scholarly journals Fluorescent boronate-based polymer nanoparticles with reactive oxygen species (ROS)-triggered cargo release for drug-delivery applications

Nanoscale ◽  
2016 ◽  
Vol 8 (13) ◽  
pp. 6958-6963 ◽  
Author(s):  
Eliézer Jäger ◽  
Anita Höcherl ◽  
Olga Janoušková ◽  
Alessandro Jäger ◽  
Martin Hrubý ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Drug Delivery ◽  
Reactive Oxygen ◽  
Polymer Nanoparticles ◽  
Oxygen Species ◽  
Drug Delivery Applications

scholarly journals Conducting polymer nanoparticles for targeted cancer therapy

RSC Advances ◽  
2015 ◽  
Vol 5 (47) ◽  
pp. 37943-37956 ◽  
Author(s):  
Mona Doshi ◽  
Marissa Krienke ◽  
Saeid Khederzadeh ◽  
Henry Sanchez ◽  
Alicja Copik ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Cancer Therapy ◽  
Conducting Polymer ◽  
Targeted Delivery ◽  
Reactive Oxygen ◽  
Polymer Nanoparticles ◽  
Oxygen Species ◽  
Targeted Cancer Therapy ◽  
Fluorescence Bioimaging

Functionalized conducting polymer nanoparticles allow for targeted delivery, tracking by fluorescence bioimaging, and therapeutics through formation of reactive oxygen species.

Specific Cancer Cytosolic Drug Delivery Triggered by Reactive Oxygen Species-Responsive Micelles

2016 ◽  
Vol 17 (9) ◽  
pp. 3040-3047 ◽  
Author(s):  
Lu-Yi Yu ◽  
Geng-Min Su ◽  
Chi-Kang Chen ◽  
Yi-Ting Chiang ◽  
Chun-Liang Lo
Keyword(s):  
Reactive Oxygen Species ◽  
Drug Delivery ◽  
Reactive Oxygen ◽  
Oxygen Species ◽  
Specific Cancer

scholarly journals Reactive oxygen species and enzyme dual-responsive biocompatible drug delivery system for targeted tumor therapy

2020 ◽  
Vol 324 ◽  
pp. 330-340 ◽  
Author(s):  
Ning Zhao ◽  
Bingbing Ding ◽  
Ying Zhang ◽  
Jessica L. Klockow ◽  
Ken Lau ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Tumor Therapy ◽  
Reactive Oxygen ◽  
Oxygen Species ◽  
Dual Responsive

scholarly journals Reactive Oxygen Species Responsive Polymers for Drug Delivery Systems

2021 ◽  
Vol 9 ◽  
Author(s):  
Fengxiang Gao ◽  
Zhengrong Xiong
Keyword(s):  
Reactive Oxygen Species ◽  
Drug Delivery ◽  
Targeted Delivery ◽  
Reactive Oxygen ◽  
Molecular Structures ◽  
Chemical Mechanism ◽  
Oxygen Species ◽  
Polymer Carriers ◽  
Responsive Polymers ◽  
Responsive Polymer

Reactive oxygen species (ROS) play an essential role in regulating various physiological functions of living organisms; however, as the concentration of ROS increases in the area of a lesion, this may undermine cellular homeostasis, leading to a series of diseases. Using cell-product species as triggers for targeted regulation of polymer structures and activity represents a promising approach for the treatment. ROS-responsive polymer carriers allow the targeted delivery of drugs, reduce toxicity and side effects on normal cells, and control the release of drugs, which are all advantages compared with traditional small-molecule chemotherapy agents. These formulations have attracted great interest due to their potential applications in biomedicine. In this review, recent progresses on ROS responsive polymer carriers are summarized, with a focus on the chemical mechanism of ROS-responsive polymers and the design of molecular structures for targeted drug delivery and controlled drug release. Meanwhile, we discuss the challenges and future prospects of its applications.

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