Quantifying intra- and extracellular aggregation of iron oxide nanoparticles and its influence on specific absorption rate

Nanoscale ◽  
2016 ◽  
Vol 8 (35) ◽  
pp. 16053-16064 ◽  
Author(s):  
Seongho Jeon ◽  
Katie R. Hurley ◽  
John C. Bischof ◽  
Christy L. Haynes ◽  
Christopher J. Hogan
2019 ◽  
Author(s):  
Hattie Ring ◽  
Sheng Tong ◽  
Zhe Gao ◽  
Navid Manuchehrabadi ◽  
Kaiyi Jiang ◽  
...  

This work evaluates MRI relaxation and the specific absorption rate properties of iron oxide nanoparticles (IONPs) as a function of diameter (6-32 nm). We conclude that the ideal IONP diameter for image guided heating applications is dependent on the magnetic field strength of the MRI for the intended application. <br>


RSC Advances ◽  
2017 ◽  
Vol 7 (22) ◽  
pp. 13159-13170 ◽  
Author(s):  
Debora Bonvin ◽  
Alla Arakcheeva ◽  
Angel Millán ◽  
Rafael Piñol ◽  
Heinrich Hofmann ◽  
...  

Introducing a hydrothermal step after coprecipitation leads to iron oxide nanoparticles with higher vacancy ordering, saturation magnetization and specific absorption rate.


2018 ◽  
Vol 8 (8) ◽  
pp. 1241 ◽  
Author(s):  
Cindy Yadel ◽  
Aude Michel ◽  
Sandra Casale ◽  
Jerome Fresnais

Iron oxide nanoparticles are intended to be used in bio-applications for drug delivery associated with hyperthermia. However, their interactions with complex media often induces aggregation, and thus a detrimental decrease of their heating efficiency. We have investigated the role of iron oxide nanoparticles dispersion into dense aggregates composed with magnetic/non-magnetic nanoparticles and showed that, when iron oxide nanoparticles were well-distributed into the aggregates, the specific absorption rate reached 79% of the value measured for the well-dispersed case. This study should have a strong impact on the applications of magnetic nanoparticles into nanostructured materials for therapy or catalysis applications.


2019 ◽  
Author(s):  
Hattie Ring ◽  
Sheng Tong ◽  
Zhe Gao ◽  
Navid Manuchehrabadi ◽  
Kaiyi Jiang ◽  
...  

This work evaluates MRI relaxation and the specific absorption rate properties of iron oxide nanoparticles (IONPs) as a function of diameter (6-32 nm). We conclude that the ideal IONP diameter for image guided heating applications is dependent on the magnetic field strength of the MRI for the intended application. <br>


2018 ◽  
Vol 20 (18) ◽  
pp. 12879-12887 ◽  
Author(s):  
Jeotikanta Mohapatra ◽  
Fanhao Zeng ◽  
Kevin Elkins ◽  
Meiying Xing ◽  
Madhav Ghimire ◽  
...  

An efficient heat activating mediator with an enhanced specific absorption rate (SAR) value is attained via control of the iron oxide (Fe3O4) nanoparticle size from 3 to 32 nm.


2013 ◽  
Vol 2013 ◽  
pp. 1-13 ◽  
Author(s):  
P. Burnham ◽  
N. Dollahon ◽  
C. H. Li ◽  
A. J. Viescas ◽  
G. C. Papaefthymiou

Comparative studies are presented of iron oxide nanoparticles in the 7–15 nm average diameter range ball milled in hexane in the presence of oleic acid. Transmission electron microscopy identified spherical particles of decreasing size as milling time and/or surfactant concentration increased. Micromagnetic characterization via Mössbauer spectroscopy at room temperature yielded broadened magnetic spectroscopic signatures, while macromagnetic characterization via vibrating sample magnetometry of 7-8 nm diameter particles showed largely superparamagnetic behavior at room temperature and hysteretic at 2 K. Zero-field and field-cooled magnetization curves exhibited a broad maximum at ~215 K indicating the presence of strong interparticle magnetic interactions. The specific absorption rates of ferrofluids based on these nanoparticle preparations were measured in order to test their efficacies as hyperthermia agents.


2014 ◽  
Vol 2 (28) ◽  
pp. 4426 ◽  
Author(s):  
Pablo Guardia ◽  
Andreas Riedinger ◽  
Simone Nitti ◽  
Giammarino Pugliese ◽  
Sergio Marras ◽  
...  

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