Selective recognition of c-MYC G-quadruplex DNA using prolinamide derivatives

2016 ◽  
Vol 14 (24) ◽  
pp. 5761-5767 ◽  
Author(s):  
Ajay Chauhan ◽  
Sushovan Paladhi ◽  
Manish Debnath ◽  
Jyotirmayee Dash
Keyword(s):  
Biological Evaluation ◽  
Selective Recognition ◽  
Design Synthesis ◽  
Quadruplex Dna ◽  
G Quadruplex

Herein we report the design, synthesis, biophysical and biological evaluation of triazole containing prolinamide derivatives as selectivec-MYCG-quadruplex binding ligands.

scholarly journals A site-specific self-assembled light-up rotor probe for selective recognition and stabilization of c-MYC G-quadruplex DNA

Nanoscale ◽  
2020 ◽  
Vol 12 (24) ◽  
pp. 12950-12957
Author(s):  
Marco Deiana ◽  
Karam Chand ◽  
Jan Jamroskovic ◽  
Rabindra Nath Das ◽  
Ikenna Obi ◽  
...  
Keyword(s):  
Selective Recognition ◽  
Site Specific ◽  
Quadruplex Dna ◽  
G Quadruplex ◽  
Sensitivity And Selectivity ◽  
Self Assembled ◽  
A Site

A self-assembled light-up rotor probe with outstanding sensitivity and selectivity for the c-MYC promoter G-quadruplex DNA is reported.

Targeting the KRAS oncogene: Synthesis, physicochemical and biological evaluation of novel G-Quadruplex DNA binders

2020 ◽  
Vol 149 ◽  
pp. 105337 ◽  
Author(s):  
Federica D'Aria ◽  
Vincenzo Maria D'Amore ◽  
Francesco Saverio Di Leva ◽  
Jussara Amato ◽  
Marco Caterino ◽  
...  
Keyword(s):  
Biological Evaluation ◽  
Quadruplex Dna ◽  
G Quadruplex ◽  
Dna Binders

scholarly journals Selective recognition and stabilization of new ligands targeting the potassium form of the human telomeric G-quadruplex DNA

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Yi-Hwa Lin ◽  
Show-Mei Chuang ◽  
Pei-Ching Wu ◽  
Chun-Liang Chen ◽  
Sivakamavalli Jeyachandran ◽  
...  
Keyword(s):  
Selective Recognition ◽  
Quadruplex Dna ◽  
G Quadruplex

Design, synthesis and biological evaluation of 4-anilinoquinazoline derivatives as new c-myc G-quadruplex ligands

2016 ◽  
Vol 122 ◽  
pp. 264-279 ◽  
Author(s):  
Yin Jiang ◽  
Ai-Chun Chen ◽  
Guo-Tao Kuang ◽  
Shi-Ke Wang ◽  
Tian-Miao Ou ◽  
...  
Keyword(s):  
Biological Evaluation ◽  
Design Synthesis ◽  
G Quadruplex ◽  
Synthesis And Biological Evaluation

scholarly journals A Minimalistic Coumarin Turn-On Probe for Selective Recognition of Parallel G-Quadruplex DNA Structures

2021 ◽  
Author(s):  
Marco Deiana ◽  
Ikenna Obi ◽  
Måns Andreasson ◽  
Shanmugam Tamilselvi ◽  
Karam Chand ◽  
...  
Keyword(s):  
Selective Recognition ◽  
Quadruplex Dna ◽  
Dna Structures ◽  
Turn On ◽  
G Quadruplex
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