Tin powder-promoted one-pot synthesis of 3-spiro-fused or 3,3′-disubstituted 2-oxindoles

2016 ◽  
Vol 14 (40) ◽  
pp. 9533-9542 ◽  
Author(s):  
Juanjuan Wang ◽  
Danfeng Huang ◽  
Ke-Hu Wang ◽  
Xiansha Peng ◽  
Yingpeng Su ◽  
...  
Keyword(s):  
Lewis Acid ◽  
Efficient Method ◽  
Aromatic Amines ◽  
Catalytic Amount ◽  
One Pot ◽  
One Pot Synthesis ◽  
Acrylic Ester

A convenient and efficient method for the constructions of 3-spirooxindole derivatives or 3,3′-disubstituted oxindoles has been developed from one-pot reactions of isatins, hydrazides or aromatic amines, 2-(bromomethyl)acrylic ester in the presence of a catalytic amount of Brønsted or Lewis acid promoted by tin powder instead of toxic stannanes.

Novel One-pot Synthesis of Pyranocarbazole Derivatives via an Isocyanide-based Three-component Reaction

2020 ◽  
Vol 17 ◽  
Author(s):  
Visarapu Malathi ◽  
Pedavenkatagari Narayana Reddy ◽  
Pannala Padmaja
Keyword(s):  
Efficient Method ◽  
Atom Economy ◽  
Reaction Conditions ◽  
One Pot ◽  
Catalyst Free ◽  
One Pot Synthesis ◽  
Three Component Reaction ◽  
High Yields

Abstract:: An efficient method has been developed for the synthesis of new pyrano[3,2-c] and pyrano[3,2-a]carbazole de-rivatives via a three component reaction of 4-hydroxycarbazole or 2-hydroxycarbazole, isocyanides, and dialkylacetylenedi-carboxylates. Noteworthy features of this protocol include mild reaction conditions, catalyst-free, high atom-economy and high yields.

A heavy metal- and oxidant-free, one-pot synthesis of pyridines and fused pyridines based on a Lewis acid-catalyzed multicomponent reaction

2014 ◽  
Vol 50 (82) ◽  
pp. 12270-12272 ◽  
Author(s):  
V. P. Alex Raja ◽  
Giammarco Tenti ◽  
Subbu Perumal ◽  
J. Carlos Menéndez
Keyword(s):  
Heavy Metal ◽  
Lewis Acid ◽  
Multicomponent Reaction ◽  
One Pot ◽  
One Pot Synthesis ◽  
Acid Catalyzed

Pyridines and fused pyridines are accessible by a combination of a Lewis acid-catalyzed multicomponent reaction and aromatization involving loss of a 2-furylmethyl chain.

ChemInform Abstract: One-Pot Synthesis of 3,4-Dihydropyridin-2-ones via Tandem Reaction of Blaise Reaction Intermediate and Acrylic Ester.

ChemInform ◽  
2016 ◽  
Vol 47 (18) ◽  
Author(s):  
Tuanjie Meng ◽  
Lantao Liu ◽  
Huiyi Jia ◽  
Lifeng Ren ◽  
Cuilan Feng ◽  
...  
Keyword(s):  
Tandem Reaction ◽  
One Pot ◽  
Reaction Intermediate ◽  
One Pot Synthesis ◽  
Acrylic Ester

Merging gold catalysis, organocatalytic oxidation, and Lewis acid catalysis for chemodivergent synthesis of functionalized oxazoles from N-propargylamides

2017 ◽  
Vol 53 (75) ◽  
pp. 10366-10369 ◽  
Author(s):  
Shaoyu Mai ◽  
Changqing Rao ◽  
Ming Chen ◽  
Jihu Su ◽  
Jiangfeng Du ◽  
...  
Keyword(s):  
Transition Metal ◽  
Lewis Acid ◽  
Lewis Acids ◽  
Acid Catalysis ◽  
Gold Catalysis ◽  
One Pot ◽  
Catalytic Systems ◽  
One Pot Synthesis ◽  
The One ◽  
Cationic Gold

Novel catalytic systems consisting of cationic gold complexes, N-hydroxyphthalimide (NHPI), and transition-metal-based Lewis acids have been developed for the one-pot synthesis of functionalized oxazoles.

Lewis acid promoted construction of chromen-4-one and isoflavone scaffolds via regio- and chemoselective domino Friedel–Crafts acylation/Allan–Robinson reaction

2014 ◽  
Vol 12 (45) ◽  
pp. 9216-9222 ◽  
Author(s):  
Tanmoy Chanda ◽  
Sushobhan Chowdhury ◽  
Suvajit Koley ◽  
Namrata Anand ◽  
Maya Shankar Singh
Keyword(s):  
Lewis Acid ◽  
One Pot ◽  
One Pot Synthesis

An efficient one-pot synthesis of chromen-4-ones and isoflavones is achieved directly from phenols via the regio- and chemoselective domino Friedel–Crafts acylation/Allan–Robinson reaction.

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