New one-pot synthesis of N-fused isoquinoline derivatives by palladium-catalyzed C–H arylation: potent inhibitors of nucleotide pyrophosphatase-1 and -3

2016 ◽  
Vol 14 (48) ◽  
pp. 11402-11414 ◽  
Author(s):  
Elina Ausekle ◽  
Syeda Abida Ejaz ◽  
Shafi Ullah Khan ◽  
Peter Ehlers ◽  
Alexander Villinger ◽  
...  
Keyword(s):  
Biological Evaluation ◽  
Efficient Synthesis ◽  
One Pot ◽  
One Pot Synthesis ◽  
Nucleotide Pyrophosphatase ◽  
Palladium Catalyzed ◽  
Synthesis Procedure ◽  
Isoquinoline Derivatives

An efficient synthesis procedure for N-fused isoquinolines from gem-difluoroalkenes is described, and biological evaluation of the sythesized products as inhibitors of h-NPP-1 and -3 is reported.

Palladium-Catalyzed One-Pot Synthesis of C2-Quaternary Indolin-3-ones via 1H -indole-3-sulfonates Generated in Situ from 2-Alkynyl Arylazides and Sulfonic Acids

2017 ◽  
Vol 359 (23) ◽  
pp. 4147-4152 ◽  
Author(s):  
Xiaoxiang Zhang ◽  
Ping Li ◽  
Chang Lyu ◽  
Wanxiong Yong ◽  
Jing Li ◽  
...  
Keyword(s):  
Sulfonic Acids ◽  
One Pot ◽  
One Pot Synthesis ◽  
Palladium Catalyzed

ChemInform Abstract: One-Pot Synthesis of Arylketones from Aromatic Acids via Palladium-Catalyzed Suzuki Coupling.

ChemInform ◽  
2016 ◽  
Vol 47 (32) ◽  
Author(s):  
Hongxiang Wu ◽  
Baiping Xu ◽  
Yue Li ◽  
Fengying Hong ◽  
Dezhao Zhu ◽  
...  
Keyword(s):  
Suzuki Coupling ◽  
Aromatic Acids ◽  
One Pot ◽  
One Pot Synthesis ◽  
Palladium Catalyzed
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