Total synthesis, structural elucidation and anti-inflammatory activity evaluation of 2-deoxy-3,6-anhydro hexofuranoside derivatives isolated from Sauropus rostratus

2016 ◽  
Vol 14 (46) ◽  
pp. 10906-10913 ◽  
Author(s):  
Chenxi Zhang ◽  
Chengcheng Wang ◽  
Zihao Wang ◽  
Genzoh Tanabe ◽  
Osamu Muraoka ◽  
...  

The first total synthesis of four 2-deoxy-3,6-anhydro hexofuranoside derivatives isolated from Genus Sauropus rostratus was accomplished.

2008 ◽  
Vol 43 (7) ◽  
pp. 1432-1437 ◽  
Author(s):  
Federico Martínez-Ramos ◽  
Hector Salgado-Zamora ◽  
Maria Elena Campos-Aldrete ◽  
Estela Melendez-Camargo ◽  
Yazmín Márquez-Flores ◽  
...  

Molecules ◽  
2019 ◽  
Vol 24 (9) ◽  
pp. 1701
Author(s):  
Jinjie Li ◽  
Xiuting Li ◽  
Xin Wang ◽  
Xiangjian Zhong ◽  
Linlin Ji ◽  
...  

Four new sesquiterpenoids (1–4) and six known sesquiterpenoids (5–10), were isolated from the EtOAc phase of the ethanolic extract of Ainsliaea yunnanensis. Their structures were established by spectroscopic methods, including 1-D, 2-D NMR and HPLC-MS. All compounds were tested for their anti-inflammatory effect by the inhibition of the activity of NLRP3 inflammasome by blocking the self-slicing of pro-caspase-1, which is induced by nigericin, then the secretion of mature IL-1β, mediated by caspase-1, was suppressed. Unfortunately none of the compounds showed an anti-inflammatory effect.


2016 ◽  
Vol 31 (6) ◽  
pp. 1520-1526 ◽  
Author(s):  
Pramod K. Sharma ◽  
Sakshi Balwani ◽  
Divya Mathur ◽  
Shashwat Malhotra ◽  
Brajendra K. Singh ◽  
...  

2012 ◽  
Vol 53 (46) ◽  
pp. 6202-6204 ◽  
Author(s):  
Yu-Ren Liao ◽  
Ping-Chung Kuo ◽  
Shiow-Chyn Huang ◽  
Jun-Weil Liang ◽  
Tian-Shung Wu

Planta Medica ◽  
2010 ◽  
Vol 76 (16) ◽  
pp. 1892-1896 ◽  
Author(s):  
Jin Qi ◽  
Na Li ◽  
Jia-Hong Zhou ◽  
Bo-Yang Yu ◽  
Samuel Qiu

2008 ◽  
Vol 341 (5) ◽  
pp. 288-293 ◽  
Author(s):  
Xian-Yu Sun ◽  
Cheng-Xi Wei ◽  
Kyu-Yun Chai ◽  
Hu-Ri Piao ◽  
Zhe-Shan Quan

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