MercuryII-mediated base pairs in DNA: unexpected behavior in metal ion binding and duplex stability induced by 2′-deoxyuridine 5-substituents

2017 ◽  
Vol 15 (4) ◽  
pp. 870-883 ◽  
Author(s):  
Xiurong Guo ◽  
Sachin A. Ingale ◽  
Haozhe Yang ◽  
Yang He ◽  
Frank Seela
Keyword(s):  
Base Pair ◽  
Metal Ion ◽  
Pair Formation ◽  
Ion Binding ◽  
Side Chains ◽  
Mercury Ions ◽  
Metal Ion Binding ◽  
Base Pairs ◽  
Triple Bonds ◽  
Duplex Stability

DNA accepts small substituents at the 5-position of 2′-deoxyuridine residues within mercury ion mediated dU–HgII–dU base pairs, while triple bonds interact with mercury ions and those with space demanding aromatic side chains block metal ion mediated base pair formation.

An Artificial Base Pair, Mediated by Hydrogen Bonding and Metal-Ion Binding

2007 ◽  
Vol 46 (29) ◽  
pp. 5602-5604 ◽  
Author(s):  
Fabian-Alexander Polonius ◽  
Jens Müller
Keyword(s):  
Hydrogen Bonding ◽  
Base Pair ◽  
Metal Ion ◽  
Ion Binding ◽  
Metal Ion Binding

Preparation and metal ion-binding properties of gramicidin S derivatives carrying picolinoyl groups on the ornithine side chains

1998 ◽  
pp. 3999-4004 ◽  
Author(s):  
Keiichi Yamada ◽  
Hirotaka Ozaki ◽  
Naoki Kanda ◽  
Hatsuo Yamamura ◽  
Shuki Araki ◽  
...  
Keyword(s):  
Metal Ion ◽  
Ion Binding ◽  
Side Chains ◽  
Metal Ion Binding ◽  
Binding Properties ◽  
Gramicidin S

Metal ion-binding properties of DNA duplexes containing thiopyrimidine base pairs

2012 ◽  
Vol 48 (36) ◽  
pp. 4347 ◽  
Author(s):  
Itaru Okamoto ◽  
Takashi Ono ◽  
Rimi Sameshima ◽  
Akira Ono
Keyword(s):  
Metal Ion ◽  
Ion Binding ◽  
Dna Duplexes ◽  
Metal Ion Binding ◽  
Base Pairs ◽  
Binding Properties

ChemInform Abstract: Preparation and Metal Ion-Binding Properties of Gramicidin S Derivatives Carrying Picolinoyl Groups on the Ornithine Side Chains.

ChemInform ◽  
2010 ◽  
Vol 30 (16) ◽  
pp. no-no
Author(s):  
Keiichi Yamada ◽  
Hirotaka Ozaki ◽  
Naoki Kanda ◽  
Hatsuo Yamamura ◽  
Shuki Araki ◽  
...  
Keyword(s):  
Metal Ion ◽  
Ion Binding ◽  
Side Chains ◽  
Metal Ion Binding ◽  
Binding Properties ◽  
Gramicidin S

Metal ion binding of modified pyrimidine-base pairs in DNA duplexes

2009 ◽  
Vol 53 (1) ◽  
pp. 17-18
Author(s):  
A. Ono ◽  
K. Iwamoto ◽  
K. Sugiyama ◽  
I. Okamoto
Keyword(s):  
Metal Ion ◽  
Ion Binding ◽  
Dna Duplexes ◽  
Metal Ion Binding ◽  
Base Pairs ◽  
Pyrimidine Base

Photophysical Characterisation, Metal Ion Binding and Enantiomeric Recognition of Chiral Ligands Containing Phenazine Fluorophore

2004 ◽  
Vol 69 (4) ◽  
pp. 885-896 ◽  
Author(s):  
Luisa Stella Dolci ◽  
Péter Huszthy ◽  
Erika Samu ◽  
Marco Montalti ◽  
Luca Prodi ◽  
...  
Keyword(s):  
Metal Ion ◽  
Photophysical Properties ◽  
Ion Binding ◽  
Metal Ion Binding ◽  
Ammonium Ions ◽  
Enantiomerically Pure ◽  
Binding Process ◽  
High Affinity ◽  
Enantiomeric Recognition ◽  
Chiral Species

Enantiomerically pure dimethyl- and diisobutyl-substituted phenazino-18-crown-6 ligands bind metal and ammonium ions and also primary aralkylammonium perchlorates in acetonitrile with high affinity, causing pronounced changes in their luminescence properties. In addition, they show enantioselectivity towards chiral primary aralkylammonium perchlorates. The possibility to monitor the binding process by photoluminescence spectroscopy can gain ground for the design of very efficient enantioselective chemosensors for chiral species. The observed changes in the photophysical properties are also an important tool for understanding the interactions present in the adduct.

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