-based supramolecular polymer network via pillar[5]arene-based host–guest complexation

2021 ◽  
Author(s):  
Bingbing Shi ◽  
Yun-Fei Zhang ◽  
Zhenghua Zhang ◽  
Hong Yao ◽  
Wen-Juan Qu ◽  
...  
Keyword(s):  
Quantum Dot ◽  
Polymer Network ◽  
Supramolecular Polymer ◽  
Lead Chalcogenide ◽  
Recent Advances ◽  
Scientific Significance ◽  
Self Assembled

Due to their technological and scientific significance, materials which possess photoluminescent properties are widely applied in numerous fields. Despite recent advances in quantum dot (QD)-based self-assembled materials, QD-based fluorescent supramolecular...

Antitumor Cytokine DR5-B-Conjugated Polymeric Poly(N-vinylpyrrolidone) Nanoparticles with Enhanced Cytotoxicity in Human Colon Carcinoma 3D Cell Spheroids

2021 ◽  
Vol 7 (1) ◽  
pp. 8
Author(s):  
Anne Yagolovich ◽  
Andrey Kuskov ◽  
Pavel Kulikov ◽  
Leily Kurbanova ◽  
Anastasia Gileva ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
Colon Carcinoma ◽  
Delivery System ◽  
Polymeric Micelles ◽  
Polymeric Nanoparticles ◽  
Human Colon ◽  
Hydrophobic Core ◽  
Human Colon Carcinoma ◽  
Self Assembled

Self-assembled nanoparticles based on amphiphilic poly(N-vinylpyrrolidone) (Amph-PVP) were proposed earlier as a new drug delivery system. In the current work, we study the antitumor activity of Amph-PVP-based self-assembled polymeric micelles covalently conjugated with the antitumor receptor-specific TRAIL variant DR5-B (P-DR5-B). The Amph-PVP polymer was synthesized by the earlier developed one-step technique (Kulikov et al., Polym. Sci. Ser. D, 2017). To stabilize Amph-PVP associates, the hydrophobic core was loaded with the model substance prothionamide. For the covalent conjugation with DR5-B, the hydrophilic ends of polymeric chains were modified with maleimide, and a DR5-B N-terminal amino acid residue valine was mutated to cysteine (DR5-B/V114C). DR5-B/V114C was conjugated to the surface of polymeric micelles by the selective covalent interaction of N-terminal cysteine residue with maleimide on Amph-PVP. The cytotoxicity of DR5-B-conjugated Amph-PVP polymeric nanoparticles was investigated in 3D multicellular tumor spheroids (MCTS) of human colon carcinoma HCT116 and HT29 cells, generated by the RGD-induced self-assembly technique (Akasov et al., Int. J. Pharm., 2016). In DR5-B-sensitive HCT116 MCTS, the P-DR5-B activity slightly increased compared to that of DR5-B. However, in DR5-B-resistant HT29 MCTS, P-DR5-B significantly surpassed DR5-B in the antitumor activity. Thus, the conjugation of DR5-B with the Amph-PVP nanoparticles enhanced its tumor-cell killing capacity. In the current study, we obtain a new nano-scaled delivery system based on Amph-PVP self-aggregates coated with covalently conjugated antitumor DR5-specific cytokine DR5-B. P-DR5-B overcomes DR5-B-resistance of the human colon carcinoma MCTS in vitro. This makes Amph-PVP polymeric nanoparticles a prospective and versatile nano-scaled delivery system for the targeted proteins.

Sign in / Sign up

Export Citation Format

Share Document