Synthesis and biological evaluation of N-naphthoyl-phenylglyoxamide-based small molecular antimicrobial peptide mimics as novel antimicrobial agents and biofilm inhibitors

2016 ◽  
Vol 14 (14) ◽  
pp. 3623-3637 ◽  
Author(s):  
Shashidhar Nizalapur ◽  
Kitty K. K. Ho ◽  
Önder Kimyon ◽  
Eugene Yee ◽  
Thomas Berry ◽  
...  

The synthesis of novel glyoxamide-based antimicrobial peptide mimics is described.

2017 ◽  
Vol 2 (12) ◽  
pp. 3452-3461 ◽  
Author(s):  
Tsz Tin Yu ◽  
Shashidhar Nizalapur ◽  
Kitty K. K. Ho ◽  
Eugene Yee ◽  
Thomas Berry ◽  
...  

INDIAN DRUGS ◽  
2017 ◽  
Vol 54 (05) ◽  
pp. 11-15
Author(s):  
R. R Somani ◽  
◽  
P. K Chaskar ◽  
P. M. Patil

One of the principles of green chemistry emphasises on minimisation of environmental and economic impacts by developing synthetic reactions at ambient temperature and pressure.The rise of resistant strains of microorganisms is an issue of regularly expanding seriousness. Therefore, the development of new antimicrobial agents will remain a challenge for chemists. we herein report room temperature synthesis of newer heterocyclic compounds belonging to 1,3,4-oxadiazole scaffold. Their structures were confirmed using various spectroscopic techniques. These compounds were evaluated for antifungal, antibacterial and antitubercular activities.


2020 ◽  
Vol 5 (15) ◽  
pp. 4722-4727 ◽  
Author(s):  
Prashant P. Thakare ◽  
Abhijit D. Shinde ◽  
Abhijit P. Chavan ◽  
Narendra V. Nyayanit ◽  
Vivek D. Bobade ◽  
...  

2012 ◽  
Vol 28 (6) ◽  
pp. 1316-1323 ◽  
Author(s):  
Laxman K. Adsul ◽  
Babasaheb P. Bandgar ◽  
Hemant V. Chavan ◽  
Shivkumar S. Jalde ◽  
Valmik D. Dhakane ◽  
...  

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